Literature DB >> 25721825

Myoepithelial carcinoma of the parotid: a rare tumour that may provide diagnostic difficulty.

Emily Skelton1, Amanda C Jewison1, Keith Ramesar2, David Howlett3.   

Abstract

This report presents the case of a 57-year-old man with a 6-week history of a slowly enlarging lump in the right parotid gland. Initial ultrasound investigation confirmed a 3 cm solid mass located within the superficial lobe of the right parotid gland. Sonographically, the mass demonstrated possible malignant features with internal heterogeneity of architecture and some loss of marginal clarity. Ultrasound-guided core biopsy (USCB) of the mass reported a mixed neoplasm with epithelial and myoepithelial appearances consistent with likely benign adenoma or myoepithelioma. A right superficial parotidectomy was subsequently performed. Histological and immunohistochemical analysis of the excised specimen showed a myoepithelial carcinoma. Postoperative CT and MR staging scans did not show evidence of metastases and no further treatment was given following discussion of the case at the regional speciality multidisciplinary meeting. This case illustrates the clinical and pathological features of this rare salivary gland tumour, but also discusses the diagnostic difficulties that may be encountered preoperatively. 2015 BMJ Publishing Group Ltd.

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Mesh:

Year:  2015        PMID: 25721825      PMCID: PMC4342686          DOI: 10.1136/bcr-2014-206163

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

Review 1.  Diagnosing a parotid lump: fine needle aspiration cytology or core biopsy?

Authors:  D C Howlett
Journal:  Br J Radiol       Date:  2006-04       Impact factor: 3.039

2.  The use of fine needle core biopsy under ultrasound guidance in the diagnosis of a parotid mass.

Authors:  John Breeze; Allan Andi; Michael D Williams; David C Howlett
Journal:  Br J Oral Maxillofac Surg       Date:  2008-06-09       Impact factor: 1.651

3.  Myoepithelial carcinoma of the parotid gland.

Authors:  Mirela Carapina; Mario Jurić; Pero Bubalo; Miro Leventić
Journal:  Coll Antropol       Date:  2010-03

4.  Myoepithelial carcinoma of the salivary glands: behavior and management.

Authors:  Guangyan Yu; Daquan Ma; Kaihua Sun; Tiejun Li; Ye Zhang
Journal:  Chin Med J (Engl)       Date:  2003-02       Impact factor: 2.628

5.  CD10 (Neutral Endopeptidase) Expression in Myoepithelial Cells of Salivary Neoplasms.

Authors:  Catarina de Oliveira Neves; Andresa Borges Soares; Ana Flávia Costa; Vera Cavalcanti de Araujo; Cristiane Furuse; Priscila Bianchi Juliano; Albina Altemani
Journal:  Appl Immunohistochem Mol Morphol       Date:  2010-03

6.  Myoepithelial carcinoma arising in a pleomorphic adenoma of the parotid gland: report of a case with cytopathologic findings.

Authors:  Anil V Parwani; Giovanni Lujan; Syed Z Ali
Journal:  Acta Cytol       Date:  2006 Jan-Feb       Impact factor: 2.319

7.  Myoepithelioma of minor salivary gland origin. Light and electron microscopical study.

Authors:  F W Stromeyer; R C Haggitt; J F Nelson; J M Hardman
Journal:  Arch Pathol       Date:  1975-05

8.  Fine-needle aspiration cytology of myoepithelial carcinoma of salivary gland: Diagnostic challenge to cytopathologist.

Authors:  Shelly Sehgal; Prashant Goyal; Sompal Singh; Awanindra Kumar
Journal:  J Cytol       Date:  2013-07       Impact factor: 1.000

  8 in total
  2 in total

1.  [Myoepithelial carcinoma of the parotid gland: a rare tumor with diagnostic challenges].

Authors:  Elias Tenner; Edda Menke-Lechner; Stefan Edlinger; Melitta Kitzwoegerer; Georg Sprinzl
Journal:  Wien Med Wochenschr       Date:  2021-01-29

2.  Prognostic analysis and nomogram establishment in patients with head and neck myoepithelial carcinoma.

Authors:  Keyuan Liu; Chen Lin; Zhujun Xu; Linkun Zhang
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-01-23       Impact factor: 2.503

  2 in total

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