Literature DB >> 33510802

The Effect of Momordica charantia in the Treatment of Diabetes Mellitus: A Review.

Zhuo Liu1, Jing Gong2, Wenya Huang2, Fuer Lu3, Hui Dong3.   

Abstract

In recent years, many studies of Momordica charantia (MC) in the treatment of diabetes mellitus (DM) and its complications have been reported. This article reviewed the effect and mechanism of MC against diabetes, including the results from in vitro and in vivo experiments and clinical trials. The common side effects of MC were also summarized. We hope that it might open up new ideas for further mechanism exploration and clinical application as well as provide a scientific theoretical basis for the development of drugs or foods derived from MC.
Copyright © 2021 Zhuo Liu et al.

Entities:  

Year:  2021        PMID： 33510802      PMCID： PMC7826218          DOI： 10.1155/2021/3796265

Source DB:  PubMed          Journal:  Evid Based Complement Alternat Med        ISSN： 1741-427X            Impact factor:   2.629


  120 in total

1.  Antiproliferative and hypoglycemic cucurbitane-type glycosides from the fruits of Momordica charantia.

Authors:  Ping-Chun Hsiao; Chia-Ching Liaw; Syh-Yuan Hwang; Hui-Ling Cheng; Li-Jie Zhang; Chien-Chang Shen; Feng-Lin Hsu; Yao-Haur Kuo
Journal:  J Agric Food Chem       Date:  2013-03-12       Impact factor: 5.279

2.  Antidiabetic activities of a cucurbitane‑type triterpenoid compound from Momordica charantia in alloxan‑induced diabetic mice.

Authors:  Bowen Jiang; Mingli Ji; Wei Liu; Lili Chen; Zhiyu Cai; Yuqing Zhao; Xiuli Bi
Journal:  Mol Med Rep       Date:  2016-10-05       Impact factor: 2.952

3.  Bitter melon fruit extract has a hypoglycemic effect and reduces hepatic lipid accumulation in ob/ob mice.

Authors:  Dinia R Dwijayanti; Takumi Shimada; Toshinari Ishii; Tetsuya Okuyama; Yukinobu Ikeya; Eri Mukai; Mikio Nishizawa
Journal:  Phytother Res       Date:  2019-12-17       Impact factor: 5.878

4.  Hypoglycemic effect of bitter melon compared with metformin in newly diagnosed type 2 diabetes patients.

Authors:  Anjana Fuangchan; Paveena Sonthisombat; Tippawadee Seubnukarn; Rapeepan Chanouan; Pontap Chotchaisuwat; Viruch Sirigulsatien; Kornkanok Ingkaninan; Pinyupa Plianbangchang; Stuart T Haines
Journal:  J Ethnopharmacol       Date:  2011-01-04       Impact factor: 4.360

5.  Modulation of pancreatic β-cells in neonatally streptozotocin-induced type 2 diabetic rats by the ethanolic extract of Momordica charantia fruit pulp.

Authors:  Rahman Md Hafizur; Nurul Kabir; Sidra Chishti
Journal:  Nat Prod Res       Date:  2011-02       Impact factor: 2.861

6.  Polysaccharide with antioxidant, α-amylase inhibitory and ACE inhibitory activities from Momordica charantia.

Authors:  Hwee-Feng Tan; Chee-Yuen Gan
Journal:  Int J Biol Macromol       Date:  2016-01-08       Impact factor: 6.953

7.  Antioxidative and Antimelanogenesis Effect of Momordica charantia Methanol Extract.

Authors:  Sang Hee Park; Young-Su Yi; Mi-Yeon Kim; Jae Youl Cho
Journal:  Evid Based Complement Alternat Med       Date:  2019-05-02       Impact factor: 2.629

Review 8.  The Role of Momordica charantia in Resisting Obesity.

Authors:  Meiqi Fan; Eun-Kyung Kim; Young-Jin Choi; Yujiao Tang; Sang-Ho Moon
Journal:  Int J Environ Res Public Health       Date:  2019-09-04       Impact factor: 3.390

9.  Role of GLP-1 in the Hypoglycemic Effects of Wild Bitter Gourd.

Authors:  Ting-Ni Huang; Kan-Ni Lu; Yi-Ping Pai; Ching-Jang Huang
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-26       Impact factor: 2.629

10.  Biotransformation of Momordica charantia fresh juice by Lactobacillus plantarum BET003 and its putative anti-diabetic potential.

Authors:  Farhaneen Afzal Mazlan; M Suffian M Annuar; Yusrizam Sharifuddin
Journal:  PeerJ       Date:  2015-10-29       Impact factor: 2.984
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  6 in total

Review 1.  Momordica charantia L.-Diabetes-Related Bioactivities, Quality Control, and Safety Considerations.

Authors:  Serhat S Çiçek
Journal:  Front Pharmacol       Date:  2022-05-17       Impact factor: 5.988

2.  Managing Type 2 Diabetes: Beliefs and Daily Practices in First Generation Asian Indians in the United States.

Authors:  Rupinder M Deol; Lisa M Thompson; Kevin M Chun; Catherine Chesla
Journal:  SAGE Open Nurs       Date:  2022-01-07

3.  Wound healing by topical application of Momordica charantia L. formulations on mice.

Authors:  William Antonio Sagástegui-Guarniz; Carmen R Silva-Correa; Víctor E Villarreal-La Torre; María V González-Blas; Walter O Sagástegui-Guarniz; Abhel A Calderón-Peña; Cinthya L Aspajo-Villalaz; José L Cruzado-Razco; Julio Hilario-Vargas
Journal:  Vet World       Date:  2021-10-22

Review 4.  A detailed review on the phytochemical profiles and anti-diabetic mechanisms of Momordica charantia.

Authors:  Sunday Faith Oyelere; Oluwatobi Hezekiah Ajayi; Titilayo Eunice Ayoade; George Bueno Santana Pereira; Bolaji Charles Dayo Owoyemi; Ajibola Olaoluwa Ilesanmi; Olalekan Amos Akinyemi
Journal:  Heliyon       Date:  2022-04-06

Review 5.  Bioactives of Momordica charantia as Potential Anti-Diabetic/Hypoglycemic Agents.

Authors:  Bilin Xu; Zhiliang Li; Ting Zeng; Jianfeng Zhan; Shuzhen Wang; Chi-Tang Ho; Shiming Li
Journal:  Molecules       Date:  2022-03-28       Impact factor: 4.411

Review 6.  Natural products for the treatment and management of diabetes mellitus in Zimbabwe-a review.

Authors:  Remigio Usai; Stephen Majoni; Freeborn Rwere
Journal:  Front Pharmacol       Date:  2022-08-24       Impact factor: 5.988
  6 in total

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