Literature DB >> 3350851

No relevant influence on overall survival time in patients with metastatic breast cancer undergoing combination chemotherapy.

E Petru1, D Schmähl.   

Abstract

The results of clinical studies dealing with first and second line chemotherapy of metastatic breast cancer published between 1975 and early 1986 which involved 9350 women were reviewed. Our special aim was to evaluate combination chemotherapy and its influence on overall survival in late stage breast cancer patients. No significant improvement in overall survival times was found in this selected group of patients who were treated with intense palliative chemotherapy.

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Year:  1988        PMID: 3350851     DOI: 10.1007/bf00417834

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.553


  7 in total

1.  On the relevance of "second-line" cytotoxic chemotherapy in patients with metastatic breast cancer resistant to standard combinations.

Authors:  E Petru; D Schmähl
Journal:  Wien Klin Wochenschr       Date:  1986-12-05       Impact factor: 1.704

Review 2.  [Importance of the composition of various combination regimens in the chemotherapy of metastatic breast cancer].

Authors:  E Petru; D Schmähl
Journal:  Dtsch Med Wochenschr       Date:  1987-02-13       Impact factor: 0.628

3.  Antimetastatic effects of razoxane in a rat osteosarcoma model.

Authors:  F Wingen; H Spring; D Schmähl
Journal:  Clin Exp Metastasis       Date:  1987 Jan-Mar       Impact factor: 5.150

4.  Does more intense palliative treatment improve overall survival in metastatic breast cancer patients?

Authors:  J K Patel; T Nemoto; M Vezeridis; N Petrelli; O Suh; T L Dao
Journal:  Cancer       Date:  1986-02-01       Impact factor: 6.860

5.  Estrogen-linked 2-chloroethylnitrosoureas: anticancer efficacy in MNU-induced rat mammary carcinoma, uterine activity in mice and receptor interactions.

Authors:  M R Berger; J Floride; D Schmähl; J Schreiber; G Eisenbrand
Journal:  Eur J Cancer Clin Oncol       Date:  1986-10

6.  Synthesis, toxicity, and therapeutic efficacy of 4-amino-N-(2'-aminophenyl)-benzamide: a new compound preferentially active in slowly growing tumors.

Authors:  M R Berger; H Bischoff; E Fritschi; T Henne; M Herrmann; B L Pool; G Satzinger; D Schmähl; U Weiershausen
Journal:  Cancer Treat Rep       Date:  1985-12

7.  Alkyl phosphocholines: toxicity and anticancer properties.

Authors:  C Muschiol; M R Berger; B Schuler; H R Scherf; F T Garzon; W J Zeller; C Unger; H J Eibl; D Schmähl
Journal:  Lipids       Date:  1987-11       Impact factor: 1.880

  7 in total
  2 in total

1.  [Janus-faced character of chemotherapy: a comment on the Abel theses].

Authors:  D Schmähl
Journal:  Klin Wochenschr       Date:  1991-01-04

Review 2.  Postmenopausal breast cancer. Drug therapy in the 1990s.

Authors:  C I Falkson; G Falkson; H C Falkson
Journal:  Drugs Aging       Date:  1993 Mar-Apr       Impact factor: 3.923

  2 in total

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