Xiao Chen1, Jing Su2, Guojun Wang2, Han Zhao2, Shizhong Zhang2, Tao Liu2, Xindi Su3, Ning Zhou4. 1. Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan City, Shandong Province, China. 2. Shandong Taian City Central Hospital, Taian City, Shandong Province, China. 3. Jinzhou Medical University, Jinzhou City, Liaoning Province, China. 4. Shandong Taian City Central Hospital Branch, Taian City, Shandong Province, China.
Abstract
DESIGN: A systematic document retrieval of studies published in the past 10 years reporting periprocedural stroke/mortality/MI after carotid endarterectomy (CEA) related to the time between CEA and qualifying neurological symptoms. The application database has "PubMed, EMbase and Cochrane databases." RevMan5.3 software provided by the Cochrane collaboration was used for meta-analysis. RESULTS: A systematic literature search was conducted in databases. A total of 10 articles were included in this study. They were divided into early CEA and delayed CEA with operation within 48 h, 1 w, or 2 w after onset of neurological symptoms. Incidence of the postoperative stroke in patients undergoing delayed CEA (≥48 h) was significantly higher than patients with delayed CEA (<48 h) (OR = 2.14, 95% CI: 1.43-3.21, P = 0.0002). The postoperative mortality of patients after delayed CEA (≥48 h) was significantly higher than patients after early CEA (<48 h) (OR = 1.35, 95% CI: 1.06-1.71, P = 0.02). The risk of postoperative mortality of patients treated with delayed CEA (≥7 d) was significantly higher than patients after the early CEA group (<7 d) (OR = 1.69, 95% CI: 1.21-2.32, P = 0.001). CONCLUSION: Early CEA is safe and effective for a part of patients with symptomatic carotid stenosis, but a comprehensive preoperative evaluation of patients with carotid stenosis must be performed.
DESIGN: A systematic document retrieval of studies published in the past 10 years reporting periprocedural stroke/mortality/MI after carotid endarterectomy (CEA) related to the time between CEA and qualifying neurological symptoms. The application database has "PubMed, EMbase and Cochrane databases." RevMan5.3 software provided by the Cochrane collaboration was used for meta-analysis. RESULTS: A systematic literature search was conducted in databases. A total of 10 articles were included in this study. They were divided into early CEA and delayed CEA with operation within 48 h, 1 w, or 2 w after onset of neurological symptoms. Incidence of the postoperative stroke in patients undergoing delayed CEA (≥48 h) was significantly higher than patients with delayed CEA (<48 h) (OR = 2.14, 95% CI: 1.43-3.21, P = 0.0002). The postoperative mortality of patients after delayed CEA (≥48 h) was significantly higher than patients after early CEA (<48 h) (OR = 1.35, 95% CI: 1.06-1.71, P = 0.02). The risk of postoperative mortality of patients treated with delayed CEA (≥7 d) was significantly higher than patients after the early CEA group (<7 d) (OR = 1.69, 95% CI: 1.21-2.32, P = 0.001). CONCLUSION: Early CEA is safe and effective for a part of patients with symptomatic carotid stenosis, but a comprehensive preoperative evaluation of patients with carotid stenosis must be performed.
Authors: Caron B Rockman; Thomas S Maldonado; Glenn R Jacobowitz; Neal S Cayne; Paul J Gagne; Thomas S Riles Journal: J Vasc Surg Date: 2006-07-14 Impact factor: 4.268
Authors: Suman Annambhotla; Michael S Park; Mark L Keldahl; Mark D Morasch; Heron E Rodriguez; William H Pearce; Melina R Kibbe; Mark K Eskandari Journal: J Vasc Surg Date: 2012-08-01 Impact factor: 4.268
Authors: Anselmo de Athayde Costa E Silva; Alex Tadeu Viana da Cruz Júnior; Nathalya Ingrid Cardoso do Nascimento; Skarleth Raissa Andrade Candeira; Aline do Socorro Soares Cardoso Almeida; Ketlin Jaquelline Santana de Castro; Ramon Costa de Lima; Tatiana Generoso Campos Pinho Barroso; Givago da Silva Souza; Bianca Callegari Journal: Biomed Res Int Date: 2020-01-24 Impact factor: 3.411