Literature DB >> 33505646

The Effectiveness of Fluorescent Light Energy as Adjunct Therapy in Canine Deep Pyoderma: A Randomized Clinical Trial.

Andrea Marchegiani1, Alessandro Fruganti1, Andrea Spaterna1, Matteo Cerquetella1, Adolfo M Tambella1, Susan Paterson2.   

Abstract

A single centre, single-blinded, prospective, randomized, controlled clinical study was conducted to evaluate the effectiveness of twice weekly fluorescent light energy therapy (Phovia™) as adjunct to systemic antibiotics in the management of deep pyoderma in dogs. Dogs with clinical lesions consistent with deep pyoderma, positive bacterial culture, and showing neutrophil engulfing bacteria at cytology were included in the study. Assessments were undertaken weekly for 8 weeks and every 2 weeks thereafter until 12 weeks after enrolment. At each visit, lesions were scored and cytology was conducted to determine a neutrophil engulfing bacteria score. All dogs (Groups A and B) were treated with systemic antibiotic twice daily, and Group B received additionally Phovia twice weekly. Median treatment duration was 11.7 weeks for Group A and 5.7 weeks for Group B. After 8 weeks of treatment, the percentage of dogs that achieved clinical resolution was 35.0% and 88.0% for Groups A and B, respectively. Lesion scores showed highly statistically significant difference in favour of Group B from week 3 to 8, and neutrophil engulfing bacteria scores showed statistical difference from week 2 onwards in favour of Group B. These results indicate that Phovia, when used as an adjunct to systemic antibiotics, can accelerate time to clinical resolution in cases of canine deep pyoderma.
Copyright © 2021 Andrea Marchegiani et al.

Entities:  

Year:  2021        PMID: 33505646      PMCID: PMC7811420          DOI: 10.1155/2021/6643416

Source DB:  PubMed          Journal:  Vet Med Int        ISSN: 2042-0048


  31 in total

1.  Compliance with short-term oral antibacterial drug treatment in dogs.

Authors:  K Grave; H Tanem
Journal:  J Small Anim Pract       Date:  1999-04       Impact factor: 1.522

2.  Evaluation of fluorescence biomodulation in the real-life management of chronic wounds: the EUREKA trial.

Authors:  Marco Romanelli; Alberto Piaggesi; Giovanni Scapagnini; Valentina Dini; Agata Janowska; Elisabetta Iacopi; Carlotta Scarpa; Stéphane Fauverghe; Franco Bassetto
Journal:  J Wound Care       Date:  2018-11-02       Impact factor: 2.072

Review 3.  The effectiveness of systemic antimicrobial treatment in canine superficial and deep pyoderma: a systematic review.

Authors:  Jennifer F Summers; David C Brodbelt; Peter J Forsythe; Anette Loeffler; Anke Hendricks
Journal:  Vet Dermatol       Date:  2012-06-27       Impact factor: 1.589

4.  Clinical efficacy of low-level laser therapy on localized canine atopic dermatitis severity score and localized pruritic visual analog score in pedal pruritus due to canine atopic dermatitis.

Authors:  Ashley N Stich; Wayne S Rosenkrantz; Craig E Griffin
Journal:  Vet Dermatol       Date:  2014-06-09       Impact factor: 1.589

5.  Therapy of difficult cases of canine pyoderma with marbofloxacin: a report of 39 dogs.

Authors:  D N Carlotti; E Guaguere; D Pin; P Jasmin; E Thomas; V Guiral
Journal:  J Small Anim Pract       Date:  1999-06       Impact factor: 1.522

6.  Pathogenesis of canine interdigital palmar and plantar comedones and follicular cysts, and their response to laser surgery.

Authors:  David D Duclos; Ann M Hargis; Patrick W Hanley
Journal:  Vet Dermatol       Date:  2008-06       Impact factor: 1.589

7.  Fluorescence biomodulation in the management of canine interdigital pyoderma cases: a prospective, single-blinded, randomized and controlled clinical study.

Authors:  Andrea Marchegiani; Andrea Spaterna; Matteo Cerquetella; Adolfo M Tambella; Alessandro Fruganti; Susan Paterson
Journal:  Vet Dermatol       Date:  2019-08-13       Impact factor: 1.589

8.  Suggested guidelines for using systemic antimicrobials in bacterial skin infections: part 2-- antimicrobial choice, treatment regimens and compliance.

Authors:  L Beco; E Guaguère; C Lorente Méndez; C Noli; T Nuttall; M Vroom
Journal:  Vet Rec       Date:  2013-02-09       Impact factor: 2.695

9.  Prescribing practices of primary-care veterinary practitioners in dogs diagnosed with bacterial pyoderma.

Authors:  Jennifer F Summers; Anke Hendricks; David C Brodbelt
Journal:  BMC Vet Res       Date:  2014-10-08       Impact factor: 2.741

10.  Management of otitis externa with an led-illuminated gel: a randomized controlled clinical trial in dogs.

Authors:  Adolfo Maria Tambella; Anna Rita Attili; Francesca Beribè; Margherita Galosi; Andrea Marchegiani; Matteo Cerquetella; Angela Palumbo Piccionello; Cecilia Vullo; Andrea Spaterna; Alessandro Fruganti
Journal:  BMC Vet Res       Date:  2020-03-20       Impact factor: 2.741

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  3 in total

1.  Effect of Low-Level Laser Therapy on Bacterial Counts of Contaminated Traumatic Wounds in Dogs.

Authors:  Samuel Rico-Holgado; Gustavo Ortiz-Díez; María C Martín-Espada; Cristina Fernández-Pérez; María R Baquero-Artigao; María Suárez-Redondo
Journal:  J Lasers Med Sci       Date:  2021-12-12

2.  Fluorescence Biomodulation for Canine Interdigital Furunculosis: Updates for Once-Weekly Schedule.

Authors:  Andrea Marchegiani; Alessandro Fruganti; Alessandra Gavazza; Andrea Spaterna; Matteo Cerquetella
Journal:  Front Vet Sci       Date:  2022-06-20

3.  Critically Appraised Topic on Low-Level Laser Therapy (LLLT) in Dogs: An Advisable Treatment for Skin Diseases?

Authors:  Roberta Perego; Martina Mazzeo; Eva Spada; Daniela Proverbio
Journal:  Vet Sci       Date:  2022-09-14
  3 in total

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