Literature DB >> 33505298

NeuroAid II (MLC901) in Haemorrhagic Stroke.

Chai-Hoon Nowel Tan1, David Choy2, Narayanaswamy Venketasubramanian2.   

Abstract

Stroke is a leading cause of death and disability. NeuroAid (MLC601), which originates from Traditional Chinese Medicine, comprises herbal and animal components, and has been shown to improve the functional status of patients after ischaemic stroke. The use of NeuroAid II (MLC901), which comprises only the herbal components of MLC601, in haemorrhagic stroke has not been previously reported. Our patient is a 63-year-old male with a significant stroke risk factor of hypertension. He developed visual field defect, aphasia, unilateral weakness, and hemisensory loss. CT scan showed a left thalamic haemorrhage. In addition to anti-hypertensive therapy and intensive rehabilitation, he was prescribed MLC901. Over a period of 6 months, he had significant improvements in his motor, sensory, and speech function. There were no adverse events, serial brain CT scans showed resolution of the haemorrhage. MLC901 may have a role in post-stroke recovery after intracranial haemorrhage.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Haemorrhagic stroke; MLC901; NeuroAid II; Stroke recovery

Year:  2020        PMID: 33505298      PMCID: PMC7802497          DOI: 10.1159/000508588

Source DB:  PubMed          Journal:  Case Rep Neurol        ISSN: 1662-680X


  13 in total

Review 1.  Efficacy and safety of MLC601 (NeuroAiD®), a traditional Chinese medicine, in poststroke recovery: a systematic review.

Authors:  Fahad Javaid Siddiqui; Narayanaswamy Venketasubramanian; Edwin Shih-Yen Chan; Christopher Chen
Journal:  Cerebrovasc Dis       Date:  2013-03-14       Impact factor: 2.762

2.  A randomized trial to assess the long-term safety of NeuroAiD among Caucasian patients with acute ischemic stroke.

Authors:  Reza Bavarsad Shahripour; Ahmad Hemati; Ana Hosseinzadeh Maleki
Journal:  Chin J Integr Med       Date:  2014-04-02       Impact factor: 1.978

3.  Safety profile of MLC601 (Neuroaid) in acute ischemic stroke patients: A Singaporean substudy of the Chinese medicine neuroaid efficacy on stroke recovery study.

Authors:  Sherry H Y Young; Yudong Zhao; Angeline Koh; Rajinder Singh; Bernard P L Chan; Hui Meng Chang; N Venketasubramanian; Christopher Chen
Journal:  Cerebrovasc Dis       Date:  2010-04-16       Impact factor: 2.762

Review 4.  NeuroAiD: properties for neuroprotection and neurorepair.

Authors:  C Heurteaux; C Widmann; H Moha ou Maati; H Quintard; C Gandin; M Borsotto; J Veyssiere; B Onteniente; M Lazdunski
Journal:  Cerebrovasc Dis       Date:  2013-03-14       Impact factor: 2.762

Review 5.  Prediction of motor recovery after stroke: advances in biomarkers.

Authors:  Cathy M Stinear
Journal:  Lancet Neurol       Date:  2017-09-12       Impact factor: 44.182

6.  Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

Authors:  J Claude Hemphill; Steven M Greenberg; Craig S Anderson; Kyra Becker; Bernard R Bendok; Mary Cushman; Gordon L Fung; Joshua N Goldstein; R Loch Macdonald; Pamela H Mitchell; Phillip A Scott; Magdy H Selim; Daniel Woo
Journal:  Stroke       Date:  2015-05-28       Impact factor: 7.914

7.  Activation of ATP-sensitive potassium channels as an element of the neuroprotective effects of the Traditional Chinese Medicine MLC901 against oxygen glucose deprivation.

Authors:  H Moha Ou Maati; M Borsotto; F Chatelain; C Widmann; M Lazdunski; C Heurteaux
Journal:  Neuropharmacology       Date:  2012-05-30       Impact factor: 5.250

8.  Effect of Combined Treatment with MLC601 (NeuroAiDTM) and Rehabilitation on Post-Stroke Recovery: The CHIMES and CHIMES-E Studies.

Authors:  Nijasri C Suwanwela; Christopher L H Chen; Chun Fan Lee; Sherry H Young; San San Tay; Thirugnanam Umapathi; Annabelle Y Lao; Herminigildo H Gan; Alejandro C Baroque Ii; Jose C Navarro; Hui Meng Chang; Joel M Advincula; Sombat Muengtaweepongsa; Bernard P L Chan; Carlos L Chua; Nirmala Wijekoon; H Asita de Silva; John Harold B Hiyadan; Ka Sing Lawrence Wong; Niphon Poungvarin; Gaik Bee Eow; Narayanaswamy Venketasubramanian
Journal:  Cerebrovasc Dis       Date:  2018-09-05       Impact factor: 2.762

9.  An Investigation of the Use of Traditional Chinese Medicine and Complementary and Alternative Medicine in Stroke Patients.

Authors:  Mei-Ling Yeh; Wei-Ling Chiu; Yu-Jen Wang; Chyi Lo
Journal:  Holist Nurs Pract       Date:  2017 Nov/Dec       Impact factor: 1.000

10.  Danqi Piantang Jiaonang (DJ), a traditional Chinese medicine, in poststroke recovery.

Authors:  Christopher Chen; N Venketasubramanian; Robert N Gan; Caroline Lambert; David Picard; Bernard P L Chan; Edwin Chan; Marie G Bousser; Shi Xuemin
Journal:  Stroke       Date:  2009-01-22       Impact factor: 7.914

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