BACKGROUND: Hepatic artery thrombosis is an important cause of graft loss and ischemic biliary complications. The risk factors have been related to technical aspects of arterial anastomosis and non-surgical ones. AIM: To evaluate the risk factors for the development of hepatic artery thrombosis. METHODS: The sample consisted of 1050 cases of liver transplant. A retrospective and cross-sectional study was carried out, and the variables studied in both donor and recipient. RESULTS: Univariate analysis indicated that the variables related to hepatic artery thrombosis are: MELD (p=0.04) and warm time ischemia (p=0.005). In the multivariate analysis MELD=14.5 and warm ischemia time =35 min were independent risk factors for hepatic artery thrombosis. In the prevalence ratio test for analysis of the anastomosis as a variable, it was observed that patients with continuous suture had an increase in thrombosis when compared to interrupted suture. CONCLUSIONS: Prolonged warm ischemia time, calculated MELD and recipient age were independent risk factors for hepatic artery thrombosis after liver transplantation in adults. Transplanted patients with continuous suture had an increase in thrombosis when compared to interrupted suture. Re-transplantation due to hepatic artery thrombosis was associated with higher recipient mortality.
BACKGROUND:Hepatic artery thrombosis is an important cause of graft loss and ischemic biliary complications. The risk factors have been related to technical aspects of arterial anastomosis and non-surgical ones. AIM: To evaluate the risk factors for the development of hepatic artery thrombosis. METHODS: The sample consisted of 1050 cases of liver transplant. A retrospective and cross-sectional study was carried out, and the variables studied in both donor and recipient. RESULTS: Univariate analysis indicated that the variables related to hepatic artery thrombosis are: MELD (p=0.04) and warm time ischemia (p=0.005). In the multivariate analysis MELD=14.5 and warm ischemia time =35 min were independent risk factors for hepatic artery thrombosis. In the prevalence ratio test for analysis of the anastomosis as a variable, it was observed that patients with continuous suture had an increase in thrombosis when compared to interrupted suture. CONCLUSIONS: Prolonged warm ischemia time, calculated MELD and recipient age were independent risk factors for hepatic artery thrombosis after liver transplantation in adults. Transplanted patients with continuous suture had an increase in thrombosis when compared to interrupted suture. Re-transplantation due to hepatic artery thrombosis was associated with higher recipient mortality.
Authors: F Piscaglia; M Vivarelli; G La Barba; A M Morselli-Labate; S Taddei; A Cucchetti; G Martinelli; A Pinna; A Cavallari; L Bolondi Journal: Dig Liver Dis Date: 2006-09-20 Impact factor: 4.088
Authors: C K Oh; S J Pelletier; R G Sawyer; A R Dacus; C S McCullough; T L Pruett; H A Sanfey Journal: Transplantation Date: 2001-03-27 Impact factor: 4.939
Authors: K Mori; I Nagata; S Yamagata; H Sasaki; F Nishizawa; Y Takada; F Moriyasu; K Tanaka; Y Yamaoka; K Kumada Journal: Transplantation Date: 1992-08 Impact factor: 4.939
Authors: Lucas Ernani; Rodrigo Bronze de Martino; Wellington Andraus; Eduardo de Souza Martins Fernandes; Felipe Pedreira Tavares de Mello; Ronaldo Andrade; Leandro Savattone Pimentel; Luciana Bertocco de Paiva Haddad; Fabricio Ferreira Coelho; Paulo Herman; Luiz Augusto Carneiro D'Albuquerque Journal: Arq Bras Cir Dig Date: 2022-01-05
Authors: Lucas Ernani; Eduardo de Souza Martins Fernandes; Rodrigo Bronze de Martino; Fabricio Ferreira Coelho; Felipe Pedreira Tavares de Mello; Ronaldo Andrade; Leandro Savattone Pimentel; Luciana Bertocco de Paiva Haddad; Paulo Herman; Wellington Andraus; Luiz Augusto Carneiro D'Albuquerque Journal: Arq Bras Cir Dig Date: 2022-01-31