| Literature DB >> 3349439 |
Abstract
Cytogenetic analysis of a human renal cell carcinoma revealed a near-haploid chromosome number of 34 with the loss of one chromosome #1, #2, #3, #6, #7, #9, #10, #12, #13, #17, #18, and #21. Binucleated cells were observed in histologic, cytologic, as well as in cytogenetic preparations. The paper briefly discusses the binucleation-polyploidization as a possible compensatory mechanism to maintain the genetic balance in near-haploid cells.Entities:
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Year: 1988 PMID: 3349439 DOI: 10.1016/0165-4608(88)90219-1
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN: 0165-4608