Literature DB >> 33490373

Postural orthostatic tachycardia syndrome in patients of orthostatic intolerance symptoms: an ambispective study.

Dinesh Chouksey1, Pankaj Rathi1, Ajoy Sodani1, Rahul Jain1, Hashash Singh Ishar1.   

Abstract

BACKGROUND: A Postural orthostatic tachycardia syndrome (POTS) is infrequently diagnosed in routine practice because of the variable range of symptoms that could be seen in cardiac rhythm disorders, vertigo, chronic fatigue syndrome and anxiety panic disorder. POTS is a chronic debilitating condition that affects day to day efficient working of an individual. We have planned a study to look for POTS in patients who are having orthostatic intolerance symptoms and underwent a head-up tilt table test (HUTT). AIM: To study the prevalence of POTS in patients of orthostatic intolerance (OI) symptoms and to analyze symptomatology, its association with neurocardiogenic syncope (NCS), and its outcome.
METHODS: We reviewed the medical records of 246 patients presented with symptoms of OI seen at our centre from January 2010 till March 2019. Out of them, 40 patients included, those qualifying the criteria for POTS on HUTT.
RESULTS: The mean age of the cohort was 25.90 ± 10.33 years with a range of 15 to 55 years, and males comprised 52.5% (21/40) of total patients. The most frequent presenting orthostatic symptoms of POTS patients are loss of consciousness (77.5%), lightheadedness (75%), and palpitation (67.5%). A total of 18 patients (45%) had coexisting neurocardiogenic syncope.
CONCLUSION: POTS is a prevalent condition and have a significant impact on the quality of life, and the majority of patients may not present with OI symptoms during HUTT. We have to keep this possibility in young patients of transient loss of consciousness because it may coexist with NCS.
© 2021 the Author(s), licensee AIMS Press.

Entities:  

Keywords:  HUTT; Head-up tilt table test; POTS; POTS with syncope; Postural orthostatic tachycardia syndrome; neurocardiogenic syncope

Year:  2020        PMID: 33490373      PMCID: PMC7815479          DOI: 10.3934/Neuroscience.2021004

Source DB:  PubMed          Journal:  AIMS Neurosci        ISSN: 2373-8006


  29 in total

Review 1.  The postural orthostatic tachycardia syndrome: definitions, diagnosis, and management.

Authors:  Yousuf Kanjwal; Dan Kosinski; Blair P Grubb
Journal:  Pacing Clin Electrophysiol       Date:  2003-08       Impact factor: 1.976

Review 2.  A review of postural orthostatic tachycardia syndrome.

Authors:  Sheila Carew; Margaret O Connor; John Cooke; Richard Conway; Christine Sheehy; Aine Costelloe; Declan Lyons
Journal:  Europace       Date:  2009-01       Impact factor: 5.214

Review 3.  Postural tachycardia syndrome (POTS).

Authors:  Satish R Raj
Journal:  Circulation       Date:  2013-06-11       Impact factor: 29.690

4.  2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope.

Authors:  Robert S Sheldon; Blair P Grubb; Brian Olshansky; Win-Kuang Shen; Hugh Calkins; Michele Brignole; Satish R Raj; Andrew D Krahn; Carlos A Morillo; Julian M Stewart; Richard Sutton; Paola Sandroni; Karen J Friday; Denise Tessariol Hachul; Mitchell I Cohen; Dennis H Lau; Kenneth A Mayuga; Jeffrey P Moak; Roopinder K Sandhu; Khalil Kanjwal
Journal:  Heart Rhythm       Date:  2015-05-14       Impact factor: 6.343

5.  Postural tachycardia syndrome: clinical features and follow-up study.

Authors:  P Sandroni; T L Opfer-Gehrking; B R McPhee; P A Low
Journal:  Mayo Clin Proc       Date:  1999-11       Impact factor: 7.616

Review 6.  Postural tachycardia syndrome (POTS).

Authors:  Phillip A Low; Paola Sandroni; Michael Joyner; Win-Kuang Shen
Journal:  J Cardiovasc Electrophysiol       Date:  2009-01-16

7.  Higher postural heart rate increments on head-up tilt correlate with younger age but not orthostatic symptoms.

Authors:  Colleen T Ives; Kurt Kimpinski
Journal:  J Appl Physiol (1985)       Date:  2013-06-13

8.  The Postural Tachycardia Syndrome (POTS): pathophysiology, diagnosis & management.

Authors:  Satish R Raj
Journal:  Indian Pacing Electrophysiol J       Date:  2006-04-01

9.  Orthostatic symptoms does not always manifest during tilt-table test in pediatric postural orthostatic tachycardia syndrome patients.

Authors:  Tae-Eon Huh; Jung Sook Yeom; Young-Soo Kim; Hyang-Ok Woo; Ji Sook Park; Eun Sil Park; Ji-Hyun Seo; Jae-Young Lim; Chan-Hoo Park; Ki-Jong Park; Hee-Shang Youn
Journal:  Korean J Pediatr       Date:  2013-01-29

10.  Patients with Orthostatic Intolerance: Relationship to Autonomic Function Tests results and Reproducibility of Symptoms on Tilt.

Authors:  Hyung Lee; Phillip A Low; Hyun Ah Kim
Journal:  Sci Rep       Date:  2017-07-18       Impact factor: 4.379

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  2 in total

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Authors:  Holly M Cline; Adam Einhardt
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2.  Prospective Evaluation of Autonomic Dysfunction in Post-Acute Sequela of COVID-19.

Authors:  Sameer M Jamal; David B Landers; Steven M Hollenberg; Zoltan G Turi; Taya V Glotzer; Jana Tancredi; Joseph E Parrillo
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  2 in total

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