Literature DB >> 33490268

Effectiveness and Safety of Posterior Vaginal Repair with Single-Incision, Ultralightweight, Monofilament Propylene Mesh: First Evidence from a Case Series with Short-Term Results.

Francesco Deltetto1, Alessandro Favilli2, Giovanni Buzzaccarini3, Amerigo Vitagliano4.   

Abstract

OBJECTIVE: The use of transvaginal mesh is controversial, and over time, multiple surgical methods for the treatment of posterior vaginal prolapse (PVP) have been proposed including different surgical approaches and techniques. To date, no clear conclusion has been reached about the use of mesh for reinforcing transvaginal posterior repair. The aim of this study was to evaluate the feasibility, safety, and effectiveness of a novel, ultralightweight mesh for the treatment of PVP.
METHODS: We performed a single-center, prospective observational study on consecutive patients referred for primary or recurrent, symptomatic stage II PVP (according to the international Pelvic Organ Prolapse Quantification System) from April 2017 to September 2018. In all patients, transvaginal posterior repair was augmented with a single-incision, isoelastic polypropylene mesh. Data about the postoperative outcomes were collected until December 2019.
RESULTS: A total number of 15 patients were included. The median follow-up after surgery was 18 months (IQR = 14). Surgery was completed in all cases without complications. Regarding the anatomical outcomes (as measured according to POP-q classification), a significant improvement was observed in terms of Bp, D, and C (p < 0.05). The functional outcomes were significantly ameliorated after surgery, with a reduction of bulge symptom, stypsis, incomplete evacuation, and excessive staining (p < 0.05). The quality of life was significantly improved in the majority of patients (p < 0.05). Median patients' satisfaction rate was 100% (IQR = 22.5%). Neither early nor late postoperative complications occurred.
CONCLUSIONS: Single-incision, ultralightweight polypropylene meshes were safe and highly effective in the treatment of PVP. As our study has some limitations, further large, controlled studies are needed.
Copyright © 2021 Francesco Deltetto et al.

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Year:  2021        PMID: 33490268      PMCID: PMC7801075          DOI: 10.1155/2021/3204145

Source DB:  PubMed          Journal:  Biomed Res Int            Impact factor:   3.411


  22 in total

1.  Re: Jean-Philippe Lucot, Michel Cosson, Georges Bader, et al. Safety of Vaginal Mesh Surgery Versus Laparoscopic Mesh Sacropexy for Cystocele Repair: Results of the Prosthetic Pelvic Floor Repair Randomized Controlled Trial. Eur Urol 2018;74:167-76: Is There Enough Evidence To Prove Higher Safety of Laparoscopic Sacropexy in Comparison to Vaginal Surgery for Cystocele Mesh Repair?

Authors:  Maurizio Bologna; Amerigo Vitagliano; Mauro Cervigni
Journal:  Eur Urol       Date:  2018-06-01       Impact factor: 20.096

2.  Pelvic organ prolapse.

Authors:  Indumathi Kuncharapu; Barbara A Majeroni; Dallas W Johnson
Journal:  Am Fam Physician       Date:  2010-05-01       Impact factor: 3.292

3.  Incidence and lifetime risk of pelvic organ prolapse surgery in Denmark from 1977 to 2009.

Authors:  Ea Løwenstein; Bent Ottesen; Helga Gimbel
Journal:  Int Urogynecol J       Date:  2014-05-20       Impact factor: 2.894

4.  The relationship of vaginal prolapse severity to symptoms and quality of life.

Authors:  G Alessandro Digesu; Charlotte Chaliha; Stefano Salvatore; Anna Hutchings; Vik Khullar
Journal:  BJOG       Date:  2005-07       Impact factor: 6.531

5.  Transvaginal treatment of anterior and apical genital prolapses using an Ultra lightweight mesh: Restorelle® Direct Fix™. A retrospective study on feasibility and morbidity.

Authors:  Philippe Ferry; Pauline Bertherat; Anne Gauthier; Richard Villet; Francesco Del Piano; David Hamid; Hervé Fernandez; Pierre-Louis Broux; Delphine Salet-Lizée; Etienne Vincens; Pierre Ntshaykolo; Philippe Debodinance; Philippe Pocholle; Yannick Thirouard; Renaud de Tayrac
Journal:  J Gynecol Obstet Hum Reprod       Date:  2018-06-18

6.  Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT).

Authors:  Cathryn Ma Glazener; Suzanne Breeman; Andrew Elders; Christine Hemming; Kevin G Cooper; Robert M Freeman; Anthony Rb Smith; Fiona Reid; Suzanne Hagen; Isobel Montgomery; Mary Kilonzo; Dwayne Boyers; Alison McDonald; Gladys McPherson; Graeme MacLennan; John Norrie
Journal:  Lancet       Date:  2016-12-21       Impact factor: 79.321

7.  Clinical effectiveness and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a comprehensive cohort study - results from the PROSPECT Study.

Authors:  Cathryn Glazener; Suzanne Breeman; Andrew Elders; Christine Hemming; Kevin Cooper; Robert Freeman; Anthony Smith; Suzanne Hagen; Isobel Montgomery; Mary Kilonzo; Dwayne Boyers; Alison McDonald; Gladys McPherson; Graeme MacLennan; John Norrie
Journal:  Health Technol Assess       Date:  2016-12       Impact factor: 4.014

8.  Pelvic Organ Prolapse Quantification System (POP-Q) - a new era in pelvic prolapse staging.

Authors:  C Persu; C R Chapple; V Cauni; S Gutue; P Geavlete
Journal:  J Med Life       Date:  2011-02-25

Review 9.  Current surgical management of pelvic organ prolapse: Strategies for the improvement of surgical outcomes.

Authors:  Kwang Jin Ko; Kyu-Sung Lee
Journal:  Investig Clin Urol       Date:  2019-10-29

10.  1-year outcome after treatment of uterovaginal prolapse with a 6-point fixation mesh.

Authors:  Andreas Brandt; Andrzej Kuszka; Achim Niesel; Henrik Lutz; Christian Fünfgeld; Mathias Mengel; Daniela Ulrich
Journal:  Neurourol Urodyn       Date:  2019-03-14       Impact factor: 2.696

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  1 in total

1.  The effect evaluation of traditional vaginal surgery and transvaginal mesh surgery for severe pelvic organ prolapse: 5 years follow-up.

Authors:  Ying-An Zhang; Wei Wang; Xiao-Li Li; Jie Pan; Zhao-Ai Li
Journal:  Open Med (Wars)       Date:  2022-04-22
  1 in total

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