Literature DB >> 33489622

Histopathological Coexistence of Extragenital Lichen Sclerosus and Morphea in a Single Lesion.

Reema R Almuqati1, Jehad Hariri2, Mohammed Abduljabbar2,1.   

Abstract

Lichen sclerosus (LS) and morphea are two infrequent inflammatory dermatoses of unknown etiology. LS is characterized by, polygonal, bluish-white, slightly elevated papules that coalesce into plaques, which become increasingly atrophic overtime.it mostly affects genitals, however, it can affect any site on the skin and mucosa. Morphea characterized by, erythematous to violaceous patches or plaque with a white, sclerotic center, and the outer edge of the lesions take on the characteristic violaceous ring. The overlapping clinical and histopathologic features of both LS and morphea in the same patient have led some to speculate that they may have a common pathologic link or that both conditions represent the same disease spectrum. The coexistence of LS and morphea in the same lesion is a rare finding. We present a patient, who was diagnosed with what appeared clinically to be extragenital LS, but with histopathologic features of both LS and morphea.
Copyright © 2020, Almuqati et al.

Entities:  

Keywords:  atrophy; coexistence; lichen sclerosus; morphea

Year:  2020        PMID: 33489622      PMCID: PMC7815259          DOI: 10.7759/cureus.12215

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  15 in total

1.  Low-dose ultraviolet A1 phototherapy for extragenital lichen sclerosus: results of a preliminary study.

Authors:  Alexander Kreuter; Thilo Gambichler; Annelies Avermaete; Marcus Happe; Martina Bacharach-Buhles; Klaus Hoffmann; Thomas Jansen; Peter Altmeyer; Gregor von Kobyletzki
Journal:  J Am Acad Dermatol       Date:  2002-02       Impact factor: 11.527

Review 2.  Update on morphea: part II. Outcome measures and treatment.

Authors:  Nicole Fett; Victoria P Werth
Journal:  J Am Acad Dermatol       Date:  2011-02       Impact factor: 11.527

Review 3.  Update on morphea: part I. Epidemiology, clinical presentation, and pathogenesis.

Authors:  Nicole Fett; Victoria P Werth
Journal:  J Am Acad Dermatol       Date:  2011-02       Impact factor: 11.527

Review 4.  Lichen Sclerosus-Presentation, Diagnosis and Management.

Authors:  Gudula Kirtschig
Journal:  Dtsch Arztebl Int       Date:  2016-05-13       Impact factor: 5.594

Review 5.  Lichen sclerosus.

Authors:  Ruth Murphy
Journal:  Dermatol Clin       Date:  2010-10       Impact factor: 3.478

6.  Generalized morphea, lichen sclerosis et atrophicus associated with oral submucosal fibrosis in an adult male.

Authors:  Sarvjit Kaur Virdi; Amrinder Jit Singh Kanwar
Journal:  Indian J Dermatol Venereol Leprol       Date:  2009 Jan-Feb       Impact factor: 2.545

Review 7.  Classification of morphea (localized scleroderma)

Authors:  L S Peterson; A M Nelson; W P Su
Journal:  Mayo Clin Proc       Date:  1995-11       Impact factor: 7.616

8.  Lichen sclerosus et atrophicus.

Authors:  Amy E Rose; Kevin P Boyd; Shane A Meehan; Jo-Ann Latkowski
Journal:  Dermatol Online J       Date:  2013-12-16

9.  Lichen sclerosus et atrophicus. A study of 76 cases and their relation to diabetes.

Authors:  B García-Bravo; P Sánchez-Pedreño; A Rodríguez-Pichardo; F Camacho
Journal:  J Am Acad Dermatol       Date:  1988-09       Impact factor: 11.527

10.  Distinct autoimmune syndromes in morphea: a review of 245 adult and pediatric cases.

Authors:  Justin J Leitenberger; Rachael L Cayce; Robert W Haley; Beverley Adams-Huet; Paul R Bergstresser; Heidi T Jacobe
Journal:  Arch Dermatol       Date:  2009-05
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  1 in total

1.  Usefulness of Dermoscopy in Localized Scleroderma (LoS, Morphea) Diagnosis and Assessment-Monocentric Cross-Sectional Study.

Authors:  Paulina Szczepanik-Kułak; Anna Michalak-Stoma; Dorota Krasowska
Journal:  J Clin Med       Date:  2022-01-30       Impact factor: 4.241

  1 in total

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