Literature DB >> 33489002

Machine learning applications in drug development.

Clémence Réda1,2, Emilie Kaufmann3, Andrée Delahaye-Duriez1,4,5.   

Abstract

Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of diseases and associated biological phenomena; help planning preclinical wet-lab experiments, and even future clinical trials. This automation of the drug development process might be key to the current issue of low productivity rate that pharmaceutical companies currently face. In this survey, we will particularly focus on two classes of methods: sequential learning and recommender systems, which are active biomedical fields of research.
© 2019 The Authors.

Entities:  

Keywords:  Adaptive clinical trial; Bayesian optimization; Collaborative filtering; Drug discovery; Drug repurposing; Multi-armed bandit

Year:  2019        PMID: 33489002      PMCID: PMC7790737          DOI: 10.1016/j.csbj.2019.12.006

Source DB:  PubMed          Journal:  Comput Struct Biotechnol J        ISSN: 2001-0370            Impact factor:   7.271


  64 in total

Review 1.  Drug discovery in pharmaceutical industry: productivity challenges and trends.

Authors:  Ish Khanna
Journal:  Drug Discov Today       Date:  2012-05-22       Impact factor: 7.851

Review 2.  Embracing the complexity of genomic data for personalized medicine.

Authors:  Mike West; Geoffrey S Ginsburg; Andrew T Huang; Joseph R Nevins
Journal:  Genome Res       Date:  2006-05       Impact factor: 9.043

3.  The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Authors:  Justin Lamb; Emily D Crawford; David Peck; Joshua W Modell; Irene C Blat; Matthew J Wrobel; Jim Lerner; Jean-Philippe Brunet; Aravind Subramanian; Kenneth N Ross; Michael Reich; Haley Hieronymus; Guo Wei; Scott A Armstrong; Stephen J Haggarty; Paul A Clemons; Ru Wei; Steven A Carr; Eric S Lander; Todd R Golub
Journal:  Science       Date:  2006-09-29       Impact factor: 47.728

4.  Predicting drug-disease associations and their therapeutic function based on the drug-disease association bipartite network.

Authors:  Wen Zhang; Xiang Yue; Feng Huang; Ruoqi Liu; Yanlin Chen; Chunyang Ruan
Journal:  Methods       Date:  2018-06-04       Impact factor: 3.608

5.  Assessing the Effectiveness of Causality Inference Methods for Gene Regulatory Networks.

Authors:  Syed Sazzad Ahmed; Swarup Roy; Jugal Kalita
Journal:  IEEE/ACM Trans Comput Biol Bioinform       Date:  2018-07-06       Impact factor: 3.710

6.  Bandit strategies evaluated in the context of clinical trials in rare life-threatening diseases.

Authors:  Sofía S Villar
Journal:  Probab Eng Inf Sci       Date:  2017-06-07       Impact factor: 1.269

7.  BioModels: ten-year anniversary.

Authors:  Vijayalakshmi Chelliah; Nick Juty; Ishan Ajmera; Raza Ali; Marine Dumousseau; Mihai Glont; Michael Hucka; Gaël Jalowicki; Sarah Keating; Vincent Knight-Schrijver; Audald Lloret-Villas; Kedar Nath Natarajan; Jean-Baptiste Pettit; Nicolas Rodriguez; Michael Schubert; Sarala M Wimalaratne; Yangyang Zhao; Henning Hermjakob; Nicolas Le Novère; Camille Laibe
Journal:  Nucleic Acids Res       Date:  2014-11-20       Impact factor: 16.971

8.  A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.

Authors:  Prashant K Srivastava; Jonathan van Eyll; Patrice Godard; Manuela Mazzuferi; Andree Delahaye-Duriez; Juliette Van Steenwinckel; Pierre Gressens; Benedicte Danis; Catherine Vandenplas; Patrik Foerch; Karine Leclercq; Georges Mairet-Coello; Alvaro Cardenas; Frederic Vanclef; Liisi Laaniste; Isabelle Niespodziany; James Keaney; Julien Gasser; Gaelle Gillet; Kirill Shkura; Seon-Ah Chong; Jacques Behmoaras; Irena Kadiu; Enrico Petretto; Rafal M Kaminski; Michael R Johnson
Journal:  Nat Commun       Date:  2018-09-03       Impact factor: 14.919

Review 9.  Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases.

Authors:  Ahmet Sureyya Rifaioglu; Heval Atas; Maria Jesus Martin; Rengul Cetin-Atalay; Volkan Atalay; Tunca Doğan
Journal:  Brief Bioinform       Date:  2019-09-27       Impact factor: 11.622

10.  The Comparative Toxicogenomics Database: update 2019.

Authors:  Allan Peter Davis; Cynthia J Grondin; Robin J Johnson; Daniela Sciaky; Roy McMorran; Jolene Wiegers; Thomas C Wiegers; Carolyn J Mattingly
Journal:  Nucleic Acids Res       Date:  2019-01-08       Impact factor: 16.971

View more
  18 in total

Review 1.  Machine Learning Techniques for Personalised Medicine Approaches in Immune-Mediated Chronic Inflammatory Diseases: Applications and Challenges.

Authors:  Junjie Peng; Elizabeth C Jury; Pierre Dönnes; Coziana Ciurtin
Journal:  Front Pharmacol       Date:  2021-09-30       Impact factor: 5.810

Review 2.  Application of Artificial Neural Networks in the Process Analytical Technology of Pharmaceutical Manufacturing-a Review.

Authors:  Brigitta Nagy; Dorián László Galata; Attila Farkas; Zsombor Kristóf Nagy
Journal:  AAPS J       Date:  2022-06-14       Impact factor: 3.603

3.  Non-linearity of Metabolic Pathways Critically Influences the Choice of Machine Learning Model.

Authors:  Ophélie Lo-Thong-Viramoutou; Philippe Charton; Xavier F Cadet; Brigitte Grondin-Perez; Emma Saavedra; Cédric Damour; Frédéric Cadet
Journal:  Front Artif Intell       Date:  2022-06-10

4.  Data science in unveiling COVID-19 pathogenesis and diagnosis: evolutionary origin to drug repurposing.

Authors:  Jayanta Kumar Das; Giuseppe Tradigo; Pierangelo Veltri; Pietro H Guzzi; Swarup Roy
Journal:  Brief Bioinform       Date:  2021-03-22       Impact factor: 11.622

5.  Utilizing graph machine learning within drug discovery and development.

Authors:  Thomas Gaudelet; Ben Day; Arian R Jamasb; Jyothish Soman; Cristian Regep; Gertrude Liu; Jeremy B R Hayter; Richard Vickers; Charles Roberts; Jian Tang; David Roblin; Tom L Blundell; Michael M Bronstein; Jake P Taylor-King
Journal:  Brief Bioinform       Date:  2021-11-05       Impact factor: 11.622

6.  Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures.

Authors:  Sepehr Golriz Khatami; Sarah Mubeen; Vinay Srinivas Bharadhwaj; Alpha Tom Kodamullil; Martin Hofmann-Apitius; Daniel Domingo-Fernández
Journal:  NPJ Syst Biol Appl       Date:  2021-10-27

7.  Evolving scenario of big data and Artificial Intelligence (AI) in drug discovery.

Authors:  Manish Kumar Tripathi; Abhigyan Nath; Tej P Singh; A S Ethayathulla; Punit Kaur
Journal:  Mol Divers       Date:  2021-06-23       Impact factor: 3.364

8.  Special issue of molecular diversity on "AI and ML for small molecule drug discovery in the big data era".

Authors:  Kunal Roy
Journal:  Mol Divers       Date:  2021-08       Impact factor: 3.364

Review 9.  Utility of Artificial Intelligence Amidst the COVID 19 Pandemic: A Review.

Authors:  Agam Bansal; Rana Prathap Padappayil; Chandan Garg; Anjali Singal; Mohak Gupta; Allan Klein
Journal:  J Med Syst       Date:  2020-08-01       Impact factor: 4.460

10.  AI in drug development: a multidisciplinary perspective.

Authors:  Víctor Gallego; Roi Naveiro; Carlos Roca; David Ríos Insua; Nuria E Campillo
Journal:  Mol Divers       Date:  2021-07-12       Impact factor: 3.364

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.