Literature DB >> 3348747

Effect of ammonium chloride on the multiplication of infectious pancreatic necrosis virus.

G Farías1, E Navarrete, J Kiss, J Kuznar.   

Abstract

The multiplication of IPNV in CHSE cells is inhibited by ammonium chloride. This inhibition is complete if NH4Cl is added early in the infective cycle. Immunofluorescence analysis shows that NH4Cl reduces the number of virus producing cells and thus suggests it may act by inhibiting virus internalization. In addition, NH4Cl can produce partial inhibition of IPNV multiplication if added later in the replicative cycle. Analysis of 3H-uridine incorporation into viral RNA shows that this later effect could be an inhibition of viral RNA synthesis.

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Year:  1988        PMID： 3348747     DOI： 10.1007/bf01322165

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  11 in total

1.  Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

Authors:  S Ohkuma; B Poole
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

Review 2.  The molecular biology of infectious pancreatic necrosis virus: a review.

Authors:  P Dobos; T E Roberts
Journal:  Can J Microbiol       Date:  1983-04       Impact factor: 2.419

3.  Identity between infectious pancreatic necrosis virus VR-299 and a Chilean isolate.

Authors:  E Espinoza; G Farías; M Soler; J Kuznar
Journal:  Intervirology       Date:  1985       Impact factor: 1.763

4.  Role of vesicles during adenovirus 2 internalization into HeLa cells.

Authors:  U Svensson
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

5.  Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells.

Authors:  W M Canning; B N Fields
Journal:  Science       Date:  1983-02-25       Impact factor: 47.728

6.  Inhibition of multiplication of herpes simplex virus type 1 by ammonium chloride and chloroquine.

Authors:  A H Koyama; T Uchida
Journal:  Virology       Date:  1984-10-30       Impact factor: 3.616

7.  Effects of lysosomotropic weak bases on infection of BHK-21 cells by Sindbis virus.

Authors:  S Cassell; J Edwards; D T Brown
Journal:  J Virol       Date:  1984-12       Impact factor: 5.103

8.  Virus-specific protein synthesis in cells infected by infectious pancreatic necrosis virus.

Authors:  P Dobos
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103

9.  On the entry of Semliki forest virus into BHK-21 cells.

Authors:  A Helenius; J Kartenbeck; K Simons; E Fries
Journal:  J Cell Biol       Date:  1980-02       Impact factor: 10.539

10.  Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH.

Authors:  I H Madshus; S Olsnes; K Sandvig
Journal:  J Cell Biol       Date:  1984-04       Impact factor: 10.539
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  5 in total

1.  Stability of Minimum Essential Medium functionality despite L-glutamine decomposition.

Authors:  Maja Jagušić; Dubravko Forčić; Marija Brgles; Leonida Kutle; Maja Šantak; Mladen Jergović; Ljerka Kotarski; Krešo Bendelja; Beata Halassy
Journal:  Cytotechnology       Date:  2015-04-24       Impact factor: 2.058

2.  Attachment and entry of infectious pancreatic necrosis virus (IPNV) into CHSE-214 cells.

Authors:  J Kuznar; M Soler; G Farias; J C Espinoza
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

3.  Rift Valley fever virus Gn V5-epitope tagged virus enables identification of UBR4 as a Gn interacting protein that facilitates Rift Valley fever virus production.

Authors:  Nicole Bracci; Cynthia de la Fuente; Sahar Saleem; Chelsea Pinkham; Aarthi Narayanan; Adolfo García-Sastre; Velmurugan Balaraman; Juergen A Richt; William Wilson; Kylene Kehn-Hall
Journal:  Virology       Date:  2022-01-07       Impact factor: 3.616

4.  Adenovirus uncoating and nuclear establishment are not affected by weak base amines.

Authors:  E Rodríguez; E Everitt
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

5.  Vaporization, bioactive formulations and a marine natural product: different perspectives on antivirals.

Authors:  Thomas J Manning; Jenu Thomas-Richardson; Matthew Cowan; Torien Beard
Journal:  Drug Discov Today       Date:  2020-04-20       Impact factor: 7.851
  5 in total

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