Literature DB >> 33483897

The Impact of a Mobile Gaming Intervention to Increase Adherence to Pre-exposure Prophylaxis.

Laura Whiteley1, Lacey Craker2, Kayla K Haubrick2, Trisha Arnold3, Leandro Mena4,5, Elizabeth Olsen3, Larry K Brown3,2.   

Abstract

Pre-exposure prophylaxis is effective in preventing HIV, but data show that its effectiveness is compromised by suboptimal adherence. This randomized controlled trial (n = 69) tested the impact of an iPhone game, Viral Combat, on PrEP adherence over 24 weeks. Tenofovir-diphosphate in red blood cells was collected as a biological outcome of adherence. At 24-weeks, intervention participants were 3.75 (95% CI: 1.20-11.77; p = 0.02) times as likely to engage in optimal PrEP dosing compared to controls. Viral Combat showed preliminary efficacy in improving PrEP adherence for diverse young men who have sex with men.

Entities:  

Keywords:  Adherence; Men who have sex with men (MSM); Mobile technology intervention; Pre-exposure prophylaxis (PrEP)

Mesh：

Substances：

Year:  2021        PMID： 33483897      PMCID： PMC8085097          DOI： 10.1007/s10461-020-03118-3

Source DB:  PubMed          Journal:  AIDS Behav        ISSN： 1090-7165


  13 in total

1.  An information-motivation-behavioral skills model of adherence to antiretroviral therapy.

Authors:  Jeffrey D Fisher; William A Fisher; K Rivet Amico; Jennifer J Harman
Journal:  Health Psychol       Date:  2006-07       Impact factor: 4.267

Review 2.  Addressing engagement in technology-based behavioural HIV interventions through paradata metrics.

Authors:  José A Bauermeister; Jesse M Golinkoff; Kathryn E Muessig; Keith J Horvath; Lisa B Hightow-Weidman
Journal:  Curr Opin HIV AIDS       Date:  2017-09       Impact factor: 4.283

3.  Predictors of medication adherence in high risk youth of color living with HIV.

Authors:  Karen E Macdonell; Sylvie Naar-King; Debra A Murphy; Jeffrey T Parsons; Gary W Harper
Journal:  J Pediatr Psychol       Date:  2009-09-15

Review 4.  The future of digital games for HIV prevention and care.

Authors:  Lisa B Hightow-Weidman; Kathryn E Muessig; José A Bauermeister; Sara LeGrand; Lynn E Fiellin
Journal:  Curr Opin HIV AIDS       Date:  2017-09       Impact factor: 4.283

5.  Development and psychometric evaluation of the brief HIV Knowledge Questionnaire.

Authors:  Michael P Carey; Kerstin E E Schroder
Journal:  AIDS Educ Prev       Date:  2002-04

6.  Tenofovir, emtricitabine, and tenofovir diphosphate in dried blood spots for determining recent and cumulative drug exposure.

Authors:  Jose R Castillo-Mancilla; Jia-Hua Zheng; Joseph E Rower; Amie Meditz; Edward M Gardner; Julie Predhomme; Caitlin Fernandez; Jacob Langness; Jennifer J Kiser; Lane R Bushman; Peter L Anderson
Journal:  AIDS Res Hum Retroviruses       Date:  2012-10-10       Impact factor: 2.205

7.  Psychiatric disorders and sexual risk among adolescents in mental health treatment.

Authors:  Larry K Brown; Wendy Hadley; Angela Stewart; Celia Lescano; Laura Whiteley; Geri Donenberg; Ralph DiClemente
Journal:  J Consult Clin Psychol       Date:  2010-08

8.  Predictors of Over-Reporting HIV Pre-exposure Prophylaxis (PrEP) Adherence Among Young Men Who Have Sex With Men (YMSM) in Self-Reported Versus Biomarker Data.

Authors:  Zoë Baker; Marjan Javanbakht; Stan Mierzwa; Craig Pavel; Michelle Lally; Gregory Zimet; Pamina Gorbach
Journal:  AIDS Behav       Date:  2018-04

9.  A systematic review of adherence to oral pre-exposure prophylaxis for HIV - how can we improve uptake and adherence?

Authors:  David Sidebottom; Anna Mia Ekström; Susanne Strömdahl
Journal:  BMC Infect Dis       Date:  2018-11-16       Impact factor: 3.090

10.  A Mobile Gaming Intervention for Persons on Pre-Exposure Prophylaxis: Protocol for Intervention Development and Randomized Controlled Trial.

Authors:  Laura Whiteley; Elizabeth Olsen; Leandro Mena; Kayla Haubrick; Lacey Craker; Dylan Hershkowitz; Larry K Brown
Journal:  JMIR Res Protoc       Date:  2020-09-14
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  3 in total

Review 1.  Evidence and implication of interventions across various socioecological levels to address pre-exposure prophylaxis uptake and adherence among men who have sex with men in the United States: a systematic review.

Authors:  Ying Wang; Jason W Mitchell; Chen Zhang; Yu Liu
Journal:  AIDS Res Ther       Date:  2022-06-26       Impact factor: 2.846

Review 2.  Using Video Games to Improve the Sexual Health of Young People Aged 15 to 25 Years: Rapid Review.

Authors:  Ignacio Franco Vega; Anastasia Eleftheriou; Cynthia Graham
Journal:  JMIR Serious Games       Date:  2022-05-19       Impact factor: 3.364

3.  Feasibility, Acceptability, and Preliminary Efficacy of a Gamified Mobile Health Contingency Management Intervention for PrEP Adherence Among Black MSM.

Authors:  John T Mitchell; Charles M Burns; Breyah Atkinson; Mackenzie Cottrell; Justin K Frye; Mehri S McKellar; Angela D M Kashuba; F Joseph McClernon; Nwora Lance Okeke
Journal:  AIDS Behav       Date:  2022-04-13
  3 in total

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