Literature DB >> 33483543

INSPECTOR: free software for magnetic resonance spectroscopy data inspection, processing, simulation and analysis.

Martin Gajdošík1, Karl Landheer2, Kelley M Swanberg2, Christoph Juchem2,3.   

Abstract

In vivo magnetic resonance spectroscopy (MRS) is a powerful tool for biomedical research and clinical diagnostics, allowing for non-invasive measurement and analysis of small molecules from living tissues. However, currently available MRS processing and analytical software tools are limited in their potential for in-depth quality management, access to details of the processing stream, and user friendliness. Moreover, available MRS software focuses on selected aspects of MRS such as simulation, signal processing or analysis, necessitating the use of multiple packages and interfacing among them for biomedical applications. The freeware INSPECTOR comprises enhanced MRS data processing, simulation and analytical capabilities in a one-stop-shop solution for a wide range of biomedical research and diagnostic applications. Extensive data handling, quality management and visualization options are built in, enabling the assessment of every step of the processing chain with maximum transparency. The parameters of the processing can be flexibly chosen and tailored for the specific research problem, and extended confidence information is provided with the analysis. The INSPECTOR software stands out in its user-friendly workflow and potential for automation. In addition to convenience, the functionalities of INSPECTOR ensure rigorous and consistent data processing throughout multi-experiment and multi-center studies.

Entities:  

Year:  2021        PMID: 33483543     DOI: 10.1038/s41598-021-81193-9

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  6 in total

1.  Concentration and effective T2 relaxation times of macromolecules at 3T.

Authors:  Karl Landheer; Martin Gajdošík; Michael Treacy; Christoph Juchem
Journal:  Magn Reson Med       Date:  2020-05-19       Impact factor: 4.668

2.  A semi-LASER, single-voxel spectroscopic sequence with a minimal echo time of 20.1 ms in the human brain at 3 T.

Authors:  Karl Landheer; Martin Gajdošík; Christoph Juchem
Journal:  NMR Biomed       Date:  2020-06-18       Impact factor: 4.044

Review 3.  Magnetic resonance spectroscopy studies of GABA in neuropsychiatric disorders.

Authors:  Linda Chang; Christine C Cloak; Thomas Ernst
Journal:  J Clin Psychiatry       Date:  2003       Impact factor: 4.384

4.  Across-vendor standardization of semi-LASER for single-voxel MRS at 3T.

Authors:  Dinesh K Deelchand; Adam Berrington; Ralph Noeske; James M Joers; Arvin Arani; Joseph Gillen; Michael Schär; Jon-Fredrik Nielsen; Scott Peltier; Navid Seraji-Bozorgzad; Karl Landheer; Christoph Juchem; Brian J Soher; Douglas C Noll; Kejal Kantarci; Eva M Ratai; Thomas H Mareci; Peter B Barker; Gülin Öz
Journal:  NMR Biomed       Date:  2019-12-18       Impact factor: 4.044

5.  Contribution of macromolecules to brain 1 H MR spectra: Experts' consensus recommendations.

Authors:  Cristina Cudalbu; Kevin L Behar; Pallab K Bhattacharyya; Wolfgang Bogner; Tamas Borbath; Robin A de Graaf; Rolf Gruetter; Anke Henning; Christoph Juchem; Roland Kreis; Phil Lee; Hongxia Lei; Małgorzata Marjańska; Ralf Mekle; Saipavitra Murali-Manohar; Michal Považan; Veronika Rackayová; Dunja Simicic; Johannes Slotboom; Brian J Soher; Zenon Starčuk; Jana Starčuková; Ivan Tkáč; Stephen Williams; Martin Wilson; Andrew Martin Wright; Lijing Xin; Vladimír Mlynárik
Journal:  NMR Biomed       Date:  2020-11-25       Impact factor: 4.044

6.  Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts' consensus recommendations.

Authors:  Roland Kreis; Vincent Boer; In-Young Choi; Cristina Cudalbu; Robin A de Graaf; Charles Gasparovic; Arend Heerschap; Martin Krššák; Bernard Lanz; Andrew A Maudsley; Martin Meyerspeer; Jamie Near; Gülin Öz; Stefan Posse; Johannes Slotboom; Melissa Terpstra; Ivan Tkáč; Martin Wilson; Wolfgang Bogner
Journal:  NMR Biomed       Date:  2020-08-17       Impact factor: 4.044

  6 in total
  5 in total

1.  Comparison of different linear-combination modeling algorithms for short-TE proton spectra.

Authors:  Helge J Zöllner; Michal Považan; Steve C N Hui; Sofie Tapper; Richard A E Edden; Georg Oeltzschner
Journal:  NMR Biomed       Date:  2021-02-02       Impact factor: 4.044

2.  Comparison of seven modelling algorithms for γ-aminobutyric acid-edited proton magnetic resonance spectroscopy.

Authors:  Alexander R Craven; Pallab K Bhattacharyya; William T Clarke; Ulrike Dydak; Richard A E Edden; Lars Ersland; Pravat K Mandal; Mark Mikkelsen; James B Murdoch; Jamie Near; Reuben Rideaux; Deepika Shukla; Min Wang; Martin Wilson; Helge J Zöllner; Kenneth Hugdahl; Georg Oeltzschner
Journal:  NMR Biomed       Date:  2022-02-23       Impact factor: 4.478

3.  Multiple sclerosis diagnosis and phenotype identification by multivariate classification of in vivo frontal cortex metabolite profiles.

Authors:  Kelley M Swanberg; Abhinav V Kurada; Hetty Prinsen; Christoph Juchem
Journal:  Sci Rep       Date:  2022-08-16       Impact factor: 4.996

Review 4.  Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications.

Authors:  Duanghathai Pasanta; Khin Thandar Htun; Jie Pan; Montree Tungjai; Siriprapa Kaewjaeng; Hongjoo Kim; Jakrapong Kaewkhao; Suchart Kothan
Journal:  Diagnostics (Basel)       Date:  2021-05-07

5.  In Vitro 31P MR Chemical Shifts of In Vivo-Detectable Metabolites at 3T as a Basis Set for a Pilot Evaluation of Skeletal Muscle and Liver 31P Spectra with LCModel Software.

Authors:  Petr Sedivy; Tereza Dusilova; Milan Hajek; Martin Burian; Martin Krššák; Monika Dezortova
Journal:  Molecules       Date:  2021-12-14       Impact factor: 4.411

  5 in total

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