Literature DB >> 33481181

Triterpenoids from Walsura trichostemon.

Alfarius Eko Nugroho1, Yusuke Hirasawa1, Toshio Kaneda1, Osamu Shirota2, Michiyo Matsuno3, Hajime Mizukami3, Hiroshi Morita4.   

Abstract

Bioactivity guided separation of Walsura trichostemon stem methanolic extract led to the isolation of four new dammarane (1-4) and two new apotirucallane triterpenoids (5-6), together with one limonoid (7), 11,25-dideacetyltrichostemonate, 12β, 20S, 24R-trihydroxydammar-25-en-3-one and 12β, 20S, 25-trihydroxydammar-23-en-3-one. Compounds 1-7 showed in vitro inhibitory activity on the proliferation of A549, human lung adenocarcinoma cell line.

Entities:  

Keywords:  Apotirucallane; Cytotoxic activity; Dammarane; Meliaceae; Triterpenoid; Walsura trichostemon

Year:  2021        PMID： 33481181     DOI： 10.1007/s11418-021-01483-4

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  2 in total

1.  A new cytotoxic tirucallane from the twigs of Walsura trichostemon.

Authors:  Jirapast Sichaem; Pongpun Siripong; Santi Tip-Pyang; Jatuporn Phaopongthai
Journal:  Nat Prod Commun       Date:  2014-03       Impact factor: 0.986

2.  Cytotoxic triterpenoids from the stem bark of Aglaia angustifolia.

Authors:  Ricson Pemimpin Hutagaol; Desi Harneti; Agus Safari; Ace Tatang Hidayat; Unang Supratman; Khalijah Awang; Yoshihito Shiono
Journal:  J Asian Nat Prod Res       Date:  2020-06-13       Impact factor: 1.569
  2 in total
  1 in total

1.  Chukranoids A-I, isopimarane diterpenoids from Chukrasia velutina.

Authors:  Alfarius Eko Nugroho; Masaki Tange; Sumi Kusakabe; Yusuke Hirasawa; Osamu Shirota; Michiyo Matsuno; Hajime Mizukami; Takahiro Tougan; Toshihiro Horii; Hiroshi Morita
Journal:  J Nat Med       Date:  2022-05-05       Impact factor: 3.192
  1 in total

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