Literature DB >> 33479065

A practical review of functional neurological disorder (FND) for the general physician.

Karina Bennett1, Clare Diamond2, Ingrid Hoeritzauer1, Paula Gardiner2, Laura McWhirter2, Alan Carson2, Jon Stone2.   

Abstract

We present a practical overview of functional neurological disorder (FND), its epidemiology, assessment and diagnosis, diagnostic pitfalls, treatment, aetiology and mechanism. We present an update on functional limb weakness, tremor, dystonia and other abnormal movements, dissociative seizures, functional cognitive symptoms and urinary retention, and 'scan-negative' cauda equina syndrome. The diagnosis of FND should rest on clear positive evidence, typically from a combination of physical signs on examination or the nature of seizures. In treatment of FND, clear communication of the diagnosis and the involvement of the multidisciplinary team is beneficial. We recommend that patients with FND are referred to specialists with expertise in neurological diagnosis. FND is a common presentation in emergency and acute medical settings and there are many practical elements to making a positive diagnosis and communication which are useful for all physicians to be familiar with. © Royal College of Physicians 2021. All rights reserved.

Entities:  

Keywords:  conversion disorder; dissociative seizures,; functional neurological disorder; treatment

Mesh:

Year:  2021        PMID: 33479065      PMCID: PMC7850207          DOI: 10.7861/clinmed.2020-0987

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  45 in total

Review 1.  Isolated urinary retention in young women, or Fowler's syndrome.

Authors:  M J Swinn; C J Fowler
Journal:  Clin Auton Res       Date:  2001-10       Impact factor: 4.435

2.  Occupational therapy consensus recommendations for functional neurological disorder.

Authors:  Clare Nicholson; Mark J Edwards; Alan J Carson; Paula Gardiner; Dawn Golder; Kate Hayward; Susan Humblestone; Helen Jinadu; Carrie Lumsden; Julie MacLean; Lynne Main; Lindsey Macgregor; Glenn Nielsen; Louise Oakley; Jason Price; Jessica Ranford; Jasbir Ranu; Ed Sum; Jon Stone
Journal:  J Neurol Neurosurg Psychiatry       Date:  2020-07-30       Impact factor: 10.154

Review 3.  Complex regional pain syndrome and functional neurological disorders - time for reconciliation.

Authors:  Stoyan Popkirov; Ingrid Hoeritzauer; Lesley Colvin; Alan J Carson; Jon Stone
Journal:  J Neurol Neurosurg Psychiatry       Date:  2018-10-24       Impact factor: 10.154

4.  Do observer and self-reports of ictal eye closure predict psychogenic nonepileptic seizures?

Authors:  Tanvir U Syed; Ahsan M Arozullah; Gabriel P Suciu; Julia Toub; Hyunmi Kim; Michelle L Dougherty; Tim Wehner; Andrey Stojic; Ishtiaq Syed; Andreas V Alexopoulos
Journal:  Epilepsia       Date:  2007-12-06       Impact factor: 5.864

5.  Internet-based self-help randomized trial for motor functional neurologic disorder (SHIFT).

Authors:  Jeannette M Gelauff; Judith G M Rosmalen; Alan Carson; Joke M Dijk; Martijn Ekkel; Glenn Nielsen; Jon Stone; Marina A J Tijssen
Journal:  Neurology       Date:  2020-07-20       Impact factor: 9.910

6.  Dual diagnosis of epilepsy and psychogenic nonepileptic seizures: Systematic review and meta-analysis of frequency, correlates, and outcomes.

Authors:  Mansur A Kutlubaev; Ying Xu; Maree L Hackett; Jon Stone
Journal:  Epilepsy Behav       Date:  2018-10-29       Impact factor: 2.937

Review 7.  Stress and functional neurological disorders: mechanistic insights.

Authors:  Roxanne C Keynejad; Thomas Frodl; Richard Kanaan; Carmine Pariante; Markus Reuber; Timothy R Nicholson
Journal:  J Neurol Neurosurg Psychiatry       Date:  2018-11-08       Impact factor: 10.154

8.  Physiotherapy for functional motor disorders: a consensus recommendation.

Authors:  Glenn Nielsen; Jon Stone; Audrey Matthews; Melanie Brown; Chris Sparkes; Ross Farmer; Lindsay Masterton; Linsey Duncan; Alisa Winters; Laura Daniell; Carrie Lumsden; Alan Carson; Anthony S David; Mark Edwards
Journal:  J Neurol Neurosurg Psychiatry       Date:  2014-11-28       Impact factor: 10.154

9.  Incidence and outcome of functional stroke mimics admitted to a hyperacute stroke unit.

Authors:  Sergios Gargalas; Robert Weeks; Najma Khan-Bourne; Paul Shotbolt; Sara Simblett; Leah Ashraf; Claire Doyle; Victoria Bancroft; Anthony S David
Journal:  J Neurol Neurosurg Psychiatry       Date:  2015-08-28       Impact factor: 10.154

Review 10.  Functional cognitive disorder: dementia's blind spot.

Authors:  Harriet A Ball; Laura McWhirter; Clive Ballard; Rohan Bhome; Daniel J Blackburn; Mark J Edwards; Stephen M Fleming; Nick C Fox; Robert Howard; Jonathan Huntley; Jeremy D Isaacs; Andrew J Larner; Timothy R Nicholson; Catherine M Pennington; Norman Poole; Gary Price; Jason P Price; Markus Reuber; Craig Ritchie; Martin N Rossor; Jonathan M Schott; Tiago Teodoro; Annalena Venneri; Jon Stone; Alan J Carson
Journal:  Brain       Date:  2020-10-01       Impact factor: 13.501

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  6 in total

1.  Finding your own way to manage patients with functional disorders.

Authors:  Anton Emmanuel
Journal:  Clin Med (Lond)       Date:  2021-01       Impact factor: 2.659

2.  A guide to functional disease for a trauma conscious generation.

Authors:  Andrew Whitfield
Journal:  Clin Med (Lond)       Date:  2021-09       Impact factor: 5.410

3.  Opinion, knowledge, and clinical experience with functional neurological disorders among Italian neurologists: results from an online survey.

Authors:  Michele Tinazzi; Mirta Fiorio; Alfredo Berardelli; Bruno Bonetti; Domenico Marco Bonifati; Alessandro Burlina; Annachiara Cagnin; Francesca Calabria; Maurizio Corbetta; Pietro Cortelli; Bruno Giometto; Silvia Vittoria Guidoni; Leonardo Lopiano; Gianluigi Mancardi; Fabio Marchioretto; Maria Pellegrini; Francesco Teatini; Gioacchino Tedeschi; Lucia Tesolin; Emanuele Turinese; Mario Zappia; Angela Marotta
Journal:  J Neurol       Date:  2021-10-19       Impact factor: 6.682

4.  Functional Neurological Symptom Disorder (FND) Leading to the Development of Deep Vein Thrombosis (DVT).

Authors:  Ahmad Othman; Arthur Cecchini; Amira Eftaiha; Nneka Nwosisi; Deidre Pierce
Journal:  Cureus       Date:  2022-06-27

5.  Case report on psychogenic nonepileptic seizures: A series of unfortunate events.

Authors:  Aniebiot-Abasi Udofia; Tamarie Rocke
Journal:  Clin Case Rep       Date:  2022-10-11

Review 6.  The factitious/malingering continuum and its burden on public health costs: a review and experience in an Italian neurology setting.

Authors:  Marco Onofrj; Anna Digiovanni; Paola Ajdinaj; Mirella Russo; Claudia Carrarini; Massimo Di Giannantonio; Giovanni Martinotti; Stefano L Sensi
Journal:  Neurol Sci       Date:  2021-08-04       Impact factor: 3.307

  6 in total

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