Literature DB >> 33478141

Long Non-Coding RNAs (lncRNAs) in Cardiovascular Disease Complication of Type 2 Diabetes.

Nurruzanna Ismail1, Noraidatulakma Abdullah1, Nor Azian Abdul Murad1, Rahman Jamal1, Siti Aishah Sulaiman1.   

Abstract

The discovery of non-coding RNAs (ncRNAs) has opened a new paradigm to use ncRNAs as biomarkers to detect disease progression. Long non-coding RNAs (lncRNA) have garnered the most attention due to their specific cell-origin and their existence in biological fluids. Type 2 diabetes patients will develop cardiovascular disease (CVD) complications, and CVD remains the top risk factor for mortality. Understanding the lncRNA roles in T2D and CVD conditions will allow the future use of lncRNAs to detect CVD complications before the symptoms appear. This review aimed to discuss the roles of lncRNAs in T2D and CVD conditions and their diagnostic potential as molecular biomarkers for CVD complications in T2D.

Entities:  

Keywords:  biomarker; cardiovascular disease; diagnosis; insulin secretion; long noncoding RNA; type 2 diabetes

Year:  2021        PMID： 33478141      PMCID： PMC7835902          DOI： 10.3390/diagnostics11010145

Source DB:  PubMed          Journal:  Diagnostics (Basel)        ISSN： 2075-4418


  191 in total

1.  Unraveling the Expression Profiles of Long Noncoding RNAs in Rat Cardiac Hypertrophy and Functions of lncRNA BC088254 in Cardiac Hypertrophy Induced by Transverse Aortic Constriction.

Authors:  Xiaoying Li; Lei Zhang; Jiangjiu Liang
Journal:  Cardiology       Date:  2016-02-27       Impact factor: 1.869

2.  Long noncoding RNA LINC00968 promotes endothelial cell proliferation and migration via regulating miR-9-3p expression.

Authors:  Xiaofeng Wang; Zheng Zhao; Wei Zhang; Yi Wang
Journal:  J Cell Biochem       Date:  2018-11-28       Impact factor: 4.429

3.  Downregulation of HOTTIP regulates insulin secretion and cell cycle in islet β cells via inhibiting MEK/ERK pathway.

Authors:  X Xu; J Tian; Q-Y Li
Journal:  Eur Rev Med Pharmacol Sci       Date:  2018-08       Impact factor: 3.507

4.  MIAT promotes proliferation and hinders apoptosis by modulating miR-181b/STAT3 axis in ox-LDL-induced atherosclerosis cell models.

Authors:  Xiaoming Zhong; Xiang Ma; Lei Zhang; Yanming Li; Yunwei Li; Ruili He
Journal:  Biomed Pharmacother       Date:  2017-11-10       Impact factor: 6.529

5.  Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.

Authors:  Kyoko L Yap; Side Li; Ana M Muñoz-Cabello; Selina Raguz; Lei Zeng; Shiraz Mujtaba; Jesús Gil; Martin J Walsh; Ming-Ming Zhou
Journal:  Mol Cell       Date:  2010-06-11       Impact factor: 17.970

6.  ANRIL expression is associated with atherosclerosis risk at chromosome 9p21.

Authors:  Lesca M Holdt; Frank Beutner; Markus Scholz; Stephan Gielen; Gábor Gäbel; Hendrik Bergert; Gerhard Schuler; Joachim Thiery; Daniel Teupser
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-01-07       Impact factor: 8.311

7.  Long noncoding RNAs in patients with acute myocardial infarction.

Authors:  Mélanie Vausort; Daniel R Wagner; Yvan Devaux
Journal:  Circ Res       Date:  2014-07-17       Impact factor: 17.367

8.  A long noncoding RNA protects the heart from pathological hypertrophy.

Authors:  Wei Li; Chiou-Hong Lin; Pei Han; Jin Yang; Ching Shang; Sylvia T Nuernberg; Kevin Kai Jin; Weihong Xu; Chieh-Yu Lin; Chien-Jung Lin; Yiqin Xiong; Huanchieh Chien; Bin Zhou; Euan Ashley; Daniel Bernstein; Peng-Sheng Chen; Huei-Sheng Vincent Chen; Thomas Quertermous; Ching-Pin Chang
Journal:  Nature       Date:  2014-08-10       Impact factor: 49.962

Review 9.  Cardiac Remodeling: Concepts, Clinical Impact, Pathophysiological Mechanisms and Pharmacologic Treatment.

Authors:  Paula S Azevedo; Bertha F Polegato; Marcos F Minicucci; Sergio A R Paiva; Leonardo A M Zornoff
Journal:  Arq Bras Cardiol       Date:  2015-12-08       Impact factor: 2.000

Review 10.  Interactions Among Non-Coding RNAs in Diabetic Nephropathy.

Authors:  Tamil Selvi Loganathan; Siti Aishah Sulaiman; Nor Azian Abdul Murad; Shamsul Azhar Shah; Abdul Halim Abdul Gafor; Rahman Jamal; Noraidatulakma Abdullah
Journal:  Front Pharmacol       Date:  2020-03-03       Impact factor: 5.810
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  2 in total

Review 1.  Novel Cardiovascular Risk Factors in Patients with Diabetic Kidney Disease.

Authors:  Christodoula Kourtidou; Maria Stangou; Smaragdi Marinaki; Konstantinos Tziomalos
Journal:  Int J Mol Sci       Date:  2021-10-17       Impact factor: 5.923

2.  Association of Angio-LncRNAs MIAT rs1061540/MALAT1 rs3200401 Molecular Variants with Gensini Score in Coronary Artery Disease Patients Undergoing Angiography.

Authors:  Mohamed Y Elwazir; Mohammad H Hussein; Eman A Toraih; Essam Al Ageeli; Safya E Esmaeel; Manal S Fawzy; Salwa Faisal
Journal:  Biomolecules       Date:  2022-01-15
  2 in total

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