Literature DB >> 33469049

Integrated photothermal decontamination device for N95 respirators.

Marcelo Muñoz1,2, Maxime Comtois-Bona1,3, David Cortes1,3, Cagla Eren Cimenci1,4, Qiujiang Du5, Collin Thompson6, Juan David Figueroa1, Vivian Franklin7, Peter Liu5, Emilio I Alarcon8,9.   

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions. The COVID-19 pandemic has also resulted in a shortage of personal protective equipment (PPE) in many regions around the world, particularly in middle- and low-income countries. The shortages of PPE, such as N95 respirators, is something that will persist until an effective vaccine is made available. Thus, devices that while being easy to operate can also be rapidly deployed in health centers, and long-term residences without the need for major structural overhaul are instrumental to sustainably use N95 respirators. In this report, we present the design and validation of a decontamination device that combines UV-C & B irradiation with mild-temperature treatment. The device can decontaminate up to 20 masks in a cycle of < 30 min. The decontamination process did not damage or reduce the filtering capacity of the masks. Further, the efficacy of the device to eliminate microbes and viruses from the masks was also evaluated. The photothermal treatment of our device was capable of eradicating > 99.9999% of the bacteria and > 99.99% of the virus tested.

Entities:  

Year:  2021        PMID: 33469049      PMCID: PMC7815715          DOI: 10.1038/s41598-020-80908-8

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  36 in total

1.  A method of increasing test range and accuracy of bioindicators: Geobacillus stearothermophilus spores.

Authors:  Gunnel Lundahl
Journal:  PDA J Pharm Sci Technol       Date:  2003 Jul-Aug

2.  Evidence that ultraviolet-induced thymine dimers in DNA cause biological damage.

Authors:  R B SETLOW; J K SETLOW
Journal:  Proc Natl Acad Sci U S A       Date:  1962-07-15       Impact factor: 11.205

3.  Effectiveness of three decontamination treatments against influenza virus applied to filtering facepiece respirators.

Authors:  Michael B Lore; Brian K Heimbuch; Teanne L Brown; Joseph D Wander; Steven H Hinrichs
Journal:  Ann Occup Hyg       Date:  2011-08-22

4.  Effects of clinical isolates of Pseudomonas aeruginosa on Staphylococcus epidermidis biofilm formation.

Authors:  Maria Pihl; Luis E Chávez de Paz; Artur Schmidtchen; Gunnel Svensäter; Julia R Davies
Journal:  FEMS Immunol Med Microbiol       Date:  2010-05-29

5.  D-values of Bacillus pumilus spores on irradiated devices (inoculated product).

Authors:  H N Prince
Journal:  Appl Environ Microbiol       Date:  1978-08       Impact factor: 4.792

6.  The history of ultraviolet germicidal irradiation for air disinfection.

Authors:  Nicholas G Reed
Journal:  Public Health Rep       Date:  2010 Jan-Feb       Impact factor: 2.792

7.  Activation and inactivation of Bacillus pumilus spores by kiloelectron volt X-ray irradiation.

Authors:  Thi Mai Hoa Ha; Derrick Yong; Elizabeth Mei Yin Lee; Prathab Kumar; Yuan Kun Lee; Weibiao Zhou
Journal:  PLoS One       Date:  2017-05-11       Impact factor: 3.240

8.  Analysis of residual chemicals on filtering facepiece respirators after decontamination.

Authors:  W B Salter; K Kinney; W H Wallace; A E Lumley; B K Heimbuch; J D Wander
Journal:  J Occup Environ Hyg       Date:  2010-08       Impact factor: 2.155

9.  Pseudomonas aeruginosa, Staphylococcus aureus, and fluoroquinolone use.

Authors:  Conan MacDougall; Spencer E Harpe; J Patrick Powell; Christopher K Johnson; Michael B Edmond; Ron E Polk
Journal:  Emerg Infect Dis       Date:  2005-08       Impact factor: 6.883

10.  Decontamination of face masks with steam for mask reuse in fighting the pandemic COVID-19: Experimental supports.

Authors:  Qing-Xia Ma; Hu Shan; Chuan-Mei Zhang; Hong-Liang Zhang; Gui-Mei Li; Rui-Mei Yang; Ji-Ming Chen
Journal:  J Med Virol       Date:  2020-06-16       Impact factor: 20.693

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  2 in total

Review 1.  Disinfection and decontamination in the context of SARS-CoV-2-specific data.

Authors:  Nevio Cimolai
Journal:  J Med Virol       Date:  2022-07-18       Impact factor: 20.693

2.  Ultraviolet-C Irradiation, Heat, and Storage as Potential Methods of Inactivating SARS-CoV-2 and Bacterial Pathogens on Filtering Facepiece Respirators.

Authors:  Rhodri Harfoot; Deborah B Y Yung; William A Anderson; Cervantée E K Wild; Nicolene Coetzee; Leonor C Hernández; Blair Lawley; Daniel Pletzer; José G B Derraik; Yvonne C Anderson; Miguel E Quiñones-Mateu
Journal:  Pathogens       Date:  2022-01-10
  2 in total

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