Literature DB >> 33463048

Inhibition of ULK1 promotes the death of leukemia cell in an autophagy irrelevant manner and exerts the antileukemia effect.

Wei Yang1,2, Yunlei Li1, Shuai Liu1,3, Weimin Sun1, Hualan Huang4, Qiqing Zhang2, Jie Yan1.   

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Year:  2021        PMID： 33463048      PMCID： PMC7803353          DOI： 10.1002/ctm2.282

Source DB:  PubMed          Journal:  Clin Transl Med        ISSN： 2001-1326


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  7 in total

1.  ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.

Authors:  Terytty Yang Li; Yu Sun; Yu Liang; Qing Liu; Yuzhe Shi; Chen-Song Zhang; Cixiong Zhang; Lintao Song; Pu Zhang; Xianzhong Zhang; Xiaotong Li; Tao Chen; Hui-Ying Huang; Xiadi He; Yi Wang; Yu-Qing Wu; Shaoxuan Chen; Ming Jiang; Canhe Chen; Changchuan Xie; James Y Yang; Yan Lin; Shimin Zhao; Zhiyun Ye; Shu-Yong Lin; Daniel Tsun-Yee Chiu; Sheng-Cai Lin
Journal:  Mol Cell       Date:  2016-05-05       Impact factor: 17.970

2.  SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways.

Authors:  Fang Tang; Pengchao Hu; Zetian Yang; Chao Xue; Jun Gong; Shaoxing Sun; Liu Shi; Shimin Zhang; Zhenzhen Li; Chunxu Yang; Junhong Zhang; Conghua Xie
Journal:  Oncol Rep       Date:  2017-05-10       Impact factor: 3.906

Review 3.  Canonical and noncanonical functions of ULK/Atg1.

Authors:  Bo Wang; Mondira Kundu
Journal:  Curr Opin Cell Biol       Date:  2017-03-11       Impact factor: 8.382

Review 4.  Acute myeloid leukaemia.

Authors:  Nicholas J Short; Michael E Rytting; Jorge E Cortes
Journal:  Lancet       Date:  2018-08-02       Impact factor: 79.321

5.  Pyridoxine induces monocyte-macrophages death as specific treatment of acute myeloid leukemia.

Authors:  Wei Yang; Shuai Liu; Yunlei Li; Yujie Wang; Yao Deng; Weimin Sun; Hualan Huang; Junmou Xie; Andong He; Honglv Chen; Ailin Tao; Jie Yan
Journal:  Cancer Lett       Date:  2020-08-26       Impact factor: 8.679

6.  ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

Authors:  Ryan C Russell; Ye Tian; Haixin Yuan; Hyun Woo Park; Yu-Yun Chang; Joungmok Kim; Haerin Kim; Thomas P Neufeld; Andrew Dillin; Kun-Liang Guan
Journal:  Nat Cell Biol       Date:  2013-05-19       Impact factor: 28.824

7.  Overexpression of ULK1 Represents a Potential Diagnostic Marker for Clear Cell Renal Carcinoma and the Antitumor Effects of SBI-0206965.

Authors:  Jun Lu; Ling Zhu; Luo-Ping Zheng; Qiang Cui; He-Huan Zhu; Hu Zhao; Zhou-Ji Shen; Hui-Yue Dong; Shu-Shang Chen; Wei-Zhen Wu; Jian-Ming Tan
Journal:  EBioMedicine       Date:  2018-08-02       Impact factor: 8.143
  7 in total
  3 in total

Review 1.  Autophagy in acute myeloid leukemia: a paradoxical role in chemoresistance.

Authors:  Aafreen Khan; Vivek Kumar Singh; Deepshi Thakral; Ritu Gupta
Journal:  Clin Transl Oncol       Date:  2022-02-26       Impact factor: 3.340

Review 2.  New focuses on roles of communications between endoplasmic reticulum and mitochondria in identification of biomarkers and targets.

Authors:  Linlin Zhang; Furong Yan; Liyang Li; Huirong Fu; Dongli Song; Duojiao Wu; Xiangdong Wang
Journal:  Clin Transl Med       Date:  2021-11

Review 3.  Autophagy and beyond: Unraveling the complexity of UNC-51-like kinase 1 (ULK1) from biological functions to therapeutic implications.

Authors:  Ling Zou; Minru Liao; Yongqi Zhen; Shiou Zhu; Xiya Chen; Jin Zhang; Yue Hao; Bo Liu
Journal:  Acta Pharm Sin B       Date:  2022-06-11       Impact factor: 14.903
  3 in total

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