Literature DB >> 33462200

Soliton microcomb based spectral domain optical coherence tomography.

Paul J Marchand1,2, Johann Riemensberger3, J Connor Skehan3, Jia-Jung Ho3, Martin H P Pfeiffer3, Junqiu Liu3, Christoph Hauger4, Theo Lasser5, Tobias J Kippenberg6.   

Abstract

Spectral domain optical coherence tomography (OCT) is a widely employed, minimally invasive bio-medical imaging technique, which requires a broadband light source, typically implemented by super-luminescent diodes. Recent advances in soliton based photonic integrated frequency combs (soliton microcombs) have enabled the development of low-noise, broadband chipscale frequency comb sources, whose potential for OCT imaging has not yet been unexplored. Here, we explore the use of dissipative Kerr soliton microcombs in spectral domain OCT and show that, by using photonic chipscale Si3N4 resonators in conjunction with 1300 nm pump lasers, spectral bandwidths exceeding those of commercial OCT sources are possible. We characterized the exceptional noise properties of our source (in comparison to conventional OCT sources) and demonstrate that the soliton states in microresonators exhibit a residual intensity noise floor at high offset frequencies that is ca. 3 dB lower than a traditional OCT source at identical power, and can exhibit significantly lower noise performance for powers at the milli-Watt level. Moreover, we demonstrate that classical amplitude noise of all soliton comb teeth are correlated, i.e., common mode, in contrast to superluminescent diodes or incoherent microcomb states, which opens a new avenue to improve imaging speed and performance beyond the thermal noise limit.

Entities:  

Year:  2021        PMID: 33462200     DOI: 10.1038/s41467-020-20404-9

Source DB:  PubMed          Journal:  Nat Commun        ISSN: 2041-1723            Impact factor:   14.919


  42 in total

Review 1.  Ultrahigh-resolution optical coherence tomography.

Authors:  Wolfgang Drexler
Journal:  J Biomed Opt       Date:  2004 Jan-Feb       Impact factor: 3.170

2.  Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography.

Authors:  Johannes F de Boer; Barry Cense; B Hyle Park; Mark C Pierce; Guillermo J Tearney; Brett E Bouma
Journal:  Opt Lett       Date:  2003-11-01       Impact factor: 3.776

3.  Sensitivity advantage of swept source and Fourier domain optical coherence tomography.

Authors:  Michael Choma; Marinko Sarunic; Changhuei Yang; Joseph Izatt
Journal:  Opt Express       Date:  2003-09-08       Impact factor: 3.894

4.  Performance of fourier domain vs. time domain optical coherence tomography.

Authors:  R Leitgeb; C Hitzenberger; Adolf Fercher
Journal:  Opt Express       Date:  2003-04-21       Impact factor: 3.894

5.  Optical coherence tomography.

Authors:  D Huang; E A Swanson; C P Lin; J S Schuman; W G Stinson; W Chang; M R Hee; T Flotte; K Gregory; C A Puliafito
Journal:  Science       Date:  1991-11-22       Impact factor: 47.728

6.  Extended bandwidth wavelength swept laser source for high resolution optical frequency domain imaging.

Authors:  Sahar Hosseinzadeh Kassani; Martin Villiger; Néstor Uribe-Patarroyo; Changsu Jun; Reza Khazaeinezhad; Norman Lippok; Brett E Bouma
Journal:  Opt Express       Date:  2017-04-03       Impact factor: 3.894

7.  Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy.

Authors:  Tristan Bolmont; Arno Bouwens; Christophe Pache; Mitko Dimitrov; Corinne Berclaz; Martin Villiger; Bettina M Wegenast-Braun; Theo Lasser; Patrick C Fraering
Journal:  J Neurosci       Date:  2012-10-17       Impact factor: 6.167

8.  Swept-source optical coherence tomography powered by a 1.3-μm vertical cavity surface emitting laser enables 2.3-mm-deep brain imaging in mice in vivo.

Authors:  Woo June Choi; Ruikang K Wang
Journal:  J Biomed Opt       Date:  2015-10       Impact factor: 3.170

9.  Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging.

Authors:  Benjamin J Vakoc; Ryan M Lanning; James A Tyrrell; Timothy P Padera; Lisa A Bartlett; Triantafyllos Stylianopoulos; Lance L Munn; Guillermo J Tearney; Dai Fukumura; Rakesh K Jain; Brett E Bouma
Journal:  Nat Med       Date:  2009-09-13       Impact factor: 53.440

10.  Optical coherence microscopy for deep tissue imaging of the cerebral cortex with intrinsic contrast.

Authors:  Vivek J Srinivasan; Harsha Radhakrishnan; James Y Jiang; Scott Barry; Alex E Cable
Journal:  Opt Express       Date:  2012-01-30       Impact factor: 3.894

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  3 in total

Review 1.  Spectral Interferometry with Frequency Combs.

Authors:  Krishna Twayana; Israel Rebolledo-Salgado; Ekaterina Deriushkina; Jochen Schröder; Magnus Karlsson; Victor Torres-Company
Journal:  Micromachines (Basel)       Date:  2022-04-14       Impact factor: 3.523

2.  RF properties of circular-ranging OCT signals.

Authors:  Norman Lippok; Benjamin J Vakoc
Journal:  Opt Lett       Date:  2022-04-01       Impact factor: 3.560

Review 3.  Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography.

Authors:  Rainer Leitgeb; Fabian Placzek; Elisabet Rank; Lisa Krainz; Richard Haindl; Qian Li; Mengyang Liu; Marco Andreana; Angelika Unterhuber; Tilman Schmoll; Wolfgang Drexler
Journal:  J Biomed Opt       Date:  2021-10       Impact factor: 3.758

  3 in total

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