Literature DB >> 33461561

Antipsychotic medication adherence and preventive diabetes screening in Medicaid enrollees with serious mental illness: an analysis of real-world administrative data.

Erica L Stockbridge1, Nathaniel J Webb2, Eleena Dhakal3, Manasa Garg2,4, Abiah D Loethen5, Thaddeus L Miller2, Karabi Nandy6.   

Abstract

BACKGROUND: There is excess amenable mortality risk and evidence of healthcare quality deficits for persons with serious mental illness (SMI). We sought to identify sociodemographic and clinical characteristics associated with variations in two 2015 Healthcare Effectiveness Data and Information Set (HEDIS) measures, antipsychotic medication adherence and preventive diabetes screening, among Medicaid enrollees with serious mental illness (SMI).
METHODS: We retrospectively analyzed claims data from September 2014 to December 2015 from enrollees in a Medicaid specialty health plan in Florida. All plan enrollees had SMI; analyses included continuously enrolled adults with antipsychotic medication prescriptions and schizophrenia or bipolar disorder. Associations were identified using mixed effects logistic regression models.
RESULTS: Data for 5502 enrollees were analyzed. Substance use disorders, depression, and having both schizophrenia and bipolar disorder diagnoses were associated with both HEDIS measures but the direction of the associations differed; each was significantly associated with antipsychotic medication non-adherence (a marker of suboptimal care quality) but an increased likelihood of diabetes screening (a marker of quality care). Compared to whites, blacks and Hispanics had a significantly greater risk of medication non-adherence. Increasing age was significantly associated with increasing medication adherence, but the association between age and diabetes screening varied by sex. Other characteristics significantly associated with quality variations according to one or both measures were education (associated with antipsychotic medication adherence), urbanization (relative to urban locales, residing in suburban areas was associated with both adherence and diabetes screening), obesity (associated with both adherence and diabetes screening), language (non-English speakers had a greater likelihood of diabetes screening), and anxiety, asthma, and hypertension (each positively associated with diabetes screening).
CONCLUSIONS: The characteristics associated with variations in the quality of care provided to Medicaid enrollees with SMI as gauged by two HEDIS measures often differed, and at times associations were directionally opposite. The variations in the quality of healthcare received by persons with SMI that were identified in this study can guide quality improvement and delivery system reform efforts; however, given the sociodemographic and clinical characteristics' differing associations with different measures of care quality, multidimensional approaches are warranted.

Entities:  

Keywords:  Claims data; Complex comorbidity; Diabetes screening; Healthcare effectiveness data and information set (HEDIS); Healthcare quality; Medicaid; Medication adherence; Mental health; Mixed effects logistic regression; Serious mental illness; Social determinants of health

Mesh:

Substances:

Year:  2021        PMID: 33461561      PMCID: PMC7812734          DOI: 10.1186/s12913-020-06045-0

Source DB:  PubMed          Journal:  BMC Health Serv Res        ISSN: 1472-6963            Impact factor:   2.655


  78 in total

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2.  Medication adherence in psychosis: predictors and impact on outcome. A 2-year follow-up of first-admitted subjects.

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4.  Adherence to treatment with antipsychotic medication and health care costs among Medicaid beneficiaries with schizophrenia.

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Review 5.  Antipsychotic drugs and obesity.

Authors:  Christoph U Correll; Todd Lencz; Anil K Malhotra
Journal:  Trends Mol Med       Date:  2010-12-22       Impact factor: 11.951

6.  Compliance with refilling prescriptions for atypical antipsychotic agents and its association with the risks for hospitalization, suicide, and death in patients with schizophrenia in Quebec and Saskatchewan: a retrospective database study.

Authors:  Alexandra Ward; Khajak Ishak; Irina Proskorovsky; Jaime Caro
Journal:  Clin Ther       Date:  2006-11       Impact factor: 3.393

7.  Metabolic Testing for Adults in a State Medicaid Program Receiving Antipsychotics: Remaining Barriers to Achieving Population Health Prevention Goals.

Authors:  Elaine H Morrato; Elizabeth J Campagna; Sarah E Brewer; L Miriam Dickinson; Deborah S K Thomas; Benjamin F Miller; James Dearing; Benjamin G Druss; Richard C Lindrooth
Journal:  JAMA Psychiatry       Date:  2016-07-01       Impact factor: 21.596

8.  Factors associated with medication adherence in African American and white patients with bipolar disorder.

Authors:  David E Fleck; Paul E Keck; Kimberly B Corey; Stephen M Strakowski
Journal:  J Clin Psychiatry       Date:  2005-05       Impact factor: 4.384

9.  Predictors of metabolic monitoring among schizophrenia patients with a new episode of second-generation antipsychotic use in the Veterans Health Administration.

Authors:  Lizheng Shi; Haya Ascher-Svanum; Yi-Ju Chiang; Yingnan Zhao; Vivian Fonseca; Daniel Winstead
Journal:  BMC Psychiatry       Date:  2009-12-18       Impact factor: 3.630

10.  Language preference as a predictor of access to and use of healthcare services among Hispanics in the United States.

Authors:  William S Pearson; Indu B Ahluwalia; Earl S Ford; Ali H Mokdad
Journal:  Ethn Dis       Date:  2008       Impact factor: 1.847

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  1 in total

1.  Quality of diabetes care among patients with schizophrenia. A mixed-methods study.

Authors:  Nouf M Aloudah; Hanan Almanea; Khloud Alotaibi; Khalid A Al Rubeaan
Journal:  Explor Res Clin Soc Pharm       Date:  2021-09-17
  1 in total

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