Literature DB >> 27167755

Metabolic Testing for Adults in a State Medicaid Program Receiving Antipsychotics: Remaining Barriers to Achieving Population Health Prevention Goals.

Elaine H Morrato1, Elizabeth J Campagna2, Sarah E Brewer2, L Miriam Dickinson3, Deborah S K Thomas4, Benjamin F Miller5, James Dearing6, Benjamin G Druss7, Richard C Lindrooth8.   

Abstract

IMPORTANCE: Medicaid quality indicators track diabetes mellitus and cardiovascular disease screening in adults receiving antipsychotics and/or those with serious mental illness.
OBJECTIVE: To inform performance improvement interventions by evaluating the relative importance of patient, prescriber, and practice factors affecting metabolic testing. DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort study was conducted using Missouri Medicaid administrative claims data (January 1, 2010, to December 31, 2012) linked with prescriber market data. The analysis included 9316 adults (age, 18-64 years) who were starting antipsychotic medication. Secondary analysis included the subset of adults (n = 1813) for whom prescriber knowledge, attitudes, and behavior survey data were available. Generalized estimating equations were performed to identify factors associated with failure to receive annual testing during antipsychotic treatment (adjusted odds ratio [OR], <1 favor testing). Data analysis was performed from October 1, 2014, to February 18, 2016. EXPOSURE: Oral second-generation antipsychotics. MAIN OUTCOMES AND MEASURES: A medical claim for glucose or lipid testing occurring within 180 days before and after the antipsychotic prescription claim.
RESULTS: The 9317 patients (mean [SD] age, 37.6 [12.0] years) initiated antipsychotic medication in a variety of prescriber specialty-settings: 24.3%, community mental health center (CMHC); 27.6%, non-CMHC behavioral health; 24.3%, primary care practitioners; and 23.8%, other/unknown. Annual testing rates were 79.6% for glucose and 41.2% for lipids. Failure to test glucose and lipids was most strongly associated with patient factors and health care utilization. To illustrate by using findings from glucose modeling (reported as adjusted OR [95% CI]), lower failure to receive testing was associated with older age (40-49 vs 18-29 years; 0.64 [0.55-0.74]), diagnosis of schizophrenia or bipolar disorder (0.55 [0.44-0.67]), cardiometabolic comorbidity (dyslipidemia, 0.28 [0.22-0.37]), hypertension (0.59 [0.50-0.69]), and greater outpatient utilization (>6 encounters vs none; 0.33 [0.28-0.39]). Analysis incorporating prescriber practice information found lower failure to receive glucose testing if the patient received care at a CMHC (0.74 [0.64-0.85]) or if the initiating prescriber was a primary care practitioner (0.81 [0.66-1.00]). However, the initiating prescriber specialty-setting was not associated with lipid testing. CONCLUSIONS AND RELEVANCE: Compared with prior reports, progress has been made to improve diabetes screening, but lipid screening remains particularly underutilized. Medicaid performance improvement initiatives should target all prescriber settings and not just behavioral health.

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Year:  2016        PMID: 27167755     DOI: 10.1001/jamapsychiatry.2016.0538

Source DB:  PubMed          Journal:  JAMA Psychiatry        ISSN: 2168-622X            Impact factor:   21.596


  11 in total

1.  Metformin add-on vs. antipsychotic switch vs. continued antipsychotic treatment plus healthy lifestyle education in overweight or obese youth with severe mental illness: results from the IMPACT trial.

Authors:  Christoph U Correll; Linmarie Sikich; Gloria Reeves; Jacqueline Johnson; Courtney Keeton; Marina Spanos; Sandeep Kapoor; Kristin Bussell; Leslie Miller; Tara Chandrasekhar; Eva M Sheridan; Sara Pirmohamed; Shauna P Reinblatt; Cheryl Alderman; Abigail Scheer; Irmgard Borner; Terrence C Bethea; Sarah Edwards; Robert M Hamer; Mark A Riddle
Journal:  World Psychiatry       Date:  2020-02       Impact factor: 49.548

2.  Simulated Effects of Policies to Reduce Diabetes Risk Among Adults With Schizophrenia Receiving Antipsychotics.

Authors:  Andrew W Mulcahy; Sharon-Lise Normand; John W Newcomer; Benjamin Colaiaco; Julie M Donohue; Judith R Lave; Emmett Keeler; Mark J Sorbero; Marcela Horvitz-Lennon
Journal:  Psychiatr Serv       Date:  2017-09-01       Impact factor: 3.084

3.  Real-World Data on the Adverse Metabolic Effects of Second-Generation Antipsychotics and Their Potential Determinants in Adult Patients: A Systematic Review of Population-Based Studies.

Authors:  Miquel Bernardo; Fernando Rico-Villademoros; Clemente García-Rizo; Rosa Rojo; Ricardo Gómez-Huelgas
Journal:  Adv Ther       Date:  2021-04-07       Impact factor: 3.845

4.  Providing Health Physicals and/or Health Monitoring Services in Mental Health Clinics: Impact on Laboratory Screening and Monitoring for High Risk Populations.

Authors:  Joshua Breslau; Emily Leckman-Westin; Bing Han; Diana Guarasi; Hao Yu; Marcela Horvitz-Lennon; Riti Pritam; Molly Finnerty
Journal:  Adm Policy Ment Health       Date:  2021-03

Review 5.  Physical health policies and metabolic screening in mental health care systems of sub-Saharan African countries: a systematic review.

Authors:  James Mugisha; Marc De Hert; Brendon Stubbs; David Basangwa; Davy Vancampfort
Journal:  Int J Ment Health Syst       Date:  2017-04-19

6.  Effects of primary care clinician beliefs and perceived organizational facilitators on the delivery of preventive care to individuals with mental illnesses.

Authors:  Bobbi Jo H Yarborough; Scott P Stumbo; Nancy A Perrin; Ginger C Hanson; John Muench; Carla A Green
Journal:  BMC Fam Pract       Date:  2018-01-12       Impact factor: 2.497

7.  Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice.

Authors:  Kirsti M Jakobs; Anne Posthuma; Wim J C de Grauw; Bianca W M Schalk; Reinier P Akkermans; Peter Lucassen; Tjard Schermer; Willem J J Assendelft; Marion J C Biermans
Journal:  BMC Fam Pract       Date:  2020-07-29       Impact factor: 2.497

8.  Antipsychotic medication adherence and preventive diabetes screening in Medicaid enrollees with serious mental illness: an analysis of real-world administrative data.

Authors:  Erica L Stockbridge; Nathaniel J Webb; Eleena Dhakal; Manasa Garg; Abiah D Loethen; Thaddeus L Miller; Karabi Nandy
Journal:  BMC Health Serv Res       Date:  2021-01-18       Impact factor: 2.655

9.  Identification and management of cardiometabolic risk in subjects with schizophrenia spectrum disorders: A Delphi expert consensus study.

Authors:  Silvana Galderisi; Marc De Hert; Stefano Del Prato; Andrea Fagiolini; Philip Gorwood; Stefan Leucht; Aldo Pietro Maggioni; Armida Mucci; Celso Arango
Journal:  Eur Psychiatry       Date:  2021-01-08       Impact factor: 5.361

10.  Advancing regulatory science and assessment of FDA REMS programs: A mixed-methods evaluation examining physician survey response.

Authors:  Sarah E Brewer; Elizabeth J Campagna; Elaine H Morrato
Journal:  J Clin Transl Sci       Date:  2019-09-13
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