Literature DB >> 3346079

Protection of rabbits in an infection model of toxic shock syndrome (TSS) by a TSS toxin-1-specific monoclonal antibody.

G K Best1, D F Scott, J M Kling, M R Thompson, L E Adinolfi, P F Bonventre.   

Abstract

An anti-TSST-1-specific monoclonal antibody (MAb 8-5-7) was tested for its protective capacity in a rabbit infection model to toxic shock syndrome (TSS). The challenge strain of Staphylococcus aureus (RN4710), which contained a plasmid encoding TSS toxin-1, was introduced into previously implanted chambers. Purified monoclonal antibody (1.25 mg of immunoglobulin G) administered parenterally 1 day before and 1 day after initiation of infection provided complete protection against the TSS-like syndrome and the mortality which occurred in unprotected rabbits.

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Year:  1988        PMID： 3346079      PMCID： PMC259405          DOI： 10.1128/iai.56.4.998-999.1988

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  12 in total

1.  Staphylococcal enterotoxin B and toxic-shock syndrome toxin-1 are significantly associated with non-menstrual TSS.

Authors:  P M Schlievert
Journal:  Lancet       Date:  1986-05-17       Impact factor: 79.321

2.  Expression of the cloned toxic shock syndrome toxin 1 gene (tst) in vivo with a rabbit uterine model.

Authors:  J C de Azavedo; T J Foster; P J Hartigan; J P Arbuthnott; M O'Reilly; B N Kreiswirth; R P Novick
Journal:  Infect Immun       Date:  1985-10       Impact factor: 3.441

3.  A rabbit model of toxic shock syndrome: clinicopathological features.

Authors:  R J Arko; J K Rasheed; C V Broome; F W Chandler; A L Paris
Journal:  J Infect       Date:  1984-05       Impact factor: 6.072

4.  Characterization of Staphylococcus aureus isolates from patients with toxic shock syndrome, using polyethylene infection chambers in rabbits.

Authors:  D F Scott; J M Kling; J J Kirkland; G K Best
Journal:  Infect Immun       Date:  1983-01       Impact factor: 3.441

5.  Immunological protection of rabbits infected with Staphylococcus aureus isolates from patients with toxic shock syndrome.

Authors:  D F Scott; J M Kling; G K Best
Journal:  Infect Immun       Date:  1986-08       Impact factor: 3.441

6.  Enhanced susceptibility of male rabbits to infection with a toxic shock strain of Staphylococcus aureus.

Authors:  G K Best; D F Scott; J M Kling; W F Crowell; J J Kirkland
Journal:  Infect Immun       Date:  1984-12       Impact factor: 3.441

7.  Toxic shock syndrome caused by staphylococcal enterotoxin B. A report of 2 cases in children.

Authors:  L S Milner; J de Jager; P D Thomson; R O Doehring
Journal:  S Afr Med J       Date:  1983-05-21

8.  Production of staphylococcal enterotoxin F and pyrogenic exotoxin C by Staphylococcus aureus isolates from toxic shock syndrome-associated sources.

Authors:  P F Bonventre; L Weckbach; J Staneck; P M Schlievert; M Thompson
Journal:  Infect Immun       Date:  1983-06       Impact factor: 3.441

9.  Neutralization of toxic shock syndrome toxin-1 by monoclonal antibodies in vitro and in vivo.

Authors:  P F Bonventre; M R Thompson; L E Adinolfi; Z A Gillis; J Parsonnet
Journal:  Infect Immun       Date:  1988-01       Impact factor: 3.441

10.  A rabbit model of toxic shock syndrome that uses a constant, subcutaneous infusion of toxic shock syndrome toxin 1.

Authors:  J Parsonnet; Z A Gillis; A G Richter; G B Pier
Journal:  Infect Immun       Date:  1987-05       Impact factor: 3.441
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  6 in total

1.  Identification of functional antigenic segments of toxic shock syndrome toxin 1 by differential immunoreactivity and by differential mitogenic responses of human peripheral blood mononuclear cells, using active toxin fragments.

Authors:  C Edwin; E H Kass
Journal:  Infect Immun       Date:  1989-07       Impact factor: 3.441

2.  Oligonucleotide probes for detection and differentiation of Staphylococcus aureus strains containing genes for enterotoxins A, B, and C and toxic shock syndrome toxin 1.

Authors:  R J Neill; G R Fanning; F Delahoz; R Wolff; P Gemski
Journal:  J Clin Microbiol       Date:  1990-07       Impact factor: 5.948

3.  Mutants of staphylococcal toxic shock syndrome toxin 1: mitogenicity and recognition by a neutralizing monoclonal antibody.

Authors:  L Blanco; E M Choi; K Connolly; M R Thompson; P F Bonventre
Journal:  Infect Immun       Date:  1990-09       Impact factor: 3.441

4.  The effect of vaginal microbial communities on colonization by Staphylococcus aureus with the gene for toxic shock syndrome toxin 1 (TSST-1): a case-control study.

Authors:  Jacob D Pierson; Melanie A Hansmann; Catherine C Davis; Larry J Forney
Journal:  Pathog Dis       Date:  2018-06-01       Impact factor: 3.166

5.  Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome.

Authors:  P F Bonventre; H Heeg; C Cullen; C J Lian
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441

6.  Dye labelled monoclonal antibody assay for detection of Toxic Shock Syndrome Toxin -1 from Staphylococcus aureus.

Authors:  Khojasteh V Javid; Ha Foster
Journal:  Iran J Microbiol       Date:  2011-12
  6 in total

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