Literature DB >> 33458344

Assessment of manual adjustment performed in clinical practice following deep learning contouring for head and neck organs at risk in radiotherapy.

Charlotte L Brouwer1, Djamal Boukerroui2, Jorge Oliveira2, Padraig Looney2, Roel J H M Steenbakkers1, Johannes A Langendijk1, Stefan Both1, Mark J Gooding2.   

Abstract

BACKGROUND AND
PURPOSE: Auto-contouring performance has been widely studied in development and commissioning studies in radiotherapy, and its impact on clinical workflow assessed in that context. This study aimed to evaluate the manual adjustment of auto-contouring in routine clinical practice and to identify improvements regarding the auto-contouring model and clinical user interaction, to improve the efficiency of auto-contouring.
MATERIALS AND METHODS: A total of 103 clinical head and neck cancer cases, contoured using a commercial deep-learning contouring system and subsequently checked and edited for clinical use were retrospectively taken from clinical data over a twelve-month period (April 2019-April 2020). The amount of adjustment performed was calculated, and all cases were registered to a common reference frame for assessment purposes. The median, 10th and 90th percentile of adjustment were calculated and displayed using 3D renderings of structures to visually assess systematic and random adjustment. Results were also compared to inter-observer variation reported previously. Assessment was performed for both the whole structures and for regional sub-structures, and according to the radiation therapy technologist (RTT) who edited the contour.
RESULTS: The median amount of adjustment was low for all structures (<2 mm), although large local adjustment was observed for some structures. The median was systematically greater or equal to zero, indicating that the auto-contouring tends to under-segment the desired contour.
CONCLUSION: Auto-contouring performance assessment in routine clinical practice has identified systematic improvements required technically, but also highlighted the need for continued RTT training to ensure adherence to guidelines.
© 2020 The Authors.

Entities:  

Keywords:  Auto-contouring; Automatic segmentation; Contour adjustment; Deep learning; Head and neck organs at risk; Radiotherapy

Year:  2020        PMID: 33458344      PMCID: PMC7807591          DOI: 10.1016/j.phro.2020.10.001

Source DB:  PubMed          Journal:  Phys Imaging Radiat Oncol        ISSN: 2405-6316


  19 in total

1.  CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.

Authors:  Charlotte L Brouwer; Roel J H M Steenbakkers; Jean Bourhis; Wilfried Budach; Cai Grau; Vincent Grégoire; Marcel van Herk; Anne Lee; Philippe Maingon; Chris Nutting; Brian O'Sullivan; Sandro V Porceddu; David I Rosenthal; Nanna M Sijtsema; Johannes A Langendijk
Journal:  Radiother Oncol       Date:  2015-08-13       Impact factor: 6.280

Review 2.  Statistical shape models for 3D medical image segmentation: a review.

Authors:  Tobias Heimann; Hans-Peter Meinzer
Journal:  Med Image Anal       Date:  2009-05-27       Impact factor: 8.545

3.  Recommendations on how to establish evidence from auto-segmentation software in radiotherapy.

Authors:  Vincenzo Valentini; Luca Boldrini; Andrea Damiani; Ludvig P Muren
Journal:  Radiother Oncol       Date:  2014-10-11       Impact factor: 6.280

Review 4.  Advances in Auto-Segmentation.

Authors:  Carlos E Cardenas; Jinzhong Yang; Brian M Anderson; Laurence E Court; Kristy B Brock
Journal:  Semin Radiat Oncol       Date:  2019-07       Impact factor: 5.934

5.  Evaluation of segmentation methods on head and neck CT: Auto-segmentation challenge 2015.

Authors:  Patrik F Raudaschl; Paolo Zaffino; Gregory C Sharp; Maria Francesca Spadea; Antong Chen; Benoit M Dawant; Thomas Albrecht; Tobias Gass; Christoph Langguth; Marcel Lüthi; Florian Jung; Oliver Knapp; Stefan Wesarg; Richard Mannion-Haworth; Mike Bowes; Annaliese Ashman; Gwenael Guillard; Alan Brett; Graham Vincent; Mauricio Orbes-Arteaga; David Cárdenas-Peña; German Castellanos-Dominguez; Nava Aghdasi; Yangming Li; Angelique Berens; Kris Moe; Blake Hannaford; Rainer Schubert; Karl D Fritscher
Journal:  Med Phys       Date:  2017-04-21       Impact factor: 4.071

Review 6.  Vision 20/20: perspectives on automated image segmentation for radiotherapy.

Authors:  Gregory Sharp; Karl D Fritscher; Vladimir Pekar; Marta Peroni; Nadya Shusharina; Harini Veeraraghavan; Jinzhong Yang
Journal:  Med Phys       Date:  2014-05       Impact factor: 4.071

7.  Clinical evaluation of atlas and deep learning based automatic contouring for lung cancer.

Authors:  Tim Lustberg; Johan van Soest; Mark Gooding; Devis Peressutti; Paul Aljabar; Judith van der Stoep; Wouter van Elmpt; Andre Dekker
Journal:  Radiother Oncol       Date:  2017-12-05       Impact factor: 6.280

8.  Segmentation of organs-at-risks in head and neck CT images using convolutional neural networks.

Authors:  Bulat Ibragimov; Lei Xing
Journal:  Med Phys       Date:  2017-02       Impact factor: 4.071

9.  Improving automatic delineation for head and neck organs at risk by Deep Learning Contouring.

Authors:  Lisanne V van Dijk; Lisa Van den Bosch; Paul Aljabar; Devis Peressutti; Stefan Both; Roel J H M Steenbakkers; Johannes A Langendijk; Mark J Gooding; Charlotte L Brouwer
Journal:  Radiother Oncol       Date:  2019-10-22       Impact factor: 6.280

10.  Automated Quality Assurance of OAR Contouring for Lung Cancer Based on Segmentation With Deep Active Learning.

Authors:  Kuo Men; Huaizhi Geng; Tithi Biswas; Zhongxing Liao; Ying Xiao
Journal:  Front Oncol       Date:  2020-07-03       Impact factor: 6.244

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  5 in total

1.  Real-world analysis of manual editing of deep learning contouring in the thorax region.

Authors:  Femke Vaassen; Djamal Boukerroui; Padraig Looney; Richard Canters; Karolien Verhoeven; Stephanie Peeters; Indra Lubken; Jolein Mannens; Mark J Gooding; Wouter van Elmpt
Journal:  Phys Imaging Radiat Oncol       Date:  2022-05-14

Review 2.  Barriers and facilitators to clinical implementation of radiotherapy treatment planning automation: A survey study of medical dosimetrists.

Authors:  Rachel Petragallo; Naomi Bardach; Ezequiel Ramirez; James M Lamb
Journal:  J Appl Clin Med Phys       Date:  2022-03-03       Impact factor: 2.243

3.  Optimising a 3D convolutional neural network for head and neck computed tomography segmentation with limited training data.

Authors:  Edward G A Henderson; Eliana M Vasquez Osorio; Marcel van Herk; Andrew F Green
Journal:  Phys Imaging Radiat Oncol       Date:  2022-04-28

4.  Validation of an established deep learning auto-segmentation tool for cardiac substructures in 4D radiotherapy planning scans.

Authors:  Gerard M Walls; Valentina Giacometti; Aditya Apte; Maria Thor; Conor McCann; Gerard G Hanna; John O'Connor; Joseph O Deasy; Alan R Hounsell; Karl T Butterworth; Aidan J Cole; Suneil Jain; Conor K McGarry
Journal:  Phys Imaging Radiat Oncol       Date:  2022-07-26

5.  Challenges and chances for deep-learning based target and organ at risk segmentation in radiotherapy of head and neck cancer.

Authors:  Jasper Nijkamp
Journal:  Phys Imaging Radiat Oncol       Date:  2022-08-11
  5 in total

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