Literature DB >> 33457691

Thrombi Within the Urinary Tract May Serve as a Nidus for Rapid Stone Recurrence: A Report of Two Cases.

Ashley V Alford1, Matthew Mocol1, Michael S Borofsky1.   

Abstract

Background: Nephrolithiasis is increasingly becoming one of the most prevalent and costly urologic conditions in the United States. The most common type of kidney stone in humans is calcium oxalate, accounting for 75% of idiopathic stones in first-time stone formers. Stone formation is typically a gradual process; however, certain factors can accelerate stone development and recurrence. Case Presentation: We present two cases of adult white men who were found to have rapidly recurrent symptomatic kidney stones that were ultimately determined to be comprised of an outer mineral shell with an inner core of blood clot. Both patients had a history of nephrolithiasis and recent hematuria. Urine supersaturation values at time of presentation supported formation of kidney stones.
Conclusion: Thrombi within the urinary tract can serve as a nidus for formation of multiple types of kidney stones, including calcium oxalate and uric acid stones. Stones arising from such a nidus may exhibit unusually rapid growth. Copyright 2020, Mary Ann Liebert, Inc., publishers.

Entities:  

Keywords:  recurrent stone disease; urinary thrombi; urolithiasis

Year:  2020        PMID: 33457691      PMCID: PMC7803211          DOI: 10.1089/cren.2020.0175

Source DB:  PubMed          Journal:  J Endourol Case Rep        ISSN: 2379-9889


  4 in total

1.  Evaluation of trends in urolith composition in cats: 5,230 cases (1985-2004).

Authors:  Allison B Cannon; Jodi L Westropp; Annette L Ruby; Philip H Kass
Journal:  J Am Vet Med Assoc       Date:  2007-08-15       Impact factor: 1.936

2.  Dried solidified blood calculi in the urinary tract of cats.

Authors:  Jodi L Westropp; Annette L Ruby; Nathan L Bailiff; Andrew E Kyles; Gerald V Ling
Journal:  J Vet Intern Med       Date:  2006 Jul-Aug       Impact factor: 3.333

3.  Prevalence of kidney stones in the United States.

Authors:  Charles D Scales; Alexandria C Smith; Janet M Hanley; Christopher S Saigal
Journal:  Eur Urol       Date:  2012-03-31       Impact factor: 20.096

4.  Further evidence linking urolithiasis and blood coagulation: urinary prothrombin fragment 1 is present in stone matrix.

Authors:  A M Stapleton; C J Dawson; P K Grover; A Hohmann; R Comacchio; V Boswarva; Y Tang; R L Ryall
Journal:  Kidney Int       Date:  1996-03       Impact factor: 10.612

  4 in total

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