Sulaiman C T1, Deepak M1, Ramesh P R2, Mahesh K2, Anandan E M3, Indira Balachandran1. 1. Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, Malappuram, Kerala 676503 India. 2. Clinical Research Department, Arya Vaidya Sala, Kottakkal, Kerala India. 3. Product Development Department, Arya Vaidya Sala, Kottakkal, Kerala India.
Abstract
BACKGROUND: The novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the global health concern since December 2019. It has become a big challenge for the researchers to find a solution for this newly evolved pandemic. In Ayurveda point of view, COVID-19 is a Janapadodhwamsa vikara (epidemic disease), a situation where the environment-air, water, land, and seasons-is vitiated, causing a simultaneous manifestation of a disease among large populations. The aim of this study is to identify the active compounds of selected Ayurveda medicines recommended for COVID-19. RESULTS: The selected preparations are traditionally recommended for the management of various kinds of fever including the infectious ones and to enhance the immunity. HPTLC analysis of the same showed presence of many active molecules like umbelliferone, scopoletin, caffeic acid, ferulic acid, gallic acid, piperine, curcumin, berberine, and palmatine. CONCLUSION: The study provided valuable scientific data regarding the active ingredients of the selected medicines with proven therapeutic potentials like anti-viral, immunomodulatory, and anti-inflammatory activities.
BACKGROUND: The novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the global health concern since December 2019. It has become a big challenge for the researchers to find a solution for this newly evolved pandemic. In Ayurveda point of view, COVID-19 is a Janapadodhwamsa vikara (epidemic disease), a situation where the environment-air, water, land, and seasons-is vitiated, causing a simultaneous manifestation of a disease among large populations. The aim of this study is to identify the active compounds of selected Ayurveda medicines recommended for COVID-19. RESULTS: The selected preparations are traditionally recommended for the management of various kinds of fever including the infectious ones and to enhance the immunity. HPTLC analysis of the same showed presence of many active molecules like umbelliferone, scopoletin, caffeic acid, ferulic acid, gallic acid, piperine, curcumin, berberine, and palmatine. CONCLUSION: The study provided valuable scientific data regarding the active ingredients of the selected medicines with proven therapeutic potentials like anti-viral, immunomodulatory, and anti-inflammatory activities.
Authors: Che C Colpitts; Luis M Schang; Heni Rachmawati; Anne Frentzen; Stephanie Pfaender; Patrick Behrendt; Richard J P Brown; Dorothea Bankwitz; Joerg Steinmann; Michael Ott; Philip Meuleman; Charles M Rice; Alexander Ploss; Thomas Pietschmann; Eike Steinmann Journal: Gut Date: 2014-07 Impact factor: 23.059
Authors: Daniel P Bezerra; Fernanda O de Castro; Ana Paula N N Alves; Cláudia Pessoa; Manoel Odorico de Moraes; Edilberto R Silveira; Mary Anne S Lima; Francisca Juliana M Elmiro; Nylane M N de Alencar; Rodney O Mesquita; Michael W Lima; Letícia V Costa-Lotufo Journal: J Appl Toxicol Date: 2008-03 Impact factor: 3.446