Literature DB >> 17239594

Antiviral activity of berberine and related compounds against human cytomegalovirus.

Kyoko Hayashi1, Kazuki Minoda, Yasuo Nagaoka, Toshimitsu Hayashi, Shinichi Uesato.   

Abstract

Berberine chloride (1) and the structurally related compounds were assessed for the anti-human cytomegalovirus (HCMV) activity using the plaque assay. The anti-HCMV activity (IC(50) 0.68 microM) of 1 was equivalent to that (IC(50) 0.91 microM) of ganciclovir (GCV). The mechanism of action by which 1 inhibits the replication of HCMV is presumed to be different from that of GCV; 1 would interfere with intracellular events after virus penetration into the host cells and before viral DNA synthesis.

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Year:  2007        PMID： 17239594     DOI： 10.1016/j.bmcl.2006.12.085

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  31 in total

1.  Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures.

Authors:  Clement Lin; Guanhui Wu; Kaibo Wang; Buket Onel; Saburo Sakai; Yong Shao; Danzhou Yang
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-18       Impact factor: 15.336

2.  Anti-viral effects of urosolic acid on guinea pig cytomegalovirus in vitro.

Authors:  Jingjing Zhao; Juanjuan Chen; Tao Liu; Jianguo Fang; Jin Wan; Jianhua Zhao; Wei Li; Jing Liu; Xianzhe Zhao; Suhua Chen
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2012-12-28

Review 3.  Biologically active isoquinoline alkaloids covering 2014-2018.

Authors:  Xiao-Fei Shang; Cheng-Jie Yang; Susan L Morris-Natschke; Jun-Cai Li; Xiao-Dan Yin; Ying-Qian Liu; Xiao Guo; Jing-Wen Peng; Masuo Goto; Ji-Yu Zhang; Kuo-Hsiung Lee
Journal:  Med Res Rev       Date:  2020-07-29       Impact factor: 12.944

4.  Physicochemical characterization of berberine chloride: a perspective in the development of a solution dosage form for oral delivery.

Authors:  Sunil Kumar Battu; Michael A Repka; Sindhuri Maddineni; Amar G Chittiboyina; Mitchell A Avery; Soumyajit Majumdar
Journal:  AAPS PharmSciTech       Date:  2010-09-15       Impact factor: 3.246

5.  Antibacterial activity and mechanism of berberine against Streptococcus agalactiae.

Authors:  Lianci Peng; Shuai Kang; Zhongqiong Yin; Renyong Jia; Xu Song; Li Li; Zhengwen Li; Yuanfeng Zou; Xiaoxia Liang; Lixia Li; Changliang He; Gang Ye; Lizi Yin; Fei Shi; Cheng Lv; Bo Jing
Journal:  Int J Clin Exp Pathol       Date:  2015-05-01

6.  Antibacterial activity of a berberine nanoformulation.

Authors:  Hue Thi Nguyen; Tuyet Nhung Pham; Anh-Tuan Le; Nguyen Thanh Thuy; Tran Quang Huy; Thuy Thi Thu Nguyen
Journal:  Beilstein J Nanotechnol       Date:  2022-07-11       Impact factor: 3.272

7.  Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.

Authors:  Motilal Maiti; Gopinatha Suresh Kumar
Journal:  J Nucleic Acids       Date:  2009-12-15

8.  Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo.

Authors:  Yuchen Cai; Qing Xia; Rongzhen Luo; Peiyu Huang; Yueli Sun; Yanxia Shi; Wenqi Jiang
Journal:  J Nat Med       Date:  2013-04-21       Impact factor: 2.343

9.  Downregulation of cellular c-Jun N-terminal protein kinase and NF-κB activation by berberine may result in inhibition of herpes simplex virus replication.

Authors:  Siwei Song; Min Qiu; Ying Chu; Deyan Chen; Xiaohui Wang; Airong Su; Zhiwei Wu
Journal:  Antimicrob Agents Chemother       Date:  2014-06-09       Impact factor: 5.191

Review 10.  Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers.

Authors:  Miroslava Šudomová; Kateřina Berchová-Bímová; Stefania Marzocco; Alena Liskova; Peter Kubatka; Sherif T S Hassan
Journal:  Viruses       Date:  2021-05-28       Impact factor: 5.048
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