Literature DB >> 33456624

Perspectives on and preferences for on-demand and long-acting PrEP among sexual and gender minority adolescents assigned male at birth.

Kathryn Macapagal1,2, Mara Nery-Hurwit1,2, Margaret Matson1,2, Shariell Crosby1,2, George J Greene1.   

Abstract

INTRODUCTION: Sexual and gender minority (SGM) adolescents assigned male at birth who have sex with male partners are at increased risk for HIV. Daily oral pre-exposure prophylaxis (PrEP) is available for minor adolescents in the United States, who may have difficulty with adherence. Adolescents' perspectives toward emerging PrEP delivery methods that would not require daily pill-taking have not been well-explored.
METHODS: We conducted online surveys and focus groups in November 2018-February 2019 with 59 SGM adolescents assigned male at birth who reported sex with or attraction to male partners. Questions assessed their perspectives on and preferences for biomedical (on-demand, injection, implant) and non-biomedical HIV prevention options (condoms). Data were analyzed thematically.
RESULTS: Of all prevention options, the implant and condoms were rated highest, and participants preferred the implant over other biomedical options. Convenience, duration, and ease of access played important roles in adolescents' preferences. Parents were viewed as a barrier to taking PrEP regardless of delivery method due to their role in adolescents' ability to access healthcare.
CONCLUSIONS: SGM adolescents are interested in long-acting PrEP, yet also perceive substantial obstacles to using biomedical prevention that reflect adolescents' developmental contexts. POLICY IMPLICATIONS: State laws expanding adolescents' access to HIV preventive services, sex education inclusive of PrEP information, and parent- and provider-initiated PrEP conversations can reduce barriers regardless of PrEP delivery method. Research to accelerate the availability of long-acting implants for adolescents is needed.

Entities:  

Keywords:  HIV; adolescent behavior; pre-exposure prophylaxis; sexual and gender minorities; sexual behavior

Year:  2020        PMID: 33456624      PMCID: PMC7810244          DOI: 10.1007/s13178-020-00441-1

Source DB:  PubMed          Journal:  Sex Res Social Policy        ISSN: 1553-6610


  36 in total

1.  Development of a measure of barriers to HIV testing among individuals at high risk.

Authors:  Germine H Awad; Lynda M Sagrestano; Mark J Kittleson; Paul D Sarvela
Journal:  AIDS Educ Prev       Date:  2004-04

2.  Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.

Authors:  Robert M Grant; Javier R Lama; Peter L Anderson; Vanessa McMahan; Albert Y Liu; Lorena Vargas; Pedro Goicochea; Martín Casapía; Juan Vicente Guanira-Carranza; Maria E Ramirez-Cardich; Orlando Montoya-Herrera; Telmo Fernández; Valdilea G Veloso; Susan P Buchbinder; Suwat Chariyalertsak; Mauro Schechter; Linda-Gail Bekker; Kenneth H Mayer; Esper Georges Kallás; K Rivet Amico; Kathleen Mulligan; Lane R Bushman; Robert J Hance; Carmela Ganoza; Patricia Defechereux; Brian Postle; Furong Wang; J Jeff McConnell; Jia-Hua Zheng; Jeanny Lee; James F Rooney; Howard S Jaffe; Ana I Martinez; David N Burns; David V Glidden
Journal:  N Engl J Med       Date:  2010-11-23       Impact factor: 91.245

3.  PrEP Awareness, Uptake, Barriers, and Correlates Among Adolescents Assigned Male at Birth Who Have Sex with Males in the U.S.

Authors:  Kathryn Macapagal; Ashley Kraus; Aaron K Korpak; Kyle Jozsa; David A Moskowitz
Journal:  Arch Sex Behav       Date:  2019-10-10

4.  Facilitators and Barriers to Participation in PrEP HIV Prevention Trials Involving Transgender Male and Female Adolescents and Emerging Adults.

Authors:  Celia B Fisher; Adam L Fried; Margaret Desmond; Kathryn Macapagal; Brian Mustanski
Journal:  AIDS Educ Prev       Date:  2017-06

5.  Diagnosed HIV Infection in Transgender Adults and Adolescents: Results from the National HIV Surveillance System, 2009-2014.

Authors:  Hollie Clark; Aruna Surendera Babu; Ellen Weiss Wiewel; Jenevieve Opoku; Nicole Crepaz
Journal:  AIDS Behav       Date:  2017-09

6.  Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study.

Authors:  Jean-Michel Molina; Isabelle Charreau; Bruno Spire; Laurent Cotte; Julie Chas; Catherine Capitant; Cecile Tremblay; Daniela Rojas-Castro; Eric Cua; Armelle Pasquet; Camille Bernaud; Claire Pintado; Constance Delaugerre; Luis Sagaon-Teyssier; Soizic Le Mestre; Christian Chidiac; Gilles Pialoux; Diane Ponscarme; Julien Fonsart; David Thompson; Mark A Wainberg; Veronique Doré; Laurence Meyer
Journal:  Lancet HIV       Date:  2017-07-23       Impact factor: 12.767

7.  Self-Consent for HIV Prevention Research Involving Sexual and Gender Minority Youth: Reducing Barriers Through Evidence-Based Ethics.

Authors:  Celia B Fisher; Miriam R Arbeit; Melissa S Dumont; Kathryn Macapagal; Brian Mustanski
Journal:  J Empir Res Hum Res Ethics       Date:  2016-03-07       Impact factor: 1.742

8.  Transgender Women's Concerns and Preferences on Potential Future Long-Acting Biomedical HIV Prevention Strategies: The Case of Injections and Implanted Medication Delivery Devices (IMDDs).

Authors:  Christine Tagliaferri Rael; Michelle Martinez; Rebecca Giguere; Walter Bockting; Caitlin MacCrate; Will Mellman; Pablo Valente; George J Greene; Susan G Sherman; Katherine H A Footer; Richard T D'Aquila; Alex Carballo-Diéguez; Thomas J Hope
Journal:  AIDS Behav       Date:  2020-05

9.  Cost effectiveness of 'on demand' HIV pre-exposure prophylaxis for non-injection drug-using men who have sex with men in Canada.

Authors:  Estelle Ouellet; Madeleine Durand; Jason R Guertin; Jacques LeLorier; Cécile L Tremblay
Journal:  Can J Infect Dis Med Microbiol       Date:  2015 Jan-Feb       Impact factor: 2.471

10.  "Free Testing and PrEP without Outing Myself to Parents:" Motivation to participate in oral and injectable PrEP clinical trials among adolescent men who have sex with men.

Authors:  Celia B Fisher; Adam L Fried; Leah Ibrahim Puri; Kathryn Macapagal; Brian Mustanski
Journal:  PLoS One       Date:  2018-07-25       Impact factor: 3.240

View more
  4 in total

1.  "It's Very Inconvenient for Me": A Mixed-Method Study Assessing Barriers and Facilitators of Adolescent Sexual Minority Males Attending PrEP Follow-Up Appointments.

Authors:  Christopher Owens; Kevin Moran; Melissa Mongrella; David A Moskowitz; Brian Mustanski; Kathryn Macapagal
Journal:  AIDS Behav       Date:  2021-06-03

2.  Awareness and Knowledge of Pre-exposure Prophylaxis Among Sexual and Gender Minority Adolescents Assigned Male at Birth in the United States.

Authors:  Margaret Matson; Mara Nery-Hurwit; Shariell Crosby; George J Greene; Kathryn Macapagal
Journal:  Arch Sex Behav       Date:  2021-05-12

3.  Zero knowledge and high interest in the use of long-acting injectable pre-exposure prophylaxis (PrEP) among adolescent men who have sex with men and transgender women in two capital cities in Brazil.

Authors:  Leo Pedrana; Laio Magno; Eliana Miura Zucchi; Luís Augusto Vasconcelos da Silva; Dulce Ferraz; Alexandre Grangeiro; Marcelo Castellanos; Sandra Assis Brasil; Inês Dourado
Journal:  BMC Public Health       Date:  2022-09-12       Impact factor: 4.135

4.  A multi-country cross-sectional study to assess predictors of daily versus on-demand oral pre-exposure prophylaxis in youth from South Africa, Uganda and Zimbabwe.

Authors:  Janan Janine Dietrich; Nadia Ahmed; Emily L Webb; Gugulethu Tshabalala; Stefanie Hornschuh; Mamakiri Mulaudzi; Millicent Atujuna; Lynda Stranix-Chibanda; Teacler Nematadzira; Andrew Sentoogo Ssemata; Richard Muhumuza; Janet Seeley; Linda-Gail Bekker; Helen A Weiss; Neil Martinson; Julie Fox
Journal:  J Int AIDS Soc       Date:  2022-08       Impact factor: 6.707

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.