Literature DB >> 33452982

Biodistribution of 68Ga-NODA-Aminoglucose in Intact and Tumor-Bearing Mice.

V K Tishchenko1,2, V M Petriev3,4, A A Mikhailovskaya1, P V Shegai1, S A Ivanov1, A D Kaprin1.   

Abstract

We studied the biodistribution of 68Ga-NODA-aminoglucose (68Ga-NODA-AG) in normal mice and mice with experimental model of colon adenocarcinoma tumor. It was shown that 68Ga-NODA-aminoglucose was retained in the tumor for 3 h after injection and demonstrated high level of accumulation in the tumor. Rapid clearance of radioactivity from other organs was observed. The results suggest that 68Ga-NODA-aminoglucose is a promising agent for tumor visualization by positron emission tomography.

Entities:  

Keywords:  aminoglucose; colon adenocarcinoma; gallium-68; positron emission tomography

Year:  2021        PMID： 33452982     DOI： 10.1007/s10517-021-05064-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  2 in total

1.  Synthesis and evaluation of (68)Ga-labeled DOTA-2-deoxy-D-glucosamine as a potential radiotracer in μPET imaging.

Authors:  Zhi Yang; Chiyi Xiong; Rui Zhang; Hua Zhu; Chun Li
Journal:  Am J Nucl Med Mol Imaging       Date:  2012-10-15

2.  Experimental Study of the Biodistribution of New Bone-Seeking Compounds Based on Phosphonic Acids and Gallium-68.

Authors:  V K Tishchenko; V M Petriev; A A Mikhailovskaya; E D Stepchenkova; V Yu Timoshenko; A A Postnov; I N Zavestovskaya
Journal:  Bull Exp Biol Med       Date:  2020-04-25       Impact factor: 0.804
  2 in total

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