Literature DB >> 33451307

ACTION trial: a prospective study on diagnostic Accuracy of 4D CT for diagnosing Instable ScaphOlunate DissociatioN.

Leonie Goelz1,2, Simon Kim3, Claas Güthoff4, Frank Eichenauer5, Andreas Eisenschenk3,5, Sven Mutze6,7, Ariane Asmus5.   

Abstract

BACKGROUND: Early detection of scapholunate ligament (SLL) tears is essential after minor and major trauma to the wrist. The differentiation between stable and instable injuries determines therapeutic measures which aim to prevent osteoarthritis. Arthroscopy has since been the diagnostic gold standard in suspected SLL tears because non-invasive methods have failed to exclude instable injuries reliably. This prospective study aims to determine the diagnostic accuracy of dynamic, 4D computed tomography (CT) of the wrist for diagnosing instable SLL tears.
METHODS: Single center, prospective trial including 40 patients with suspected SLL tears scheduled for arthroscopy. Diagnostic accuracy of 4D CT will be tested against the reference standard arthroscopy. Radiologists will be blinded to the results of arthroscopy and hand surgeons to radiological reports. A historical cohort of 80 patients which was diagnosed using cineradiography before implementation of 4D CT at the study site will serve as a comparative group. DISCUSSION: Static imaging lacks the ability to detect instable SLL tears after wrist trauma. Dynamic methods such as cineradiography and dynamic magnetic resonance imaging (MRI) are complex and require specific technical infrastructure in specialized centers. Modern super-fast dual source CT scanners are gaining popularity and are being installed gradually in hospitals and ambulances. These scanners enable dynamic imaging in a quick and simple manner. Establishment of dynamic 4D CT of the wrist in patients with suspected SLL tears in in- and outpatient settings could improve early detection rates. Reliable identification of instable injuries through 4D CT scans might reduce the number of unnecessary diagnostic arthroscopies in the future. TRIAL REGISTRATION: This study was registered prospectively at the German Clinical Trials Register (DRKS) DRKS00021110 . Universal Trial Number (WHO-UTN): U1111-1249-7884.

Entities:  

Keywords:  4D CT; Arthroscopy; Cineradiography; Diagnostic accuracy; Dynamic; Scapholunate ligament; Wrist

Mesh:

Year:  2021        PMID: 33451307      PMCID: PMC7811226          DOI: 10.1186/s12891-021-03946-x

Source DB:  PubMed          Journal:  BMC Musculoskelet Disord        ISSN: 1471-2474            Impact factor:   2.362


  22 in total

1.  Measurements of carpal bone angles on lateral wrist radiographs.

Authors:  C F Larsen; F K Mathiesen; S Lindequist
Journal:  J Hand Surg Am       Date:  1991-09       Impact factor: 2.230

2.  Intrinsic ligament and triangular fibrocartilage complex tears of the wrist: comparison of MDCT arthrography, conventional 3-T MRI, and MR arthrography.

Authors:  Ryan K L Lee; Alex W H Ng; Cina S L Tong; James F Griffith; W L Tse; C Wong; P C Ho
Journal:  Skeletal Radiol       Date:  2013-06-28       Impact factor: 2.199

3.  Assessment of scapholunate instability with dynamic computed tomography.

Authors:  Lionel Athlani; Kamel Rouizi; Jonathan Granero; Gabriela Hossu; Alain Blum; Gilles Dautel; Pedro Augusto Gondim Teixeira
Journal:  J Hand Surg Eur Vol       Date:  2019-12-16

4.  Cine MRI: a new approach to the diagnosis of scapholunate dissociation.

Authors:  I Langner; S Fischer; A Eisenschenk; S Langner
Journal:  Skeletal Radiol       Date:  2015-03-12       Impact factor: 2.199

5.  Radiation exposure during endovascular aneurysm repair.

Authors:  R A Weerakkody; S R Walsh; C Cousins; K E Goldstone; T Y Tang; M E Gaunt
Journal:  Br J Surg       Date:  2008-06       Impact factor: 6.939

6.  Comparison of conventional MRI and MR arthrography in the evaluation wrist ligament tears: A preliminary experience.

Authors:  Shivani Pahwa; Deep N Srivastava; Raju Sharma; Shivanand Gamanagatti; Prakash P Kotwal; Vijay Sharma
Journal:  Indian J Radiol Imaging       Date:  2014-07

Review 7.  Wrist cineradiography: a protocol for diagnosing carpal instability.

Authors:  G S I Sulkers; S D Strackee; N W L Schep; M Maas
Journal:  J Hand Surg Eur Vol       Date:  2017-03-01

Review 8.  Optimal management of scapholunate ligament injuries.

Authors:  Geoffrey Konopka; Harvey Chim
Journal:  Orthop Res Rev       Date:  2018-08-06

9.  Understanding and using sensitivity, specificity and predictive values.

Authors:  Rajul Parikh; Annie Mathai; Shefali Parikh; G Chandra Sekhar; Ravi Thomas
Journal:  Indian J Ophthalmol       Date:  2008 Jan-Feb       Impact factor: 1.848

10.  Four-dimensional real-time cine images of wrist joint kinematics using dual source CT with minimal time increment scanning.

Authors:  Yoon Seong Choi; Young Han Lee; Sungjun Kim; Hee Woo Cho; Ho-Taek Song; Jin-Suck Suh
Journal:  Yonsei Med J       Date:  2013-07       Impact factor: 2.759

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