BACKGROUND: Healthcare-associated infections (HAIs) pose a serious risk to patient safety and quality of care. The Canadian Nosocomial Infection Surveillance Program (CNISP) conducts national surveillance of HAIs at sentinel acute-care hospitals across Canada. This report provides an overview of 10 years of Canadian data on the epidemiology of select device-associated HAIs. METHODS: Over 40 hospitals submitted data between 2009 and 2018 for hip and knee surgical site infections (SSIs), cerebrospinal fluid shunt SSIs, paediatric cardiac SSIs and/or central line-associated bloodstream infections (CLABSIs). Counts, rates, patient and hospital characteristics, as well as pathogen distributions and antimicrobial susceptibilities are presented. RESULTS: A total of 4,300 device-associated infections were reported. Central line-associated bloodstream infections were the most common device-associated HAI reported (n=2,973, 69%) and hip and knee arthroplasty infections were the most common SSIs reported (66% of SSIs). Our findings show decreasing CLABSI rates in neonatal intensive care units (4.2 to 1.9 per 1,000 line-days, p<0.0001) and decreasing knee SSI rates (0.69 to 0.30 infections per 100 surgeries, p=0.007). Rates of device-associated HAIs have remained relatively consistent over the 10-year surveillance period. Overall, 4,599 pathogens were identified from device-associated HAI; 70% of these were related to CLABSIs. Coagulase-negative staphylococci (29%) and Staphylococcus aureus (14%) were the most frequently reported pathogens. Gram-positive pathogens represented 68% of identified pathogens, gram-negative pathogens represented 22% and fungi represented 9%. CONCLUSION: Understanding the national burden of device-associated HAIs is essential for developing and maintaining benchmark rates for informing infection and prevention control and antimicrobial stewardship policies and programs.
BACKGROUND: Healthcare-associated infections (HAIs) pose a serious risk to patient safety and quality of care. The Canadian Nosocomial Infection Surveillance Program (CNISP) conducts national surveillance of HAIs at sentinel acute-care hospitals across Canada. This report provides an overview of 10 years of Canadian data on the epidemiology of select device-associated HAIs. METHODS: Over 40 hospitals submitted data between 2009 and 2018 for hip and knee surgical site infections (SSIs), cerebrospinal fluid shunt SSIs, paediatric cardiac SSIs and/or central line-associated bloodstream infections (CLABSIs). Counts, rates, patient and hospital characteristics, as well as pathogen distributions and antimicrobial susceptibilities are presented. RESULTS: A total of 4,300 device-associated infections were reported. Central line-associated bloodstream infections were the most common device-associated HAI reported (n=2,973, 69%) and hip and knee arthroplasty infections were the most common SSIs reported (66% of SSIs). Our findings show decreasing CLABSI rates in neonatal intensive care units (4.2 to 1.9 per 1,000 line-days, p<0.0001) and decreasing knee SSI rates (0.69 to 0.30 infections per 100 surgeries, p=0.007). Rates of device-associated HAIs have remained relatively consistent over the 10-year surveillance period. Overall, 4,599 pathogens were identified from device-associated HAI; 70% of these were related to CLABSIs. Coagulase-negative staphylococci (29%) and Staphylococcus aureus (14%) were the most frequently reported pathogens. Gram-positive pathogens represented 68% of identified pathogens, gram-negative pathogens represented 22% and fungi represented 9%. CONCLUSION: Understanding the national burden of device-associated HAIs is essential for developing and maintaining benchmark rates for informing infection and prevention control and antimicrobial stewardship policies and programs.
Authors: Lindsey M Weiner-Lastinger; Sheila Abner; Jonathan R Edwards; Alexander J Kallen; Maria Karlsson; Shelley S Magill; Daniel Pollock; Isaac See; Minn M Soe; Maroya S Walters; Margaret A Dudeck Journal: Infect Control Hosp Epidemiol Date: 2019-11-26 Impact factor: 3.254
Authors: Víctor Daniel Rosenthal; Hail M Al-Abdely; Amani Ali El-Kholy; Safa A Aziz AlKhawaja; Hakan Leblebicioglu; Yatin Mehta; Vineya Rai; Nguyen Viet Hung; Souha Sami Kanj; Mona Foda Salama; Estuardo Salgado-Yepez; Naheed Elahi; Rayo Morfin Otero; Anucha Apisarnthanarak; Braulio Matias De Carvalho; Bat Erdene Ider; Dale Fisher; Maria Carmen S G Buenaflor; Michael M Petrov; Ana Marcela Quesada-Mora; Farid Zand; Vaidotas Gurskis; Tanja Anguseva; Aamer Ikram; Daisy Aguilar de Moros; Wieslawa Duszynska; Nepomuceno Mejia; Florin George Horhat; Vladislav Belskiy; Vesna Mioljevic; Gabriela Di Silvestre; Katarina Furova; Gloria Y Ramos-Ortiz; May Osman Gamar Elanbya; Hindra Irawan Satari; Umesh Gupta; Tarek Dendane; Lul Raka; Humberto Guanche-Garcell; Bijie Hu; Denis Padgett; Kushlani Jayatilleke; Najla Ben Jaballah; Eleni Apostolopoulou; Walter Enrique Prudencio Leon; Alejandra Sepulveda-Chavez; Hector Miguel Telechea; Andrew Trotter; Carlos Alvarez-Moreno; Luis Kushner-Davalos Journal: Am J Infect Control Date: 2016-10-11 Impact factor: 2.918
Authors: J Macher; C Gras Le Guen; A Chenouard; J M Liet; B Gaillard Le Roux; A Legrand; J Mahuet; E Launay; V Gournay; N Joram Journal: Pediatr Cardiol Date: 2016-11-14 Impact factor: 1.655
Authors: M Abbas; E Aghayev; N Troillet; M-C Eisenring; S P Kuster; A F Widmer; S Harbarth Journal: J Hosp Infect Date: 2017-10-06 Impact factor: 3.926
Authors: Christopher E Kandel; Richard Jenkinson; Nick Daneman; David Backstein; Bettina E Hansen; Matthew P Muller; Kevin C Katz; Jessica Widdifield; Earl Bogoch; Sarah Ward; Abhilash Sajja; Felipe Garcia Jeldes; Allison McGeer Journal: Open Forum Infect Dis Date: 2019-10-21 Impact factor: 3.835