Víctor Daniel Rosenthal1, Hail M Al-Abdely2, Amani Ali El-Kholy3, Safa A Aziz AlKhawaja4, Hakan Leblebicioglu5, Yatin Mehta6, Vineya Rai7, Nguyen Viet Hung8, Souha Sami Kanj9, Mona Foda Salama10, Estuardo Salgado-Yepez11, Naheed Elahi12, Rayo Morfin Otero13, Anucha Apisarnthanarak14, Braulio Matias De Carvalho15, Bat Erdene Ider16, Dale Fisher17, Maria Carmen S G Buenaflor18, Michael M Petrov19, Ana Marcela Quesada-Mora20, Farid Zand21, Vaidotas Gurskis22, Tanja Anguseva23, Aamer Ikram24, Daisy Aguilar de Moros25, Wieslawa Duszynska26, Nepomuceno Mejia27, Florin George Horhat28, Vladislav Belskiy29, Vesna Mioljevic30, Gabriela Di Silvestre31, Katarina Furova32, Gloria Y Ramos-Ortiz33, May Osman Gamar Elanbya34, Hindra Irawan Satari35, Umesh Gupta36, Tarek Dendane37, Lul Raka38, Humberto Guanche-Garcell39, Bijie Hu40, Denis Padgett41, Kushlani Jayatilleke42, Najla Ben Jaballah43, Eleni Apostolopoulou44, Walter Enrique Prudencio Leon45, Alejandra Sepulveda-Chavez46, Hector Miguel Telechea47, Andrew Trotter48, Carlos Alvarez-Moreno49, Luis Kushner-Davalos50. 1. International Nosocomial Infection Control Consortium, Buenos Aires, Argentina. Electronic address: victor_rosenthal@inicc.org. 2. General Directorate of Infection Prevention and Control, Ministry of Health, Saudi Arabia. 3. Cairo University Hospital, Cairo; Dar Al Fouad Hospital, 6th of October City, Egypt. 4. General Directorate of Infection Prevention and Control, Ministry of Health, Bahrain. 5. Ondokuz Mayis University Medical School, Samsun, Turkey. 6. Medanta The Medicity, New Delhi, India. 7. University Malaya Medical Centre, Kuala Lumpur, Malaysia. 8. Bach Mai Hospital, Hanoi, Vietnam. 9. American University of Beirut Medical Center, Beirut, Lebanon. 10. Mubarak Al Kabir Hospital, Kuwait City, Kuwait. 11. Clínica La Merced, Quito, Ecuador. 12. Dubai Hospital, Dubai, United Arab Emirates. 13. Hospital Civil de Guadalajara Fray Antonio Alcalde Infection Control Committee, Guadalajara, Mexico. 14. Thammasat University Hospital, Pratumthani, Thailand. 15. Hospital de Messejana, Fortaleza, Brazil. 16. Intermed Hospital, Ulaanbaatar, Mongolia. 17. National University Hospital Singapore, Singapore, Singapore. 18. Philippine Heart Center, Manila, Philippines. 19. St George University Hospital, Plovdiv, Bulgaria. 20. Hospital Clínica Bíblica, San Jose, Costa Rica. 21. Nemazee Hospital Shiraz University of Medical Sciences, Shiraz, Iran. 22. Hospital of Lithuanian University of Health Sciences Kauno Klinikos, Kaunas, Lithuania. 23. Special Hospital for Surgical Diseases Filip Vtori, Skopje, Macedonia. 24. Armed Forces Institute of Pathology, Rawalpindi, Pakistan. 25. Hospital del Niño de Panama, Panama. 26. Wroclaw University Hospital, Wroclaw, Poland. 27. Hospital General de La Plaza de La Salud, Santo Domingo, Dominican Republic. 28. University of Medicine and Pharmacy Victor Babes Timisoara Emergency County Clinical Hospital, Timisoara, Romania. 29. Privolzhskiy District Medical Center, Nizhniy Novgorod, Russia. 30. Clinical Center of Serbia, Belgrade, Serbia. 31. Hospital de Clínicas Caracas, Caracas, Venezuela. 32. Catholic University in Ruzomberok Faculty Of Health Central Military Hospital Ruzomberok, Ruzomberok, Slovakia. 33. Hospital Episcopal San Lucas, Guayama, Puerto Rico. 34. Bahry Teaching Hospital, Khartoum, Sudan. 35. Ciptomangunkusumo, Jakarta, Indonesia. 36. Port Moresby General Hospital, Port Moresby, Papua New Guinea. 37. Ibn Sina Hospital of Morocco, Rabat, Morocco. 38. National Institute for Public Health of Kosovo and Medical School, Prishtina University, Prishtina, Kosovo. 39. Joaquin Albarran, La Habana, Cuba. 40. Zhongshan Hospital, Fudan University, Shanghai, China. 41. Hospital De Especialidades Del Instituto Hondureno De Seguridad Social, Tegucigalpa, Honduras. 42. Sri Jayewardenepura General Hospital, Nugegoda, Sri Lanka. 43. Children Hospital Bechir Hamza of Tunis, Tunis, Tunisia. 44. General and Oncological Hospital of Kiffissia, Athens, Greece. 45. Hospital Central De La Fuerza Aerea Del Peru, Lima, Peru. 46. Clínica Sanatorio Alemán, Concepcion, Chile. 47. Centro Hospitalario Pereira Rossell, Montevideo, Uruguay. 48. Grande International Hospital, Kathmandu, Nepal. 49. Pontificia Universidad Javeriana Hospital Universitario San Ignacio, Bogotá, Colombia. 50. Caja de Salud De La Banca, La Paz, Bolivia.
Abstract
BACKGROUND: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. METHODS: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. RESULTS: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. CONCLUSIONS: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically. Copyright Â
BACKGROUND: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. METHODS: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. RESULTS: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. CONCLUSIONS: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically. Copyright Â
Authors: Jeffrey A Alten; A K M Fazlur Rahman; Hayden J Zaccagni; Andrew Shin; David S Cooper; Joshua J Blinder; Lauren Retzloff; Inmaculada B Aban; Eric M Graham; Jeffrey Zampi; Yuliya Domnina; Michael G Gaies Journal: Pediatr Infect Dis J Date: 2018-08 Impact factor: 2.129
Authors: Jean-François Timsit; Matteo Bassetti; Olaf Cremer; George Daikos; Jan de Waele; Andre Kallil; Eric Kipnis; Marin Kollef; Kevin Laupland; Jose-Artur Paiva; Jesús Rodríguez-Baño; Étienne Ruppé; Jorge Salluh; Fabio Silvio Taccone; Emmanuel Weiss; François Barbier Journal: Intensive Care Med Date: 2019-01-18 Impact factor: 17.440