Literature DB >> 33442676

Federated Learning used for predicting outcomes in SARS-COV-2 patients.

Mona Flores, Ittai Dayan, Holger Roth, Aoxiao Zhong, Ahmed Harouni, Amilcare Gentili, Anas Abidin, Andrew Liu, Anthony Costa, Bradford Wood, Chien-Sung Tsai, Chih-Hung Wang, Chun-Nan Hsu, C K Lee, Colleen Ruan, Daguang Xu, Dufan Wu, Eddie Huang, Felipe Kitamura, Griffin Lacey, Gustavo César de Antônio Corradi, Hao-Hsin Shin, Hirofumi Obinata, Hui Ren, Jason Crane, Jesse Tetreault, Jiahui Guan, John Garrett, Jung Gil Park, Keith Dreyer, Krishna Juluru, Kristopher Kersten, Marcio Aloisio Bezerra Cavalcanti Rockenbach, Marius Linguraru, Masoom Haider, Meena AbdelMaseeh, Nicola Rieke, Pablo Damasceno, Pedro Mario Cruz E Silva, Pochuan Wang, Sheng Xu, Shuichi Kawano, Sira Sriswa, Soo Young Park, Thomas Grist, Varun Buch, Watsamon Jantarabenjakul, Weichung Wang, Won Young Tak, Xiang Li, Xihong Lin, Fred Kwon, Fiona Gilbert, Josh Kaggie, Quanzheng Li, Abood Quraini, Andrew Feng, Andrew Priest, Baris Turkbey, Benjamin Glicksberg, Bernardo Bizzo, Byung Seok Kim, Carlos Tor-Diez, Chia-Cheng Lee, Chia-Jung Hsu, Chin Lin, Chiu-Ling Lai, Christopher Hess, Colin Compas, Deepi Bhatia, Eric Oermann, Evan Leibovitz, Hisashi Sasaki, Hitoshi Mori, Isaac Yang, Jae Ho Sohn, Krishna Nand Keshava Murthy, Li-Chen Fu, Matheus Ribeiro Furtado de Mendonça, Mike Fralick, Min Kyu Kang, Mohammad Adil, Natalie Gangai, Peerapon Vateekul, Pierre Elnajjar, Sarah Hickman, Sharmila Majumdar, Shelley McLeod, Sheridan Reed, Stefan Graf, Stephanie Harmon, Tatsuya Kodama, Thanyawee Puthanakit, Tony Mazzulli, Vitor de Lima Lavor, Yothin Rakvongthai, Yu Rim Lee, Yuhong Wen.   

Abstract

'Federated Learning' (FL) is a method to train Artificial Intelligence (AI) models with data from multiple sources while maintaining anonymity of the data thus removing many barriers to data sharing. During the SARS-COV-2 pandemic, 20 institutes collaborated on a healthcare FL study to predict future oxygen requirements of infected patients using inputs of vital signs, laboratory data, and chest x-rays, constituting the "EXAM" (EMR CXR AI Model) model. EXAM achieved an average Area Under the Curve (AUC) of over 0.92, an average improvement of 16%, and a 38% increase in generalisability over local models. The FL paradigm was successfully applied to facilitate a rapid data science collaboration without data exchange, resulting in a model that generalised across heterogeneous, unharmonized datasets. This provided the broader healthcare community with a validated model to respond to COVID-19 challenges, as well as set the stage for broader use of FL in healthcare.

Entities:  

Year:  2021        PMID: 33442676      PMCID: PMC7805458          DOI: 10.21203/rs.3.rs-126892/v1

Source DB:  PubMed          Journal:  Res Sq


  34 in total

1.  Harmonization of detailed clinical models with clinical study data standards.

Authors:  G Jiang; J Evans; T A Oniki; J F Coyle; L Bain; S M Huff; R D Kush; C G Chute
Journal:  Methods Inf Med       Date:  2014-11-26       Impact factor: 2.176

2.  Keep up with the latest coronavirus research.

Authors:  Qingyu Chen; Alexis Allot; Zhiyong Lu
Journal:  Nature       Date:  2020-03       Impact factor: 49.962

3.  A Commitment to Open Source in Neuroscience.

Authors:  Padraig Gleeson; Andrew P Davison; R Angus Silver; Giorgio A Ascoli
Journal:  Neuron       Date:  2017-12-06       Impact factor: 17.173

4.  Management of COVID-19 Respiratory Distress.

Authors:  John J Marini; Luciano Gattinoni
Journal:  JAMA       Date:  2020-06-09       Impact factor: 56.272

5.  A clinical risk score to identify patients with COVID-19 at high risk of critical care admission or death: An observational cohort study.

Authors:  James B Galloway; Sam Norton; Richard D Barker; Andrew Brookes; Ivana Carey; Benjamin D Clarke; Raeesa Jina; Carole Reid; Mark D Russell; Ruth Sneep; Leah Sugarman; Sarah Williams; Mark Yates; James Teo; Ajay M Shah; Fleur Cantle
Journal:  J Infect       Date:  2020-05-29       Impact factor: 6.072

6.  Federated learning in medicine: facilitating multi-institutional collaborations without sharing patient data.

Authors:  Micah J Sheller; Brandon Edwards; G Anthony Reina; Jason Martin; Sarthak Pati; Aikaterini Kotrotsou; Mikhail Milchenko; Weilin Xu; Daniel Marcus; Rivka R Colen; Spyridon Bakas
Journal:  Sci Rep       Date:  2020-07-28       Impact factor: 4.379

Review 7.  Putting the data before the algorithm in big data addressing personalized healthcare.

Authors:  Eli M Cahan; Tina Hernandez-Boussard; Sonoo Thadaney-Israni; Daniel L Rubin
Journal:  NPJ Digit Med       Date:  2019-08-19

8.  Respiratory support for adult patients with COVID-19.

Authors:  Jessica S Whittle; Ivan Pavlov; Alfred D Sacchetti; Charles Atwood; Mark S Rosenberg
Journal:  J Am Coll Emerg Physicians Open       Date:  2020-04-13

9.  Patient characteristics and admitting vital signs associated with coronavirus disease 2019 (COVID-19)-related mortality among patients admitted with noncritical illness.

Authors:  Kenneth E Sands; Richard P Wenzel; Laura E McLean; Kimberly M Korwek; Jonathon D Roach; Karla M Miller; Russell E Poland; L Hayley Burgess; Edmund S Jackson; Jonathan B Perlin
Journal:  Infect Control Hosp Epidemiol       Date:  2020-09-15       Impact factor: 3.254

Review 10.  The future of digital health with federated learning.

Authors:  Nicola Rieke; Jonny Hancox; Wenqi Li; Fausto Milletarì; Holger R Roth; Shadi Albarqouni; Spyridon Bakas; Mathieu N Galtier; Bennett A Landman; Klaus Maier-Hein; Sébastien Ourselin; Micah Sheller; Ronald M Summers; Andrew Trask; Daguang Xu; Maximilian Baust; M Jorge Cardoso
Journal:  NPJ Digit Med       Date:  2020-09-14
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