Julia E Wiedmeier1, Luke J Mountjoy2,3, Matthew R Buras4, Heidi E Kosiorek4, Kyle E Coppola5, Patricia M Verona6, Curtiss B Cook7, Nina J Karlin2,5. 1. Department of Internal Medicine, Mayo Clinic Hospital, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA. 2. Division of Hematology & Medical Oncology, Mayo Clinic Hospital, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA. 3. Colorado Blood Cancer Institute, 1721 E 19th Ave, Suites 200-300, Denver, CO 80218, USA. 4. Biostatistics, Mayo Clinic, 13400 E. SheaBlvd., Scottsdale, AZ 85259, USA. 5. Mayo Clinic Cancer Center, Mayo Clinic, 13400 E. Shea Blvd., Scottsdale, AZ 85259, USA. 6. Enterprise Technology Services, Mayo Clinic Hospital, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA. 7. Division of Endocrinology, Mayo Clinic, 13400 E. Shea Blvd., Scottsdale, AZ 85259, USA.
Abstract
AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007-2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan-Meier method. Hemoglobin A1c and glucose levels the year after leukemia diagnosis were compared by mixed models. RESULTS: Among 25 of 70 patients with diabetes, mean hemoglobin A1c during the year after leukemia diagnosis was 6.8%. Kaplan-Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79). CONCLUSION: No associations were found between leukemia, diabetes, survival and glycemic control.
AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007-2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan-Meier method. Hemoglobin A1c and glucose levels the year after leukemia diagnosis were compared by mixed models. RESULTS: Among 25 of 70 patients with diabetes, mean hemoglobin A1c during the year after leukemia diagnosis was 6.8%. Kaplan-Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79). CONCLUSION: No associations were found between leukemia, diabetes, survival and glycemic control.
Authors: Khanh Vu; Naifa Busaidy; Maria E Cabanillas; Marina Konopleva; Stefan Faderl; Deborah A Thomas; Susan O'Brien; Kristine Broglio; Joe Ensor; Carmen Escalante; Michael Andreeff; Hagop Kantarjian; Victor Lavis; Sai-Ching Jim Yeung Journal: Clin Lymphoma Myeloma Leuk Date: 2012-06-01
Authors: Steven S Coughlin; Eugenia E Calle; Lauren R Teras; Jennifer Petrelli; Michael J Thun Journal: Am J Epidemiol Date: 2004-06-15 Impact factor: 4.897
Authors: S Scotland; E Saland; N Skuli; F de Toni; H Boutzen; E Micklow; I Sénégas; R Peyraud; L Peyriga; F Théodoro; E Dumon; Y Martineau; G Danet-Desnoyers; F Bono; C Rocher; T Levade; S Manenti; C Junot; J-C Portais; N Alet; C Récher; M A Selak; M Carroll; J-E Sarry Journal: Leukemia Date: 2013-04-09 Impact factor: 11.528