Literature DB >> 33436678

Novel CFD modeling approaches to assessing urine flow in prostatic urethra after transurethral surgery.

Bin Zhang1,2, Shuang Liu1, Yinxia Liu3, Bo Wu1, Xuhui Zhang1, Xin Wang1, Xuezhi Liang1, Xiaoming Cao1, Dongwen Wang4,5, Chin-Lee Wu2,6.   

Abstract

Assessment of the pressure and velocity of urine flow for different diameter ratios of prostatic urethra (RPU) after transurethral surgery using computational fluid dynamics (CFD). A standardized and idealized two-dimensional CFD model after transurethral surgery (CATS-1st) was developed for post-surgery mid-voiding. Using CATS-1st, 210 examples were amplified according to an array of size [3][5][14], which contained three groups of longitudinal diameters of prostatic urethra (LD-PU). Each of these groups contained five subgroups of transverse diameters of the bladder neck (TD-BN), each with 14 examples of transverse diameters of PU (TD-PU). The pressure and velocity of urine flow were monitored through flow dynamics simulation, and the relationship among RPU-1 (TD-PU/TD-BN), RPU-2 (RPU-1/LD-PU), the transverse diameter of the vortex, and the midpoint velocity of the external urethral orifice (MV-EUO) was determined. A total of 210 CATS examples, including CATS-1st examples, were analyzed. High (bladder and PU) and medium/low (the rest of the urethra) pressure zones, and low (bladder), medium (PU), and high (the rest of the urethra) velocity zones were determined. The rapid changes in the velocity were concentrated in and around the PU. Laminar flow was present in all the examples. The vortices appeared and then gradually shrank with reducing RPU on both the sides of PU in 182 examples. In the vortex examples, minimum RPU-1 and RPU-2 reached close to the values of 0.79 and 0.02, respectively. MV-EUO increased gradually with decreasing RPU. In comparison to the vortex examples, the non-vortex examples exhibited a significantly higher (p < 0.01) MV-EUO. The developed CFD models (CATS) presented an effective simulation of urine flow behavior within the PU after transurethral surgery for benign prostatic hyperplasia (BPH). These models could prove to be useful for morphological repair in PU after transurethral surgery.

Entities:  

Year:  2021        PMID: 33436678      PMCID: PMC7804846          DOI: 10.1038/s41598-020-79505-6

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  22 in total

1.  Development of a CFD urethral model to study flow-generated vortices under different conditions of prostatic obstruction.

Authors:  Johan J M Pel; Ron van Mastrigt
Journal:  Physiol Meas       Date:  2006-11-17       Impact factor: 2.833

2.  Urethra actively opens from the very beginning of micturition: a new concept of urethral function.

Authors:  Hiroki Watanabe; Satoru Takahashi; Osamu Ukimura
Journal:  Int J Urol       Date:  2013-07-30       Impact factor: 3.369

3.  Computational Fluid Dynamic Modeling of Urethral Strictures.

Authors:  Andrew J Cohen; Nima Baradaran; Jorge Mena; Daniel Krsmanovich; Benjamin N Breyer
Journal:  J Urol       Date:  2019-07-08       Impact factor: 7.450

4.  Fluid dynamic assessment of the lower urinary tract: Exploratory research to observe vorticity in the prostatic urethra after transurethral enucleation.

Authors:  Tomonori Minagawa; Teruyuki Ogawa; Osamu Ishizuka
Journal:  Int J Urol       Date:  2019-05-30       Impact factor: 3.369

5.  Magnetic resonance imaging of benign prostatic hyperplasia.

Authors:  Serkan Guneyli; Emily Ward; Stephen Thomas; Ambereen Nehal Yousuf; Igor Trilisky; Yahui Peng; Tatjana Antic; Aytekin Oto
Journal:  Diagn Interv Radiol       Date:  2016 May-Jun       Impact factor: 2.630

6.  Vector Flow Visualization of Urinary Flow Dynamics in a Bladder Outlet Obstruction Model.

Authors:  Takuro Ishii; Billy Y S Yiu; Alfred C H Yu
Journal:  Ultrasound Med Biol       Date:  2017-08-19       Impact factor: 2.998

7.  Urine Flow Dynamics Through Prostatic Urethra With Tubular Organ Modeling Using Endoscopic Imagery.

Authors:  Takuro Ishii; Yoichi Kambara; Tomonori Yamanishi; Yukio Naya; Tatsuo Igarashi
Journal:  IEEE J Transl Eng Health Med       Date:  2014-08-04       Impact factor: 3.316

Review 8.  Computational medical imaging and hemodynamics framework for functional analysis and assessment of cardiovascular structures.

Authors:  Kelvin K L Wong; Defeng Wang; Jacky K L Ko; Jagannath Mazumdar; Thu-Thao Le; Dhanjoo Ghista
Journal:  Biomed Eng Online       Date:  2017-03-21       Impact factor: 2.819

9.  Assessment of posterior urethra in benign prostatic hyperplasia and after its surgery.

Authors:  Vivek Agrawal; Rahul Khullar; Ashesh Kumar Jha
Journal:  Urol Ann       Date:  2020-01-13

10.  The shape of the urine stream--from biophysics to diagnostics.

Authors:  Andrew P S Wheeler; Samir Morad; Noor Buchholz; Martin M Knight
Journal:  PLoS One       Date:  2012-10-16       Impact factor: 3.240

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  1 in total

1.  Computational fluid dynamics modeling approaches to assess lower urinary tract hydraulic dynamics in posterior urethral valve before and after endoscopic valve ablation: a pilot study.

Authors:  Hong-Song Chen; Xing Liu; Zhi-Cheng Zhang; Zi-Han Ye; Tao Lin; Da-Wei He; Guang-Hui Wei
Journal:  World J Urol       Date:  2021-11-22       Impact factor: 4.226

  1 in total

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