Literature DB >> 33433882

FTLD Treatment: Current Practice and Future Possibilities.

Peter A Ljubenkov1, Adam L Boxer2.   

Abstract

While behavioral variant frontotemporal dementia (bvFTD) and primary progressive aphasia (PPA) remain unrelenting and universally fatal conditions, there is a framework for supportive treatment in patients diagnosed with these frontotemporal dementia (FTD) syndromes and the larger spectrum of clinical syndromes associated with frontotemporal lobar degeneration (FTLD) pathology on autopsy. A managing physician has an important role in weighing therapeutic options, organizing caregiver support, and framing long-term expectations for patients and caregivers. Additionally, a dedicated neurologist may assist patients and caregivers in navigating a growing range of FTD research, including exciting opportunities in clinical therapeutic trials. This chapter will review current therapeutic options for patients with bvFTD and PPA and detail the landscape of potential new disease-modifying therapies targeting the pathophysiology or FTLD.

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Mesh：

Year:  2021        PMID： 33433882     DOI： 10.1007/978-3-030-51140-1_18

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  55 in total

1.  Classification of primary progressive aphasia and its variants.

Authors:  M L Gorno-Tempini; A E Hillis; S Weintraub; A Kertesz; M Mendez; S F Cappa; J M Ogar; J D Rohrer; S Black; B F Boeve; F Manes; N F Dronkers; R Vandenberghe; K Rascovsky; K Patterson; B L Miller; D S Knopman; J R Hodges; M M Mesulam; M Grossman
Journal:  Neurology       Date:  2011-02-16       Impact factor: 9.910

2.  Clinicopathological correlations in corticobasal degeneration.

Authors:  Suzee E Lee; Gil D Rabinovici; Mary Catherine Mayo; Stephen M Wilson; William W Seeley; Stephen J DeArmond; Eric J Huang; John Q Trojanowski; Matthew E Growdon; Jung Y Jang; Manu Sidhu; Tricia M See; Anna M Karydas; Maria-Luisa Gorno-Tempini; Adam L Boxer; Michael W Weiner; Michael D Geschwind; Katherine P Rankin; Bruce L Miller
Journal:  Ann Neurol       Date:  2011-08       Impact factor: 10.422

Review 3.  Management of neuropsychiatric symptoms of dementia in clinical settings: recommendations from a multidisciplinary expert panel.

Authors:  Helen C Kales; Laura N Gitlin; Constantine G Lyketsos
Journal:  J Am Geriatr Soc       Date:  2014-03-17       Impact factor: 5.562

Review 4.  Responding to safety issues in frontotemporal dementias.

Authors:  K A Talerico; L K Evans
Journal:  Neurology       Date:  2001-06       Impact factor: 9.910

5.  Behavioral Evolution of Progressive Semantic Aphasia in Comparison with Nonfluent Aphasia.

Authors:  Estrella Gómez-Tortosa; Ricardo Rigual; Cristina Prieto-Jurczynska; Ignacio Mahillo-Fernández; Rosa Guerrero-López; Julián Pérez-Pérez; M José Sainz
Journal:  Dement Geriatr Cogn Disord       Date:  2015-10-02       Impact factor: 2.959

6.  Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Authors:  K B Casaletto; A M Staffaroni; A Wolf; B Appleby; D Brushaber; G Coppola; B Dickerson; K Domoto-Reilly; F M Elahi; J Fields; J C Fong; L Forsberg; N Ghoshal; N Graff-Radford; M Grossman; H W Heuer; G-Y Hsiung; E D Huey; D Irwin; K Kantarci; D Kaufer; D Kerwin; D Knopman; J Kornak; J H Kramer; I Litvan; I R Mackenzie; M Mendez; B Miller; R Rademakers; E M Ramos; K Rascovsky; E D Roberson; J A Syrjanen; M C Tartaglia; S Weintraub; B Boeve; A L Boxer; H Rosen; K Yaffe
Journal:  Alzheimers Dement       Date:  2020-01       Impact factor: 21.566

Review 7.  A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia.

Authors:  Edward D Huey; Karen T Putnam; Jordan Grafman
Journal:  Neurology       Date:  2006-01-10       Impact factor: 9.910

8.  Retraining speech production and fluency in non-fluent/agrammatic primary progressive aphasia.

Authors:  Maya L Henry; H Isabel Hubbard; Stephanie M Grasso; Maria Luisa Mandelli; Stephen M Wilson; Mithra T Sathishkumar; Julius Fridriksson; Wylin Daigle; Adam L Boxer; Bruce L Miller; Maria Luisa Gorno-Tempini
Journal:  Brain       Date:  2018-06-01       Impact factor: 13.501

9.  Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria.

Authors:  Günter U Höglinger; Gesine Respondek; Maria Stamelou; Carolin Kurz; Keith A Josephs; Anthony E Lang; Brit Mollenhauer; Ulrich Müller; Christer Nilsson; Jennifer L Whitwell; Thomas Arzberger; Elisabet Englund; Ellen Gelpi; Armin Giese; David J Irwin; Wassilios G Meissner; Alexander Pantelyat; Alex Rajput; John C van Swieten; Claire Troakes; Angelo Antonini; Kailash P Bhatia; Yvette Bordelon; Yaroslau Compta; Jean-Christophe Corvol; Carlo Colosimo; Dennis W Dickson; Richard Dodel; Leslie Ferguson; Murray Grossman; Jan Kassubek; Florian Krismer; Johannes Levin; Stefan Lorenzl; Huw R Morris; Peter Nestor; Wolfgang H Oertel; Werner Poewe; Gil Rabinovici; James B Rowe; Gerard D Schellenberg; Klaus Seppi; Thilo van Eimeren; Gregor K Wenning; Adam L Boxer; Lawrence I Golbe; Irene Litvan
Journal:  Mov Disord       Date:  2017-05-03       Impact factor: 10.338

Review 10.  Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies.

Authors:  Kay Deckers; Martin P J van Boxtel; Olga J G Schiepers; Marjolein de Vugt; Juan Luis Muñoz Sánchez; Kaarin J Anstey; Carol Brayne; Jean-Francois Dartigues; Knut Engedal; Miia Kivipelto; Karen Ritchie; John M Starr; Kristine Yaffe; Kate Irving; Frans R J Verhey; Sebastian Köhler
Journal:  Int J Geriatr Psychiatry       Date:  2014-12-12       Impact factor: 3.485
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  3 in total

Review 1.  Behavioral Variant Frontotemporal Dementia.

Authors:  Bradley F Boeve
Journal:  Continuum (Minneap Minn)       Date:  2022-06-01

2.  Knowledge and Attitudes for the Management of Behavioral Variant of Frontotemporal Dementia.

Authors:  Sheila Castro-Suarez; Erik Guevara-Silva; César Caparó-Zamalloa; Victor Osorio-Marcatinco; Maria Meza-Vega; Bruce Miller; Mario Cornejo-Olivas
Journal:  Front Neurol       Date:  2022-01-11       Impact factor: 4.003

Review 3.  Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid.

Authors:  Shraddha S Sadekar; Mayumi Bowen; Hao Cai; Samira Jamalian; Hanine Rafidi; Whitney Shatz-Binder; Julien Lafrance-Vanasse; Pamela Chan; William J Meilandt; Amy Oldendorp; Alavattam Sreedhara; Ann Daugherty; Susan Crowell; Kristin R Wildsmith; Jasvinder Atwal; Reina N Fuji; Joshua Horvath
Journal:  Clin Pharmacol Ther       Date:  2022-02-23       Impact factor: 6.903
  3 in total

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