T O Vilz, J C Kalff, B Stoffels1. 1. Klinik und Poliklinik für Allgemein‑, Viszeral‑, Thorax- und Gefäßchirurgie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland. burkhard.stoffels@ukbonn.de.
Abstract
BACKGROUND: Indocyanine green (ICG) fluorescence imaging is increasingly being used in various areas of abdominal surgery. The constant improvement in the technology enables easy intraoperative use and progressively influences operative decision-making, also in robotically assisted colorectal surgery. OBJECTIVE: Summation of current evidence on the use of ICG fluorescence imaging in robotically assisted colorectal surgery. MATERIAL AND METHODS: The assessment of evidence is based on a comprehensive literature search (PubMed). RESULTS: First individual studies (feasibility, case matched, prospective cohort, multicenter phase II, single center randomized controlled study/trial) showed a significant reduction in the incidence of anastomotic leakage (AL) after colorectal anastomosis through the use of ICG fluorescence angiography (FA, 9.1% vs. 16.3%; p = 0.04). First feasibility studies demonstrated lymph node detection or navigation as well as ureter visualization. CONCLUSION: The ICG-FA reliably detects tissue perfusion, quickly and effectively with few side effects. It can influence intraoperative decision-making and reduce AL rates. In addition, patients may be offered more precise tumor therapy via ICG sentinel lymph node (SLN) detection and lateral pelvic lymph node (LPN) mapping and navigation. Iatrogenic lesions, such as ureteral injuries can be sufficiently prevented by appropriate visualization; however, valid data in order to be able to derive standardized operative consequences require further convincing multicenter, randomized controlled trials (mRCT).
BACKGROUND: Indocyanine green (ICG) fluorescence imaging is increasingly being used in various areas of abdominal surgery. The constant improvement in the technology enables easy intraoperative use and progressively influences operative decision-making, also in robotically assisted colorectal surgery. OBJECTIVE: Summation of current evidence on the use of ICG fluorescence imaging in robotically assisted colorectal surgery. MATERIAL AND METHODS: The assessment of evidence is based on a comprehensive literature search (PubMed). RESULTS: First individual studies (feasibility, case matched, prospective cohort, multicenter phase II, single center randomized controlled study/trial) showed a significant reduction in the incidence of anastomotic leakage (AL) after colorectal anastomosis through the use of ICG fluorescence angiography (FA, 9.1% vs. 16.3%; p = 0.04). First feasibility studies demonstrated lymph node detection or navigation as well as ureter visualization. CONCLUSION: The ICG-FA reliably detects tissue perfusion, quickly and effectively with few side effects. It can influence intraoperative decision-making and reduce AL rates. In addition, patients may be offered more precise tumor therapy via ICG sentinel lymph node (SLN) detection and lateral pelvic lymph node (LPN) mapping and navigation. Iatrogenic lesions, such as ureteral injuries can be sufficiently prevented by appropriate visualization; however, valid data in order to be able to derive standardized operative consequences require further convincing multicenter, randomized controlled trials (mRCT).
Authors: S Q Ashraf; E M Burns; A Jani; S Altman; J D Young; C Cunningham; O Faiz; N J Mortensen Journal: Colorectal Dis Date: 2013-04 Impact factor: 3.788
Authors: Leonora S F Boogerd; Charlotte E S Hoogstins; Dennis P Schaap; Miranda Kusters; Henricus J M Handgraaf; Maxime J M van der Valk; Denise E Hilling; Fabian A Holman; Koen C M J Peeters; J Sven D Mieog; Cornelis J H van de Velde; Arantza Farina-Sarasqueta; Ineke van Lijnschoten; Bérénice Framery; André Pèlegrin; Marian Gutowski; Simon W Nienhuijs; Ignace H J T de Hingh; Grard A P Nieuwenhuijzen; Harm J T Rutten; Francoise Cailler; Jacobus Burggraaf; Alexander L Vahrmeijer Journal: Lancet Gastroenterol Hepatol Date: 2018-01-30
Authors: Wernard A A Borstlap; Emma Westerduin; Tjeerd S Aukema; Willem A Bemelman; Pieter J Tanis Journal: Ann Surg Date: 2017-11 Impact factor: 12.969
Authors: G Armstrong; J Croft; N Corrigan; J M Brown; V Goh; P Quirke; C Hulme; D Tolan; A Kirby; R Cahill; P R O'Connell; D Miskovic; M Coleman; D Jayne Journal: Colorectal Dis Date: 2018-06-08 Impact factor: 3.788