Literature DB >> 33432225

First small-molecule drug targeting RNA gains momentum.

Cormac Sheridan1.   

Abstract

Year:  2021        PMID: 33432225     DOI: 10.1038/s41587-020-00788-1

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN: 1087-0156            Impact factor:   54.908


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  6 in total

1.  SILCS-RNA: Toward a Structure-Based Drug Design Approach for Targeting RNAs with Small Molecules.

Authors:  Abhishek A Kognole; Anthony Hazel; Alexander D MacKerell
Journal:  J Chem Theory Comput       Date:  2022-08-01       Impact factor: 6.578

2.  Efficient NMR Screening Approach to Discover Small Molecule Fragments Binding Structured RNA.

Authors:  Matthew D Shortridge; Gabriele Varani
Journal:  ACS Med Chem Lett       Date:  2021-07-13       Impact factor: 4.632

Review 3.  Expression and functions of long non-coding RNA NEAT1 and isoforms in breast cancer.

Authors:  Erik Knutsen; Adrian L Harris; Maria Perander
Journal:  Br J Cancer       Date:  2021-10-20       Impact factor: 9.075

Review 4.  Programmable technologies to manipulate gene expression at the RNA level.

Authors:  Huachun Liu; Simone Rauch; Bryan C Dickinson
Journal:  Curr Opin Chem Biol       Date:  2021-04-27       Impact factor: 8.972

5.  Finding the Ion in the RNA-Stack: Can Computational Models Accurately Predict Key Functional Elements in Large Macromolecular Complexes?

Authors:  Marco Marcia; Jacopo Manigrasso; Marco De Vivo
Journal:  J Chem Inf Model       Date:  2021-06-16       Impact factor: 4.956

6.  In Vitro Evaluation of Bis-3-Chloropiperidines as RNA Modulators Targeting TAR and TAR-Protein Interaction.

Authors:  Alice Sosic; Giulia Olivato; Caterina Carraro; Richard Göttlich; Dan Fabris; Barbara Gatto
Journal:  Int J Mol Sci       Date:  2022-01-06       Impact factor: 5.923

  6 in total

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