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Literature DB >> 3342063

Giant polypeptides of skeletal muscle titin: sedimentation equilibrium in guanidine hydrochloride.

Abstract

Titin has been purified from rabbit skeletal myofibrils in guanidine hydrochloride by gel filtration on Sephacryl S-1000. The sedimentation coefficients of denatured titin in 6 M guanidine hydrochloride are highly concentration dependent and follow the equation: 1/S = 0.241 + 0.302 A280. Equilibrium sedimentation studies indicate that the average molecular weight of titin polypeptides is 2.4 to 2.6 X 10(6).

Entities: Chemical Gene Species

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Year: 1988 PMID： 3342063 DOI： 10.1016/0006-291x(88)90750-4

Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575

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Cited

24 in total

Review 1. Stretching and visualizing titin molecules: combining structure, dynamics and mechanics.

Authors: Miklós S Z Kellermayer; László Grama
Journal: J Muscle Res Cell Motil Date: 2002 Impact factor: 2.698

2. Immunoelectron microscopic epitope locations of titin in rabbit heart muscle.

Authors: S Pierobon-Bormioli; D Biral; R Betto; G Salviati
Journal: J Muscle Res Cell Motil Date: 1992-02 Impact factor: 2.698

3. Association of titin and myosin heavy chain in developing skeletal muscle.

Authors: W B Isaacs; I S Kim; A Struve; A B Fulton
Journal: Proc Natl Acad Sci U S A Date: 1992-08-15 Impact factor: 11.205

4. Characterization and localization of alpha-connectin (titin 1): an elastic protein isolated from rabbit skeletal muscle.

Authors: S Kimura; T Matsuura; S Ohtsuka; Y Nakauchi; A Matsuno; K Maruyama
Journal: J Muscle Res Cell Motil Date: 1992-02 Impact factor: 2.698

5. A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure.

Authors: E Shtivelman; F E Cohen; J M Bishop
Journal: Proc Natl Acad Sci U S A Date: 1992-06-15 Impact factor: 11.205

6. Regulation of skeletal muscle stiffness and elasticity by titin isoforms: a test of the segmental extension model of resting tension.

Authors: K Wang; R McCarter; J Wright; J Beverly; R Ramirez-Mitchell
Journal: Proc Natl Acad Sci U S A Date: 1991-08-15 Impact factor: 11.205

Giant polypeptides of skeletal muscle titin: sedimentation equilibrium in guanidine hydrochloride.

Review 1. Stretching and visualizing titin molecules: combining structure, dynamics and mechanics.

2. Immunoelectron microscopic epitope locations of titin in rabbit heart muscle.

3. Association of titin and myosin heavy chain in developing skeletal muscle.

4. Characterization and localization of alpha-connectin (titin 1): an elastic protein isolated from rabbit skeletal muscle.

5. A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure.

6. Regulation of skeletal muscle stiffness and elasticity by titin isoforms: a test of the segmental extension model of resting tension.

7. Primary structure of the kinase domain region of rabbit skeletal and cardiac muscle titin.

8. Identification and initial characterization of five Cryptosporidium parvum sporozoite antigen genes.

9. Characterization of beta-connectin (titin 2) from striated muscle by dynamic light scattering.

10. Passive force generation and titin isoforms in mammalian skeletal muscle.