Pierre A Coulombe1, Pekka Lappalainen2. 1. Department of Cell and Developmental Biology, University of Michigan Medical School, 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: coulombe@umich.edu. 2. HiLIFE Institute of Biotechnology, University of Helsinki, Biocenter 2, room 2016, Viikinkaari 5D, 00790 Helsinki, Finland. Electronic address: pekka.lappalainen@helsinki.fi.