| Literature DB >> 33415075 |
Julie Bennett1, Craig Erker2, Lucie Lafay-Cousin3, Vijay Ramaswamy1, Juliette Hukin4, Magimairajan I Vanan5, Sylvia Cheng4, Hallie Coltin6, Adriana Fonseca1, Donna Johnston6, Andrea Lo7, Shayna Zelcer8, Saima Alvi9, Lynette Bowes10, Josée Brossard11, Janie Charlebois11, David Eisenstat12, Kathleen Felton13, Adam Fleming14, Nada Jabado15, Valérie Larouche16, Geneviève Legault15, Chris Mpofu13, Sébastien Perreault17, Mariana Silva18, Roona Sinha13, Doug Strother3, Derek S Tsang19, Beverly Wilson12, Bruce Crooks2, Ute Bartels1.
Abstract
Primary CNS tumors are the leading cause of cancer-related death in pediatrics. It is essential to understand treatment trends to interpret national survival data. In Canada, children with CNS tumors are treated at one of 16 tertiary care centers. We surveyed pediatric neuro-oncologists to create a national standard of practice to be used in the absence of a clinical trial for seven of the most prevalent brain tumors in children. This allowed description of practice across the country, along with a consensus. This had a multitude of benefits, including understanding practice patterns, allowing for a basis to compare in future research and informing Health Canada of the current management of patients. This also allows all children in Canada to receive equivalent care, regardless of location.Entities:
Keywords: ependymoma; high grade glioma; low grade glioma; medulloblastoma; national strategy; pediatric neuro-oncology; standards
Year: 2020 PMID： 33415075 PMCID： PMC7783450 DOI： 10.3389/fonc.2020.593192
Source DB: PubMed Journal: Front Oncol ISSN： 2234-943X Impact factor: 6.244