Literature DB >> 33415043

Co-Existing Subaortic Stenosis in a Patient With Hypertrophic Obstructive Cardiomyopathy: A Rare and Interesting Finding.

Raja S Mushtaque1, Rabia Mushtaque1, Shahbano Baloch2.   

Abstract

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder leading to left ventricular outflow tract (LVOT) obstruction. It can present with chest pain, syncope, breathlessness, or it may cause sudden cardiac death in some cases. The echocardiography in most cases while cardiac CT or cardiac MRI in selected cases are the important diagnostic modalities to make the diagnosis of HCM. In this case report, we discuss a case of a young female patient previously diagnosed with HCM and presented with palpitations, chest pain, and shortness of breath. Her echocardiography revealed severe asymmetrically hypertrophied left ventricle (LV) with normal function, the systolic anterior motion of the mitral valve was present and a subvalvular aortic membrane was also seen. The CT was also performed showing severe asymmetrical hypertrophied septum and thickened trileaflet tricommissural aortic valve with no calcification or significant valvular aortic stenosis but there was a subaortic membrane (concentric only sparing anteriorly). The presence of subaortic membrane with HCM is a rare finding and it can be a diagnostic challenge and untreated cases are susceptible to progressive heart failure and worsening of the symptoms by further increasing LVOT obstruction. A thorough investigation and planning before surgical intervention is required to achieve optimal results.
Copyright © 2020, Mushtaque et al.

Entities:  

Keywords:  ash; hocm; lvoto; sam; subaortic membrane

Year:  2020        PMID: 33415043      PMCID: PMC7781779          DOI: 10.7759/cureus.11891

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  9 in total

1.  Subaortic membrane mimicking hypertrophic cardiomyopathy.

Authors:  Mark Joseph Anderson; Adelaide Arruda-Olson; Bernard Gersh; Jeffrey Geske
Journal:  BMJ Case Rep       Date:  2015-11-04

2.  Images in cardiovascular medicine. Subaortic membrane in the adult.

Authors:  John Alfred Carr; Lissa Sugeng; Lynn Weinert; Valluvan Jeevanandam; Roberto M Lang
Journal:  Circulation       Date:  2005-12-06       Impact factor: 29.690

Review 3.  Cardiology: hypertrophic cardiomyopathy.

Authors:  John Firth
Journal:  Clin Med (Lond)       Date:  2019-01       Impact factor: 2.659

Review 4.  Clinical Course and Management of Hypertrophic Cardiomyopathy.

Authors:  Barry J Maron
Journal:  N Engl J Med       Date:  2018-08-16       Impact factor: 91.245

5.  Echocardiography in coexisting hypertrophic subaortic stenosis and fixed left ventricular outflow obstruction.

Authors:  K J Chung; J A Manning; R Gramiak
Journal:  Circulation       Date:  1974-04       Impact factor: 29.690

6.  Hypertrophic cardiomyopathy and membranous subaortic stenosis: a rare, but possible association.

Authors:  Massimiliano Camilli; Maria C Meucci; Marco G Del Buono; Carolina Ierardi; Angelica B Delogu; Filippo Crea
Journal:  J Cardiovasc Med (Hagerstown)       Date:  2020-02       Impact factor: 2.160

7.  Underappreciated occurrence of discrete subaortic membranes producing left ventricular outflow obstruction in hypertrophic cardiomyopathy.

Authors:  Muhil Kannappan; Barry J Maron; Hassan Rastegar; Natesa G Pandian; Martin S Maron; Ethan J Rowin
Journal:  Echocardiography       Date:  2017-07-06       Impact factor: 1.724

Review 8.  Hypertrophic obstructive cardiomyopathy.

Authors:  Josef Veselka; Nandan S Anavekar; Philippe Charron
Journal:  Lancet       Date:  2016-11-30       Impact factor: 79.321

9.  Surgical outcome of discrete subaortic stenosis in adults: a multicenter study.

Authors:  Denise van der Linde; Jolien W Roos-Hesselink; Dimitris Rizopoulos; Helena J Heuvelman; Werner Budts; Arie P J van Dijk; Maarten Witsenburg; Sing C Yap; Angela Oxenius; Candice K Silversides; Erwin N Oechslin; Ad J J C Bogers; Johanna J M Takkenberg
Journal:  Circulation       Date:  2013-02-20       Impact factor: 29.690

  9 in total

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