Literature DB >> 33413073

A transfer learning model with multi-source domains for biomedical event trigger extraction.

Yifei Chen1.   

Abstract

BACKGROUND: Automatic extraction of biomedical events from literature, that allows for faster update of the latest discoveries automatically, is a heated research topic now. Trigger word recognition is a critical step in the process of event extraction. Its performance directly influences the results of the event extraction. In general, machine learning-based trigger recognition approaches such as neural networks must to be trained on a dataset with plentiful annotations to achieve high performances. However, the problem of the datasets in wide coverage event domains is that their annotations are insufficient and imbalance. One of the methods widely used to deal with this problem is transfer learning. In this work, we aim to extend the transfer learning to utilize multiple source domains. Multiple source domain datasets can be jointly trained to help achieve a higher recognition performance on a target domain with wide coverage events.
RESULTS: Based on the study of previous work, we propose an improved multi-source domain neural network transfer learning architecture and a training approach for biomedical trigger detection task, which can share knowledge between the multi-source and target domains more comprehensively. We extend the ability of traditional adversarial networks to extract common features between source and target domains, when there is more than one dataset in the source domains. Multiple feature extraction channels to simultaneously capture global and local common features are designed. Moreover, under the constraint of an extra classifier, the multiple local common feature sub-channels can extract and transfer more diverse common features from the related multi-source domains effectively. In the experiments, MLEE corpus is used to train and test the proposed model to recognize the wide coverage triggers as a target dataset. Other four corpora with the varying degrees of relevance with MLEE from different domains are used as source datasets, respectively. Our proposed approach achieves recognition improvement compared with traditional adversarial networks. Moreover, its performance is competitive compared with the results of other leading systems on the same MLEE corpus.
CONCLUSIONS: The proposed Multi-Source Transfer Learning-based Trigger Recognizer (MSTLTR) can further improve the performance compared with the traditional method, when the source domains are more than one. The most essential improvement is that our approach represents common features in two aspects: the global common features and the local common features. Hence, these more sharable features improve the performance and generalization of the model on the target domain effectively.

Entities:  

Keywords:  Adversarial networks; Event trigger recognition; Multi-source domains; Transfer learning

Mesh:

Year:  2021        PMID: 33413073      PMCID: PMC7788773          DOI: 10.1186/s12864-020-07315-1

Source DB:  PubMed          Journal:  BMC Genomics        ISSN: 1471-2164            Impact factor:   3.969


  12 in total

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Authors:  Pierre Zweigenbaum; Dina Demner-Fushman; Hong Yu; Kevin B Cohen
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Authors:  Yifan Nie; Wenge Rong; Yiyuan Zhang; Yuanxin Ouyang; Zhang Xiong
Journal:  J Bioinform Comput Biol       Date:  2015-01-11       Impact factor: 1.122

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Authors:  Lishuang Li; Mengzuo Huang; Yang Liu; Shuang Qian; Xinyu He
Journal:  J Biomed Inform       Date:  2019-06-05       Impact factor: 6.317

6.  Event trigger identification for biomedical events extraction using domain knowledge.

Authors:  Deyu Zhou; Dayou Zhong; Yulan He
Journal:  Bioinformatics       Date:  2014-01-30       Impact factor: 6.937

7.  Topic-informed neural approach for biomedical event extraction.

Authors:  Junchi Zhang; Mengchi Liu; Yue Zhang
Journal:  Artif Intell Med       Date:  2019-12-30       Impact factor: 5.326

8.  Event extraction for DNA methylation.

Authors:  Tomoko Ohta; Sampo Pyysalo; Makoto Miwa; Jun'ichi Tsujii
Journal:  J Biomed Semantics       Date:  2011-10-06

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Authors:  Sampo Pyysalo; Tomoko Ohta; Makoto Miwa; Han-Cheol Cho; Jun'ichi Tsujii; Sophia Ananiadou
Journal:  Bioinformatics       Date:  2012-09-15       Impact factor: 6.937

10.  BioBERT: a pre-trained biomedical language representation model for biomedical text mining.

Authors:  Jinhyuk Lee; Wonjin Yoon; Sungdong Kim; Donghyeon Kim; Sunkyu Kim; Chan Ho So; Jaewoo Kang
Journal:  Bioinformatics       Date:  2020-02-15       Impact factor: 6.937

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