Nikolaos Garmpis1, Christos Damaskos2,3, Anna Garmpi4, Vasiliki E Georgakopoulou5,6, Stratigoula Sakellariou7, Aliki Liakea7, Dimitrios Schizas8, Evangelos Diamantis9, Paraskevi Farmaki10, Errika Voutyritsa3, Athanasios Syllaios8, Alexandros Patsouras11, Georgia Sypsa5, Alexandra Agorogianni12, Athanasia Stelianidi10, Efstathios A Antoniou1,3, Konstantinos Kontzoglou1,3, Nikolaos Trakas13, Dimitrios Dimitroulis1. 1. Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 2. Renal Transplantation Unit, Laiko General Hospital, Athens, Greece; x_damaskos@yahoo.gr. 3. N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 4. First Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 5. Department of Pulmonology, Laiko General Hospital, Athens, Greece. 6. First Department of Pulmonology, Sismanogleio Hospital, Athens, Greece. 7. First Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 8. First Department of Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 9. Department of Endocrinology and Diabetes Center, G. Gennimatas General Hospital, Athens, Greece. 10. First Department of Pediatrics, Agia Sofia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 11. Second Department of Internal Medicine, Tzanio General Hospital, Piraeus, Greece. 12. NHS Foundation Trust, Cambridge University Hospital, Cambridge, U.K. 13. Department of Biochemistry, Sismanogleio Hospital, Athens, Greece.
Abstract
BACKGROUND/AIM: Inflammatory fibroid polyp (IFP) is a rare, usually solitary and intraluminal polypoid benign tumor that can affect any part of the gastrointestinal (GI) tract, although in the majority of cases it affects the stomach. This lesion is characterized by proliferation of highly vascular fibrous tissue and infiltration by a variable number of different inflammatory cells. Its etiology is unknown. Our aim was to describe all the reported data concerning IFP. MATERIALS AND METHODS: An extensive search of the PubMed Index was performed for publications with titles or abstracts containing the terms: "inflammatory fibroid polyp" with/without "Vanek". Results were filtered for publications in English and concerning only humans. One hundred and twenty-four publications were finally included in this review. RESULTS: IFP has a female predominance. It affects patients in their 5th decade of life, although there are cases of patients from 4 to 84 years of age. IFP usually affects the stomach and more specifically the gastric antrum but can be detected throughout the GI tract. A significant number of cases remain asymptomatic but the most frequent presentations of IFP are abdominal pain, acute abdomen and GI bleeding. Most cases are treated by endoscopic resection of the lesion. No recurrence nor IFP-specific complications have been reported. Histopathology of IFP varies. CONCLUSION: It is relatively safe to conclude that both the etiology and the timing of diagnosis might change the histopathology, immunohistological staining and tissue structure of IFP. Suggested theories should be taken into consideration with caution as the etiology and pathophysiological mechanisms of IFP are unknown. Copyright
BACKGROUND/AIM: Inflammatory fibroid polyp (IFP) is a rare, usually solitary and intraluminal polypoid benign tumor that can affect any part of the gastrointestinal (GI) tract, although in the majority of cases it affects the stomach. This lesion is characterized by proliferation of highly vascular fibrous tissue and infiltration by a variable number of different inflammatory cells. Its etiology is unknown. Our aim was to describe all the reported data concerning IFP. MATERIALS AND METHODS: An extensive search of the PubMed Index was performed for publications with titles or abstracts containing the terms: "inflammatory fibroid polyp" with/without "Vanek". Results were filtered for publications in English and concerning only humans. One hundred and twenty-four publications were finally included in this review. RESULTS: IFP has a female predominance. It affects patients in their 5th decade of life, although there are cases of patients from 4 to 84 years of age. IFP usually affects the stomach and more specifically the gastric antrum but can be detected throughout the GI tract. A significant number of cases remain asymptomatic but the most frequent presentations of IFP are abdominal pain, acute abdomen and GI bleeding. Most cases are treated by endoscopic resection of the lesion. No recurrence nor IFP-specific complications have been reported. Histopathology of IFP varies. CONCLUSION: It is relatively safe to conclude that both the etiology and the timing of diagnosis might change the histopathology, immunohistological staining and tissue structure of IFP. Suggested theories should be taken into consideration with caution as the etiology and pathophysiological mechanisms of IFP are unknown. Copyright
Authors: D Paikos; J Moschos; D Tzilves; A Koulaouzidis; G Kouklakis; F Patakiouta; K Kontodimou; A Tarpagos; I Katsos Journal: Dig Surg Date: 2007-05-30 Impact factor: 2.588
Authors: D Zissis; A Zizi-Serbetzoglou; X Grammatoglou; C Glava; E Katsamagkou; M E Nikolaidou; T Vasilakaki Journal: J BUON Date: 2009 Jan-Mar Impact factor: 2.533
Authors: F Xavier Moyón; Gabriel A Molina; Katherine Romero; Miguel A Moyón; B Andres Cardenas; Jorge Tufiño; Maria B Almeida; Hernán R González; Paola Moyon Journal: Ann Med Surg (Lond) Date: 2021-05-12