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Literature DB >> 334

Host defense against the pneumococcus in T-lymphocyte-deficient, nude mice.

Abstract

Resistance to pneumococcal infection was tested in T-lymphocyte-deficient, nude (nu/nu) mice. Pneumococcal serum opsonizing activity, in vivo phagocytosis of the pneumococcus, and the mean lethal dose for the pneumococcus were all found to be the same in nude mice as in control (+/+) mice. T-lymphocytes do not appear to play a significant role in the host's defense against the pneumococcus.

Entities: Disease Species

Mesh：

Substances：
Opsonin Proteins

Year: 1975 PMID： 334 PMCID： PMC415421 DOI： 10.1128/iai.12.5.1222-1223.1975

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

8 in total

1. Theta-bearing lymphocytes in nude mice.

Authors: M C Raff
Journal: Nature Date: 1973-12-07 Impact factor: 49.962

2. Evidence for the existence of two functionally distinct types of cells which regulate the antibody response to type 3 pneumococcal polysaccharide.

Authors: P J Baker; P W Stashak; D F Amsbaugh; B Prescott; R F Barth
Journal: J Immunol Date: 1970-12 Impact factor: 5.422

3. Observations on the immunobiology of 'nude' mice.

Authors: E M Pantelouris
Journal: Immunology Date: 1971-02 Impact factor: 7.397

4. Congenital aplasia of the thymus gland (DiGeorge's syndrome).

Authors: R Kretschmer; B Say; D Brown; F S Rosen
Journal: N Engl J Med Date: 1968-12-12 Impact factor: 91.245

5. Absence of thymus in a mouse mutant.

Authors: E M Pantelouris
Journal: Nature Date: 1968-01-27 Impact factor: 49.962

6. Heat labile opsonins to pneumococcus. I. Participation of complement.

Authors: M R Smith; W B Wood
Journal: J Exp Med Date: 1969-12-01 Impact factor: 14.307

7. Heat labile opsonins to pneumococcus. II. Involvement of C3 and C5.

Authors: H S Shin; M R Smith; W B Wood
Journal: J Exp Med Date: 1969-12-01 Impact factor: 14.307

8. Effects on C-reactive protein on the lymphoid system. I. Binding to thymus-dependent lymphocytes and alteration of their functions.

Authors: R F Mortensen; A P Osmand; H Gewurz
Journal: J Exp Med Date: 1975-04-01 Impact factor: 14.307

8 in total

9 in total

Review 1. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research.

Authors: D G Baker
Journal: Clin Microbiol Rev Date: 1998-04 Impact factor: 26.132

2. Trypanosoma rhodesiense infection in congenitally athymic (nude) mice.

Authors: G H Campbell; K M Esser; S M Phillips
Journal: Infect Immun Date: 1978-06 Impact factor: 3.441

3. Histoplasma capsulatum infection in nude mice.

Authors: D M Williams; J R Graybill; D J Drutz
Journal: Infect Immun Date: 1978-09 Impact factor: 3.441

4. Transfer of immunity against lethal murine Francisella infection by specific antibody depends on host gamma interferon and T cells.

Authors: T R Rhinehart-Jones; A H Fortier; K L Elkins
Journal: Infect Immun Date: 1994-08 Impact factor: 3.441