Literature DB >> 307540

Trypanosoma rhodesiense infection in congenitally athymic (nude) mice.

G H Campbell, K M Esser, S M Phillips.   

Abstract

Athymic nude mice (nu/nu), heterozygous litter mates (nu/+), and thymic reconstituted homozygous animals (nu/nu TxR) were infected with Trypanosoma rhodesiense. A reduced parasitemia and prolonged survival were observed in the nu/nu animals after infection and cure or after immunization with irradiated organisms. These studies indicate that resistance of mice to T. rhodesiense infection is relatively independent of thymic lymphocyte function.

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Year:  1978        PMID： 307540      PMCID： PMC421917          DOI： 10.1128/iai.20.3.714-720.1978

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  34 in total

1.  Fluorescent antibody reactions in Trypanosoma rhodesiense and T. gambiense in experimental animals.

Authors:  J S WILLIAMS; R E DUXBURY; R I ANDERSON; E H SADUN
Journal:  J Parasitol       Date:  1963-06       Impact factor: 1.276

2.  Suppressor cells in mice infected with Trypanosoma brucei.

Authors:  D D Eardley; A N Jayawardena
Journal:  J Immunol       Date:  1977-09       Impact factor: 5.422

3.  T lymphocytes and the transfer of immunity to Trypanosoma musculi in mice.

Authors:  P Pouliot; P Viens; G A Targett
Journal:  Clin Exp Immunol       Date:  1977-03       Impact factor: 4.330

4.  Suppressor cells in experimentally trypanosomiasis.

Authors:  A N Jayawardena; B H Waksman
Journal:  Nature       Date:  1977-02-10       Impact factor: 49.962

5.  Experimental infections with African trypanosomes. V. Preliminary parasitological, clinical, hematological, serological, and pathological observations in rhesus monkeys infected with Trypanosoma rhodesiense.

Authors:  E H Sadun; A J Johnson; R B Nagle; R E Duxbury
Journal:  Am J Trop Med Hyg       Date:  1973-05       Impact factor: 2.345

6.  Absence of thymus in a mouse mutant.

Authors:  E M Pantelouris
Journal:  Nature       Date:  1968-01-27       Impact factor: 49.962

7.  Trypanosoma rhodesiense infection in B-cell-deficient mice.

Authors:  G H Campbell; K M Esser; F I Weinbaum
Journal:  Infect Immun       Date:  1977-11       Impact factor: 3.441

8.  Adoptive transfer of variant-specific resistance to Trypanosoma rhodesiense with B lymphocytes and serum.

Authors:  G H Campbell; S M Phillips
Journal:  Infect Immun       Date:  1976-11       Impact factor: 3.441

9.  Chronic infection with Trypanosoma musculi in congenitally athymic nude mice.

Authors:  R G Rank; D W Roberts; W P Weidanz
Journal:  Infect Immun       Date:  1977-05       Impact factor: 3.441

10.  Schistosomiasis in the congenitally athymic (nude) mouse. I. Thymic dependency of eosinophilia, granuloma formation, and host morbidity.

Authors:  S M Phillips; J J DiConza; J A Gold; W A Reid
Journal:  J Immunol       Date:  1977-02       Impact factor: 5.422
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  10 in total

1.  In vitro and in vivo neutralization of the relapsing fever agent Borrelia hermsii with serotype-specific immunoglobulin M antibodies.

Authors:  A G Barbour; V Bundoc
Journal:  Infect Immun       Date:  2001-02       Impact factor: 3.441

2.  Parasite-specific T-cell responses of trypanotolerant and trypanosusceptible cattle during infection with Trypanosoma congolense.

Authors:  J N Flynn; M Sileghem; D J Williams
Journal:  Immunology       Date:  1992-04       Impact factor: 7.397

3.  Effect of visceral leishmaniasis on congenitally athymic mice.

Authors:  L L Smrkovski; C L Larson; S G Reed
Journal:  Infect Immun       Date:  1979-09       Impact factor: 3.441

4.  Trypanosome variant surface glycoproteins are recognized by self-reactive antibodies in uninfected hosts.

Authors:  N Müller; J M Mansfield; T Seebeck
Journal:  Infect Immun       Date:  1996-11       Impact factor: 3.441

5.  T-cell-independent and T-cell-dependent B-cell responses to exposed variant surface glycoprotein epitopes in trypanosome-infected mice.

Authors:  D M Reinitz; J M Mansfield
Journal:  Infect Immun       Date:  1990-07       Impact factor: 3.441

6.  Thymus-dependent control of host defense mechanisms against Trypanosoma cruzi infection.

Authors:  F Kierszenbaum; M M Pienkowski
Journal:  Infect Immun       Date:  1979-04       Impact factor: 3.441

7.  Antibody responses induced by immunization of inbred mice susceptible and resistant to African trypanosomes.

Authors:  L A Mitchell; T W Pearson
Journal:  Infect Immun       Date:  1983-06       Impact factor: 3.441

8.  Trypanosomiasis in mice with naturally occurring immunodeficiencies.

Authors:  J F Jones; G E Hancock
Journal:  Infect Immun       Date:  1983-11       Impact factor: 3.441

9.  Influence of source and quantity of protein on the development of immunity and resistance to African trypanosomiasis.

Authors:  J D Norton; S P Yang; P Diffley
Journal:  Infect Immun       Date:  1986-02       Impact factor: 3.441

10.  Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. II. Immunobiological dysfunctions.

Authors:  Marie Christine Blom-Potar; Nathalie Chamond; Alain Cosson; Grégory Jouvion; Sabrina Droin-Bergère; Michel Huerre; Paola Minoprio
Journal:  PLoS Negl Trop Dis       Date:  2010-08-10
  10 in total

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