Literature DB >> 33393789

Epimerization-Free C-Term Activation of Peptide Fragments by Ball Milling.

Yves Yeboue1, Marion Jean2, Gilles Subra1, Jean Martinez1, Frédéric Lamaty1, Thomas-Xavier Métro1.   

Abstract

Peptides were produced in high yields and, if any, very low epimerization, by mechanochemical coupling of peptide fragments containing highly epimerization-prone and/or highly hindered amino acids at C-term. Ball milling was clearly identified as the key element enabling one to obtain such results.

Year:  2021        PMID： 33393789     DOI： 10.1021/acs.orglett.0c03209

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

Review 1.  Mechanochemistry: New Tools to Navigate the Uncharted Territory of "Impossible" Reactions.

Authors:  Federico Cuccu; Lidia De Luca; Francesco Delogu; Evelina Colacino; Niclas Solin; Rita Mocci; Andrea Porcheddu
Journal:  ChemSusChem       Date:  2022-07-21       Impact factor: 9.140

2.  Glycerol Valorization towards a Benzoxazine Derivative through a Milling and Microwave Sequential Strategy.

Authors:  Miguel Ángel Torres-Pastor; Claudia Espro; Maurizio Selva; Alvise Perosa; Antonio A Romero Reyes; Sameh M Osman; Rafael Luque; Daily Rodríguez-Padrón
Journal:  Molecules       Date:  2022-01-19       Impact factor: 4.411

3.  Cost-efficient and user-friendly 17O/18O labeling procedures of fatty acids using mechanochemistry.

Authors:  Jessica Špačková; Charlyn Fabra; Guillaume Cazals; Marie Hubert-Roux; Isabelle Schmitz-Afonso; Ieva Goldberga; Dorothée Berthomieu; Aurélien Lebrun; Thomas-Xavier Métro; Danielle Laurencin
Journal:  Chem Commun (Camb)       Date:  2021-07-08       Impact factor: 6.222
  3 in total

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