| Literature DB >> 33390521 |
Unwoo Kang1, Dongdong Wang1, Heidi R Bokesch1,2, Kirk R Gustafson1.
Abstract
Four new pregnane steroids, 3β,4β,16β-trihydroxypregna-5,17-diene-10,2-carbolactone (1), 16β-acetoxy-3β,4β-dihydroxypregna-5,17-diene-10,2-carbolactone (2), 12β-acetoxy-3β,4β,16β-trihydroxypregna-5,17-diene-10,2-carbolactone (3), and 12β,16β-diacetoxy-3β,4β-dihydroxypregna-5,17-diene-10,2-carbolactone (4) were isolated from an extract of an Epipolasis sp. marine sponge. The structures of the new compounds were determined by extensive NMR spectroscopic analysis and comparison with data from previously reported compounds.Entities:
Keywords: Epipolasis; carbolactone; marine sponge; pregnane steroid; structure elucidation
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Year: 2021 PMID： 33390521 PMCID： PMC9341129 DOI： 10.1248/cpb.c20-00128
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.903