Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A two-dimensional NMR study of the antimicrobial peptide magainin 2.

Literature DB >> 3338566

A two-dimensional NMR study of the antimicrobial peptide magainin 2.

Abstract

Using two-dimensional NMR spectroscopy, a complete 1H resonance assignment has been obtained for the peptide magainin 2 recently isolated from Xenopus laevis. It is demonstrated that this peptide adopts an alpha-helical structure with amphiphilic character when dissolved in a mixture of trifluoroethanol (TFE) and H2O. The transition to the alpha-helical conformation occurs at very low concentrations of TFE.

Entities: Chemical Species

Mesh：

Substances：

Year: 1988 PMID： 3338566 DOI： 10.1016/0014-5793(88)81405-4

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

Keyword Cloud
Cited

34 in total

1. Structure-function relationships in novel peptide dodecamerswith broad-spectrum bactericidal and endotoxin-neutralizing activities.

Authors: K H Mayo; J Haseman; H C Young; J W Mayo
Journal: Biochem J Date: 2000-08-01 Impact factor: 3.857

2. Barrel-stave model or toroidal model? A case study on melittin pores.

Authors: L Yang; T A Harroun; T M Weiss; L Ding; H W Huang
Journal: Biophys J Date: 2001-09 Impact factor: 4.033

3. Interleukin 2 promoter/enhancer controlled expression of a synthetic cecropin-class lytic peptide in transgenic mice and subsequent resistance to Brucella abortus.

Authors: W A Reed; P H Elzer; F M Enright; J M Jaynes; J D Morrey; K L White
Journal: Transgenic Res Date: 1997-09 Impact factor: 2.788

4. Structure and interactions of magainin antibiotic peptides in lipid bilayers: a solid-state nuclear magnetic resonance investigation.

Authors: B Bechinger; M Zasloff; S J Opella
Journal: Biophys J Date: 1992-04 Impact factor: 4.033

9. Analysis of the flexibility and stability of the structure of magainin in a bilayer, and in aqueous and nonaqueous solutions using molecular dynamics simulations.

Authors: Elham Esmaili; Mohsen Shahlaei
Journal: J Mol Model Date: 2015-03-08 Impact factor: 1.810

10. Novel synthetic antimicrobial peptides effective against methicillin-resistant Staphylococcus aureus.

Authors: J Alvarez-Bravo; S Kurata; S Natori
Journal: Biochem J Date: 1994-09-01 Impact factor: 3.857

A two-dimensional NMR study of the antimicrobial peptide magainin 2.

1. Structure-function relationships in novel peptide dodecamerswith broad-spectrum bactericidal and endotoxin-neutralizing activities.

2. Barrel-stave model or toroidal model? A case study on melittin pores.

3. Interleukin 2 promoter/enhancer controlled expression of a synthetic cecropin-class lytic peptide in transgenic mice and subsequent resistance to Brucella abortus.

4. Structure and interactions of magainin antibiotic peptides in lipid bilayers: a solid-state nuclear magnetic resonance investigation.

5. Orientations of amphipathic helical peptides in membrane bilayers determined by solid-state NMR spectroscopy.

6. Common mechanism unites membrane poration by amyloid and antimicrobial peptides.

Review 7. A common landscape for membrane-active peptides.

8. Magainins and the disruption of membrane-linked free-energy transduction.

9. Analysis of the flexibility and stability of the structure of magainin in a bilayer, and in aqueous and nonaqueous solutions using molecular dynamics simulations.

10. Novel synthetic antimicrobial peptides effective against methicillin-resistant Staphylococcus aureus.